| Protein name |
Lariatin (Class II lasso peptide) (Lariat peptide) (Ribosomally synthesized and post-translationally modified peptide) (RiPP) [Cleaved into: Lariatin-A; Lariatin-B] |
| NCBI Accession ID |
AB593691.1 |
| Organism |
Rhodococcus jostii |
| Left |
461 |
| Right |
601 |
| Strand |
+ |
| Nucleotide Sequence |
ATGACCTCTCAGCCGAGCAAGAAGACGTACAATGCACCGAGCCTGGTGCAGCGGGGGAAGTTCGCACGAACCACAGCAGGTTCTCAGCTGGTCTATCGCGAGTGGGTCGGGCATTCAAACGTCATTAAGCCCGGCCCCTAA |
| Sequence |
MTSQPSKKTYNAPSLVQRGKFARTTAGSQLVYREWVGHSNVIKPGP |
| Source of smORF |
Swiss-Prot |
| Function |
[Lariatin-A]: Peptide antibiotic with selective activity against Mycobacterium species (M.smegmatis, MIC=3.13 ug/ml and M.tuberculosis, MIC=0.39 ug/ml). it is plausible that the target of lariatins lies within the cell wall in mycobacteria. {ECO:0000269|Pubmed:17617692}.; [Lariatin-B]: Peptide antibiotic with selective activity against Mycobacterium species (M.smegmatis, MIC=6.25 ug/ml). {ECO:0000269|Pubmed:17617692}. |
| Pubmed ID |
22388571
17617692
19362475
16756302
|
| Domain |
|
| Functional Category |
Antimicrobial |
| Uniprot ID |
H7C8I3
|
| ORF Length (Amino Acid) |
46 |