Result : A1KT54
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Protein RnfH |
| NCBI Accession ID | AM421808.1 |
| Organism | Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18) |
| Left | 765818 |
| Right | 766096 |
| Strand | - |
| Nucleotide Sequence | ATGCTTGAAATTGAGATTGTGTACGGGCTGCCCGACCGACAGGTTTTGAAAACCATGCAGCTTGCCGAAGGAACAACCGTCCGCGCCGCCGCACTGCAAAGCGGTTTGGACGGCATATTTGAAGATTTAAACCTGCATTCCGCGCCTTTGGGCATTTTCGGCAAAGCCGTCAAAGACGACACGCCGCTGCGCGACGGCGACCGCATCGAAGTGTACCGCCCGCTGTTGATCGACCCCAAAGAAGCGCGCCGCAAACGCGTTCAAAATCAAGAAGAATAA |
| Sequence | MLEIEIVYGLPDRQVLKTMQLAEGTTVRAAALQSGLDGIFEDLNLHSAPLGIFGKAVKDDTPLRDGDRIEVYRPLLIDPKEARRKRVQNQEE |
| Source of smORF | Swiss-Prot |
| Function | The ORF matches to the profile of cl28922. Profile Description: Beta-grasp ubiquitin-like fold. This domain is the binding/interacting region of several protein kinases, such as the Schizosaccharomyces pombe Byr2. Byr2 is a Ser/Thr-specific protein kinase acting as mediator of signals for sexual differentiation in S. pombe by initiating a MAPK module, which is a highly conserved element in eukaryotes. Byr2 is activated by interacting with Ras, which then translocates the molecule to the plasma membrane. Ras proteins are key elements in intracellular signaling and are involved in a variety of vital processes such as DNA transcription, growth control, and differentiation. They function like molecular switches cycling between GTP-bound 'on' and GDP-bound 'off' states. |
| Pubmed ID | 17305430 |
| Domain | CDD:421700 |
| Functional Category | Others |
| Uniprot ID | A1KT54 |
| ORF Length (Amino Acid) | 92 |
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| Conservation Analysis |
No. of Species: 67
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 444252 | 444530 | - | NZ_CP021520.1 | Neisseria meningitidis |
| 2 | 1694673 | 1694951 | - | NZ_CP012028.1 | Neisseria gonorrhoeae |
| 3 | 504256 | 504534 | - | NZ_CP031253.1 | Neisseria lactamica |
| 4 | 421324 | 421602 | - | NZ_LS483369.1 | Neisseria cinerea |
| 5 | 1754505 | 1754783 | - | NZ_CP031325.1 | Neisseria polysaccharea |
| 6 | 2085943 | 2086221 | + | NZ_CP046027.1 | Neisseria brasiliensis |
| 7 | 922421 | 922693 | - | NZ_CP039886.1 | Neisseria flavescens |
| 8 | 995132 | 995404 | - | NZ_CP039887.1 | Neisseria subflava |
| 9 | 1839051 | 1839323 | + | NZ_CP031699.1 | Neisseria animalis |
| 10 | 1015966 | 1016241 | + | NZ_CP072524.1 | Neisseria sicca |
| 11 | 1998082 | 1998366 | - | NZ_LT906434.1 | Neisseria zoodegmatis |
| 12 | 1220481 | 1220765 | - | NZ_LR134516.1 | Neisseria animaloris |
| 13 | 5592 | 5864 | - | NZ_CP022278.1 | Neisseria chenwenguii |
| 14 | 1506379 | 1506672 | + | NZ_CP031700.1 | Neisseria zalophi |
| 15 | 2161156 | 2161431 | + | NZ_LR134533.1 | Neisseria weaveri |
| 16 | 2334977 | 2335219 | + | NZ_LR134313.1 | Neisseria canis |
| 17 | 1613672 | 1613956 | + | NZ_CP059567.1 | Neisseria shayeganii |
| 18 | 686991 | 687281 | - | NZ_CP031252.1 | Neisseria elongata |
| 19 | 165582 | 165863 | + | NZ_CP060414.1 | Neisseria musculi |
| 20 | 1119533 | 1119829 | - | NZ_CP059571.1 | Neisseria bacilliformis |
| 21 | 2264417 | 2264659 | + | NZ_CP059565.1 | Neisseria wadsworthii |
| 22 | 1618067 | 1618342 | - | NZ_CP059564.1 | Alysiella filiformis |
| 23 | 1458103 | 1458375 | - | NZ_CP019448.1 | Simonsiella muelleri ATCC 29453 |
| 24 | 909664 | 909966 | + | NZ_CP062252.1 | Pseudomonas allokribbensis |
| 25 | 455330 | 455569 | - | NZ_CP029495.1 | Chromobacterium phragmitis |
| 26 | 766514 | 766765 | + | NZ_CP014544.1 | Zhongshania aliphaticivorans |
| 27 | 4259137 | 4259439 | - | NZ_CP014205.2 | Pseudomonas glycinae |
| 28 | 817716 | 817991 | + | NZ_LT906482.1 | Eikenella corrodens |
| 29 | 920686 | 920988 | + | NZ_CP029608.1 | Pseudomonas kribbensis |
| 30 | 918710 | 919012 | + | NZ_CP051487.1 | Pseudomonas umsongensis |
| 31 | 5197167 | 5197469 | - | NZ_CP070503.1 | Pseudomonas atacamensis |
| 32 | 1190143 | 1190466 | + | NZ_CP009795.1 | Burkholderia dolosa AU0158 |
| 33 | 2236021 | 2236314 | - | NZ_LR134327.1 | Aggregatibacter aphrophilus ATCC 33389 |
| 34 | 125417 | 125749 | + | NZ_CP015031.1 | Basfia succiniciproducens |
| 35 | 520183 | 520515 | + | NC_006300.1 | [Mannheimia] succiniciproducens MBEL55E |
| 36 | 5771631 | 5771933 | - | NZ_CP014870.1 | Pseudomonas silesiensis |
| 37 | 1872089 | 1872364 | + | NZ_CP038018.1 | Eikenella exigua |
| 38 | 768184 | 768447 | - | NZ_CP040863.1 | Rodentibacter heylii |
| 39 | 942906 | 943208 | + | NZ_CP062253.1 | Pseudomonas gozinkensis |
| 40 | 1503864 | 1504136 | - | NZ_CP041335.1 | Chitinolyticbacter meiyuanensis |
| 41 | 1098314 | 1098607 | + | NZ_CP013124.1 | Pseudomonas mendocina S5.2 |
| 42 | 5540722 | 5541024 | - | NZ_CP027756.1 | Pseudomonas synxantha |
| 43 | 731520 | 731825 | + | NZ_CP059569.1 | Kingella oralis |
| 44 | 4118909 | 4119211 | - | NZ_CP062158.2 | Pseudomonas lundensis |
| 45 | 1142621 | 1142914 | - | NZ_CP070505.1 | Pseudomonas toyotomiensis |
| 46 | 4272742 | 4273035 | - | NZ_CP068551.1 | Pseudomonas khazarica |
| 47 | 1368682 | 1368936 | + | NZ_CP060009.1 | Pseudomonas sediminis |
| 48 | 1047867 | 1048187 | - | NZ_CP012362.1 | Oblitimonas alkaliphila |
| 49 | 834637 | 834945 | - | NZ_CP019343.1 | Oceanicoccus sagamiensis |
| 50 | 1826787 | 1827083 | - | NZ_CP045302.1 | Azotobacter salinestris |
| 51 | 3224436 | 3224738 | - | NZ_CP048810.1 | Pseudomonas bijieensis |
| 52 | 4343064 | 4343357 | - | NC_012560.1 | Azotobacter vinelandii DJ |
| 53 | 3755636 | 3755941 | - | NZ_CP012676.1 | Pseudomonas versuta |
| 54 | 916768 | 917070 | + | NZ_CP035088.1 | Pseudomonas viciae |
| 55 | 5698096 | 5698398 | - | NZ_CP012400.2 | Pseudomonas yamanorum |
| 56 | 942522 | 942851 | + | NZ_CP010554.1 | Rugosibacter aromaticivorans |
| 57 | 849104 | 849361 | + | NZ_CP007039.1 | Pseudomonas cichorii JBC1 |
| 58 | 5202002 | 5202304 | - | NZ_CP023272.1 | Pseudomonas lurida |
| 59 | 5892579 | 5892881 | - | NZ_CP018420.1 | Pseudomonas veronii |
| 60 | 1521018 | 1521251 | + | NZ_CP059563.1 | Conchiformibius steedae |
| 61 | 5246620 | 5246922 | - | NZ_CP010896.1 | Pseudomonas simiae |
| 62 | 5193751 | 5194056 | - | NZ_CP049044.1 | Pseudomonas psychrophila |
| 63 | 2968022 | 2968270 | - | NZ_CP005960.1 | Pseudomonas mandelii JR-1 |
| 64 | 1740240 | 1740524 | - | NC_014394.1 | Gallionella capsiferriformans ES-2 |
| 65 | 1778175 | 1778459 | - | NZ_AP021889.1 | Thiosulfatimonas sediminis |
| 66 | 5002200 | 5002499 | - | NZ_CP027723.1 | Pseudomonas orientalis |
| 67 | 1388585 | 1388830 | - | NC_007614.1 | Nitrosospira multiformis ATCC 25196 |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NZ_CP021520.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF03364.22 | 0.94 | 63 | 5 | same-strand | Polyketide cyclase / dehydrase and lipid transport |
| 2 | PF10604.11 | 0.88 | 59 | 5 | same-strand | Polyketide cyclase / dehydrase and lipid transport |
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