Result : A1JT31
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Negative regulator of flagellin synthesis (Anti-sigma-28 factor) |
| NCBI Accession ID | U16136.1 |
| Organism | Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) |
| Left | 90 |
| Right | 389 |
| Strand | + |
| Nucleotide Sequence | ATGAGTATTGATCGCACTCAGCCGCTATTACCGGTAACACCAGTGCAGCCACGGGAAACCAGTGATATTGCGCAACAAACGCGTAAACCTTCTGCTCAATCAAAAACACCGGTAAGTGGTACTGAGGTTAAATTGAGCGACGCGCAGGCAAAATTGATGCAACCGGGCAGCCAGGACATCAATGTAGAACGTGTCGAAACCTTAAAACAGGCGATCCGTTCAGGCCAACTGACCATGGACACCGGTAAAATTGCCGATGCCTTGCTCAAAAATGTTGCCGATGACCTGAAGAATAGCTAA |
| Sequence | MSIDRTQPLLPVTPVQPRETSDIAQQTRKPSAQSKTPVSGTEVKLSDAQAKLMQPGSQDINVERVETLKQAIRSGQLTMDTGKIADALLKNVADDLKNS |
| Source of smORF | Swiss-Prot |
| Function | Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA (By similarity). {ECO:0000250}. |
| Pubmed ID | 8830263 17173484 |
| Domain | CDD:412716 |
| Functional Category | Others |
| Uniprot ID | A1JT31 |
| ORF Length (Amino Acid) | 99 |
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| Conservation Analysis |
No. of Species: 119
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 2829937 | 2830236 | + | NZ_CP011118.1 | Yersinia enterocolitica |
| 2 | 96204 | 96503 | - | NZ_CP009781.1 | Yersinia aldovae 670-83 |
| 3 | 2278464 | 2278763 | + | NZ_CP032487.1 | Yersinia hibernica |
| 4 | 2797298 | 2797597 | + | NZ_CP043727.1 | Yersinia canariae |
| 5 | 1852028 | 1852327 | - | NZ_CP046293.1 | Yersinia intermedia |
| 6 | 244064 | 244363 | - | NZ_CP009787.1 | Yersinia rohdei |
| 7 | 3091313 | 3091612 | - | NZ_CP054043.1 | Yersinia mollaretii ATCC 43969 |
| 8 | 3689195 | 3689497 | - | NZ_CP007230.1 | Yersinia similis |
| 9 | 2552942 | 2553244 | + | NZ_LR134373.1 | Yersinia pseudotuberculosis |
| 10 | 811236 | 811532 | + | NZ_CP011078.1 | Yersinia ruckeri |
| 11 | 2889003 | 2889299 | + | NZ_CP034036.1 | Brenneria nigrifluens DSM 30175 = ATCC 13028 |
| 12 | 2754155 | 2754454 | + | NZ_CP050150.1 | Hafnia alvei |
| 13 | 5397662 | 5397973 | + | NZ_CP011254.1 | Serratia fonticola |
| 14 | 2981270 | 2981569 | + | NZ_CP025799.1 | Dickeya zeae |
| 15 | 1770425 | 1770724 | - | NC_012912.1 | Dickeya chrysanthemi Ech1591 |
| 16 | 3081739 | 3082035 | + | NZ_CP065044.1 | Pectobacterium aroidearum |
| 17 | 3159068 | 3159364 | + | NZ_CP009125.1 | Pectobacterium atrosepticum |
| 18 | 1925642 | 1925938 | - | NZ_CP034938.1 | Pectobacterium odoriferum |
| 19 | 1905629 | 1905925 | + | NZ_CP017482.1 | Pectobacterium polaris |
| 20 | 4878506 | 4878802 | + | NZ_CP015750.1 | Pectobacterium wasabiae CFBP 3304 |
| 21 | 319136 | 319435 | + | NZ_CP015137.1 | Dickeya solani IPO 2222 |
| 22 | 2128079 | 2128375 | + | NZ_CP015749.1 | Pectobacterium parmentieri |
| 23 | 4575682 | 4575978 | + | NZ_CP047495.1 | Pectobacterium brasiliense |
| 24 | 1802883 | 1803179 | - | NZ_CP051652.1 | Pectobacterium carotovorum |
| 25 | 2956234 | 2956530 | + | NZ_CP038498.1 | Pectobacterium punjabense |
| 26 | 1453183 | 1453482 | - | NZ_LT615367.1 | Dickeya aquatica |
| 27 | 3074285 | 3074584 | + | NC_014500.1 | Dickeya dadantii 3937 |
| 28 | 4643422 | 4643721 | - | NZ_CP009460.1 | Dickeya fangzhongdai |
| 29 | 3200434 | 3200730 | - | NZ_CP006664.1 | Edwardsiella anguillarum ET080813 |
| 30 | 2391852 | 2392148 | + | NZ_CP016043.1 | Edwardsiella hoshinae |
| 31 | 447428 | 447724 | + | NZ_CP023706.1 | Edwardsiella tarda |
| 32 | 3007731 | 3008030 | + | NZ_CP031560.1 | Dickeya dianthicola |
| 33 | 1580294 | 1580593 | - | NZ_CP042220.2 | Dickeya poaceiphila |
| 34 | 1331863 | 1332159 | - | NC_012779.2 | Edwardsiella ictaluri 93-146 |
| 35 | 2875168 | 2875461 | + | NZ_LR134201.1 | Cedecea lapagei |
| 36 | 3155053 | 3155364 | + | NZ_LT906479.1 | Serratia ficaria |
| 37 | 3252956 | 3253282 | + | NC_015567.1 | Serratia plymuthica AS9 |
| 38 | 3239587 | 3239913 | + | NZ_CP048784.1 | Serratia liquefaciens |
| 39 | 2424383 | 2424694 | + | NZ_CP016948.1 | Serratia surfactantfaciens |
| 40 | 1973301 | 1973612 | - | NZ_CP071320.1 | Serratia ureilytica |
| 41 | 3125734 | 3126045 | + | NZ_CP038662.1 | Serratia nematodiphila |
| 42 | 510136 | 510429 | + | NZ_CP044098.1 | Citrobacter portucalensis |
| 43 | 1856141 | 1856434 | + | NC_009792.1 | Citrobacter koseri ATCC BAA-895 |
| 44 | 2519802 | 2520092 | - | NZ_CP051548.1 | Phytobacter diazotrophicus |
| 45 | 3094787 | 3095080 | + | NZ_CP023525.1 | Cedecea neteri |
| 46 | 3270532 | 3270858 | + | NZ_LR134494.1 | Serratia quinivorans |
| 47 | 4170793 | 4171098 | + | NZ_CP007044.2 | Chania multitudinisentens RB-25 |
| 48 | 4607693 | 4607986 | - | NZ_CP033744.1 | Citrobacter freundii |
| 49 | 2240167 | 2240463 | + | NZ_CP014137.1 | Brenneria goodwinii |
| 50 | 1772785 | 1773078 | - | NZ_LR134340.1 | Escherichia marmotae |
| 51 | 1723516 | 1723809 | - | NZ_CP017184.1 | Enterobacter roggenkampii |
| 52 | 783224 | 783517 | + | NZ_CP025034.2 | Enterobacter sp. SGAir0187 |
| 53 | 3646277 | 3646570 | - | NZ_CP053416.1 | Salmonella bongori |
| 54 | 1568523 | 1568816 | + | NZ_CP038469.1 | Citrobacter tructae |
| 55 | 4490045 | 4490356 | + | NZ_CP065640.1 | Serratia rubidaea |
| 56 | 1840227 | 1840526 | - | NC_014306.1 | Erwinia billingiae Eb661 |
| 57 | 3019574 | 3019861 | + | NZ_CP013990.1 | Leclercia adecarboxylata |
| 58 | 1993337 | 1993630 | - | NZ_CP043318.1 | Enterobacter chengduensis |
| 59 | 1789525 | 1789818 | - | NZ_CP027986.1 | Enterobacter sichuanensis |
| 60 | 1257036 | 1257329 | - | NC_003197.2 | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |
| 61 | 1230047 | 1230340 | - | NC_013716.1 | Citrobacter rodentium ICC168 |
| 62 | 1442822 | 1443118 | - | NZ_CP034035.1 | Brenneria rubrifaciens |
| 63 | 1757947 | 1758240 | - | NZ_AP022508.1 | Enterobacter bugandensis |
| 64 | 2777713 | 2778006 | + | NZ_AP023184.1 | Buttiauxella agrestis |
| 65 | 1770310 | 1770603 | - | NZ_CP009756.1 | Enterobacter cloacae |
| 66 | 3332936 | 3333259 | + | NZ_LR134475.1 | Klebsiella aerogenes |
| 67 | 1253104 | 1253394 | - | NZ_CP011602.1 | Phytobacter ursingii |
| 68 | 4248655 | 4248948 | - | NZ_AP019007.1 | Enterobacter oligotrophicus |
| 69 | 1742936 | 1743229 | - | NC_015968.1 | Enterobacter soli |
| 70 | 1736637 | 1736930 | + | NZ_CP045769.1 | Enterobacter cancerogenus |
| 71 | 938927 | 939220 | - | NZ_CP017279.1 | Enterobacter ludwigii |
| 72 | 1895574 | 1895867 | - | NZ_CP015113.1 | Kosakonia radicincitans |
| 73 | 3902155 | 3902454 | + | NZ_CP026364.1 | Proteus hauseri |
| 74 | 897103 | 897396 | + | NZ_CP057657.1 | Escherichia fergusonii |
| 75 | 953595 | 953894 | - | NZ_CP028271.1 | Mixta intestinalis |
| 76 | 2766822 | 2767115 | + | NZ_CP072455.1 | Xenorhabdus budapestensis |
| 77 | 1708603 | 1708896 | - | NZ_CP061527.1 | Shigella dysenteriae |
| 78 | 1489120 | 1489413 | - | NC_002695.2 | Escherichia coli O157:H7 str. Sakai |
| 79 | 1117596 | 1117889 | - | NC_004337.2 | Shigella flexneri 2a str. 301 |
| 80 | 1129835 | 1130128 | - | NC_000913.3 | Escherichia coli str. K-12 substr. MG1655 |
| 81 | 3302075 | 3302368 | + | NZ_CP014007.2 | Kosakonia oryzae |
| 82 | 1713598 | 1713897 | - | NZ_CP061511.1 | Mixta calida |
| 83 | 2364367 | 2364660 | + | NZ_CP012268.1 | Cronobacter muytjensii ATCC 51329 |
| 84 | 1717850 | 1718143 | - | NZ_CP012266.1 | Cronobacter dublinensis subsp. dublinensis LMG 23823 |
| 85 | 1137967 | 1138260 | - | NZ_AP014857.1 | Escherichia albertii |
| 86 | 3033277 | 3033579 | + | NC_012962.1 | Photorhabdus asymbiotica |
| 87 | 1540839 | 1541147 | - | NZ_LN907827.1 | Erwinia gerundensis |
| 88 | 1730048 | 1730341 | + | NZ_CP027107.1 | Cronobacter sakazakii |
| 89 | 2475012 | 2475305 | + | NZ_CP013940.1 | Cronobacter malonaticus LMG 23826 |
| 90 | 470076 | 470375 | - | NZ_CP016176.1 | Xenorhabdus hominickii |
| 91 | 1144944 | 1145237 | + | NZ_CP045300.1 | Kosakonia arachidis |
| 92 | 1174964 | 1175257 | + | NZ_CP016337.1 | Kosakonia sacchari |
| 93 | 1893654 | 1893947 | - | NZ_CP063425.1 | Kosakonia pseudosacchari |
| 94 | 2305411 | 2305710 | + | NC_010694.1 | Erwinia tasmaniensis Et1/99 |
| 95 | 2280636 | 2280938 | - | NC_005126.1 | Photorhabdus laumondii subsp. laumondii TTO1 |
| 96 | 2904000 | 2904302 | + | NC_017554.1 | Pantoea ananatis PA13 |
| 97 | 4912882 | 4913184 | + | NZ_CP011104.1 | Photorhabdus thracensis |
| 98 | 1505254 | 1505562 | - | NZ_CP034148.1 | Pantoea agglomerans |
| 99 | 638568 | 638867 | - | NZ_CP023529.1 | Lelliottia amnigena |
| 100 | 2862690 | 2862983 | + | NZ_CP035129.1 | Kosakonia cowanii |
| 101 | 1680972 | 1681265 | - | NZ_CP012264.1 | Cronobacter condimenti 1330 |
| 102 | 1884689 | 1884988 | - | NC_013892.1 | Xenorhabdus bovienii SS-2004 |
| 103 | 1572200 | 1572499 | - | NZ_CP023567.1 | Erwinia pyrifoliae |
| 104 | 1668276 | 1668569 | - | NZ_CP012257.1 | Cronobacter universalis NCTC 9529 |
| 105 | 2797066 | 2797362 | + | NZ_CP054058.1 | Scandinavium goeteborgense |
| 106 | 2615089 | 2615397 | + | NZ_CP045720.1 | Pantoea eucalypti |
| 107 | 774203 | 774505 | - | NZ_CP067057.1 | Rahnella aceris |
| 108 | 1877030 | 1877323 | - | NZ_CP012871.1 | [Enterobacter] lignolyticus |
| 109 | 1766296 | 1766595 | + | NC_010554.1 | Proteus mirabilis HI4320 |
| 110 | 48132 | 48428 | + | NZ_CP042941.1 | Atlantibacter hermannii |
| 111 | 4409401 | 4409703 | - | NZ_CP049115.1 | Pantoea stewartii |
| 112 | 1523188 | 1523487 | - | NC_013961.1 | Erwinia amylovora CFBP1430 |
| 113 | 1770871 | 1771170 | - | NZ_CP026377.1 | Mixta gaviniae |
| 114 | 2182840 | 2183139 | + | NZ_CP060401.1 | Xenorhabdus nematophila |
| 115 | 3649000 | 3649293 | + | NZ_CP045205.1 | Citrobacter telavivensis |
| 116 | 3421411 | 3421704 | - | NZ_LT556085.1 | Citrobacter amalonaticus |
| 117 | 3106135 | 3106428 | - | NZ_CP020388.1 | Pluralibacter gergoviae |
| 118 | 2788436 | 2788729 | + | NZ_CP045845.1 | Kluyvera intermedia |
| 119 | 2528259 | 2528564 | + | NZ_CP038853.1 | Pantoea vagans |
| 120 | 1466828 | 1467124 | - | NZ_CP065534.1 | Lonsdalea populi |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NZ_CP011118.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF06429.15 | 0.97 | 116 | 2484 | opposite-strand | Flagellar basal body rod FlgEFG protein C-terminal |
| 2 | PF07559.16 | 0.97 | 116 | 2484 | opposite-strand | Flagellar basal body protein FlaE |
| 3 | PF00460.22 | 1.0 | 119 | 1353.5 | opposite-strand | Flagella basal body rod protein |
| 4 | PF03963.16 | 0.97 | 116 | 1764 | opposite-strand | Flagellar hook capping protein - N-terminal region |
| 5 | PF13860.8 | 0.97 | 116 | 1764 | opposite-strand | FlgD Ig-like domain |
| 6 | PF13861.8 | 0.98 | 117 | 1764.0 | opposite-strand | FlgD Tudor-like domain |
| 7 | PF13144.8 | 1.0 | 119 | 105.5 | same-strand | Chaperone for flagella basal body P-ring formation |
| 8 | PF17656.3 | 0.83 | 99 | 123.0 | same-strand | FlgA N-terminal domain |
| 9 | PF08666.14 | 0.98 | 117 | 105.5 | same-strand | SAF domain |
| 10 | PF05130.14 | 0.98 | 117 | 5.0 | same-strand | FlgN protein |
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