Result : EXP02254
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | EXP02254 |
| NCBI Accession ID | NC_009641.1 |
| Organism | Staphylococcus aureus subsp. aureus str. Newman |
| Left | 1188408 |
| Right | 1188542 |
| Strand | + |
| Nucleotide Sequence | ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGCGCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAATTATTCGGATTCTAA |
| Sequence | MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF |
| Source of smORF | Protein-level |
| Function | The ORF matches to the profile of pfam05480. Profile Description: Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death. |
| Pubmed ID | 34061833 |
| Domain | CDD:398890 |
| Functional Category | Conserved domain based functional assignment |
| Uniprot ID | |
| ORF Length (Amino Acid) | 44 |
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| Conservation Analysis |
No. of Species: 19
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 1088443 | 1088577 | + | NC_007795.1 | Staphylococcus aureus subsp. aureus NCTC 8325 |
| 2 | 1088634 | 1088768 | + | NC_007795.1 | Staphylococcus aureus subsp. aureus NCTC 8325 |
| 3 | 1158955 | 1159089 | + | NZ_LR134304.1 | Staphylococcus schweitzeri |
| 4 | 1159146 | 1159280 | + | NZ_LR134304.1 | Staphylococcus schweitzeri |
| 5 | 1114603 | 1114737 | + | NZ_LT906460.1 | Staphylococcus simiae |
| 6 | 1114779 | 1114913 | + | NZ_LT906460.1 | Staphylococcus simiae |
| 7 | 2305086 | 2305220 | + | NC_022737.1 | Staphylococcus pasteuri SP1 |
| 8 | 2305256 | 2305390 | + | NC_022737.1 | Staphylococcus pasteuri SP1 |
| 9 | 2305442 | 2305576 | + | NC_022737.1 | Staphylococcus pasteuri SP1 |
| 10 | 163128 | 163262 | - | NZ_CP033732.1 | Staphylococcus hominis |
| 11 | 162953 | 163087 | - | NZ_CP033732.1 | Staphylococcus hominis |
| 12 | 162607 | 162741 | - | NZ_CP033732.1 | Staphylococcus hominis |
| 13 | 162776 | 162910 | - | NZ_CP033732.1 | Staphylococcus hominis |
| 14 | 162430 | 162564 | - | NZ_CP033732.1 | Staphylococcus hominis |
| 15 | 1686111 | 1686245 | - | NZ_LR134089.1 | Staphylococcus saprophyticus |
| 16 | 1782708 | 1782842 | - | NZ_CP008724.1 | Staphylococcus xylosus |
| 17 | 1783429 | 1783563 | - | NZ_CP008724.1 | Staphylococcus xylosus |
| 18 | 1783069 | 1783203 | - | NZ_CP008724.1 | Staphylococcus xylosus |
| 19 | 1783248 | 1783382 | - | NZ_CP008724.1 | Staphylococcus xylosus |
| 20 | 1782884 | 1783018 | - | NZ_CP008724.1 | Staphylococcus xylosus |
| 21 | 1676084 | 1676218 | - | NZ_LR134242.1 | Staphylococcus warneri |
| 22 | 1675914 | 1676048 | - | NZ_LR134242.1 | Staphylococcus warneri |
| 23 | 1675362 | 1675496 | - | NZ_LR134242.1 | Staphylococcus warneri |
| 24 | 1675736 | 1675870 | - | NZ_LR134242.1 | Staphylococcus warneri |
| 25 | 1675549 | 1675683 | - | NZ_LR134242.1 | Staphylococcus warneri |
| 26 | 998614 | 998748 | - | NZ_CP018199.1 | Staphylococcus succinus |
| 27 | 998795 | 998929 | - | NZ_CP018199.1 | Staphylococcus succinus |
| 28 | 962339 | 962473 | + | NZ_CP013114.1 | Staphylococcus equorum |
| 29 | 962517 | 962651 | + | NZ_CP013114.1 | Staphylococcus equorum |
| 30 | 962158 | 962292 | + | NZ_CP013114.1 | Staphylococcus equorum |
| 31 | 1802717 | 1802851 | - | NZ_AP018587.1 | Staphylococcus caprae |
| 32 | 1802359 | 1802493 | - | NZ_AP018587.1 | Staphylococcus caprae |
| 33 | 1802547 | 1802681 | - | NZ_AP018587.1 | Staphylococcus caprae |
| 34 | 1802176 | 1802310 | - | NZ_AP018587.1 | Staphylococcus caprae |
| 35 | 818354 | 818488 | + | NZ_CP013911.1 | Staphylococcus haemolyticus |
| 36 | 818737 | 818871 | + | NZ_CP013911.1 | Staphylococcus haemolyticus |
| 37 | 818548 | 818682 | + | NZ_CP013911.1 | Staphylococcus haemolyticus |
| 38 | 818928 | 819062 | + | NZ_CP013911.1 | Staphylococcus haemolyticus |
| 39 | 1641353 | 1641487 | + | NZ_CP066042.1 | Staphylococcus saccharolyticus |
| 40 | 1641548 | 1641682 | + | NZ_CP066042.1 | Staphylococcus saccharolyticus |
| 41 | 1641745 | 1641879 | + | NZ_CP066042.1 | Staphylococcus saccharolyticus |
| 42 | 1219860 | 1219994 | + | NZ_CP033460.1 | Staphylococcus debuckii |
| 43 | 1220053 | 1220190 | + | NZ_CP033460.1 | Staphylococcus debuckii |
| 44 | 468554 | 468688 | + | NZ_CP007601.1 | Staphylococcus capitis subsp. capitis |
| 45 | 468001 | 468135 | + | NZ_CP007601.1 | Staphylococcus capitis subsp. capitis |
| 46 | 468369 | 468503 | + | NZ_CP007601.1 | Staphylococcus capitis subsp. capitis |
| 47 | 468179 | 468313 | + | NZ_CP007601.1 | Staphylococcus capitis subsp. capitis |
| 48 | 1532648 | 1532782 | - | NZ_CP065712.1 | Staphylococcus auricularis |
| 49 | 1532474 | 1532608 | - | NZ_CP065712.1 | Staphylococcus auricularis |
| 50 | 1859954 | 1860088 | - | NZ_CP018776.1 | Staphylococcus condimenti |
| 51 | 1735573 | 1735707 | - | NZ_CP035288.1 | Staphylococcus epidermidis |
| 52 | 1735383 | 1735517 | - | NZ_CP035288.1 | Staphylococcus epidermidis |
| 53 | 1735759 | 1735893 | - | NZ_CP035288.1 | Staphylococcus epidermidis |
| 54 | 1735949 | 1736080 | - | NZ_CP035288.1 | Staphylococcus epidermidis |
| 55 | 913403 | 913534 | + | NC_014925.1 | Staphylococcus pseudintermedius HKU10-03 |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NC_022737.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF05480.13 | 0.84 | 16 | 63.0 | same-strand | Phenol-soluble modulin beta protein |
| 2 | PF13419.8 | 0.89 | 17 | 325.5 | same-strand | Haloacid dehalogenase-like hydrolase |
| 3 | PF00702.28 | 0.68 | 13 | 472.5 | same-strand | haloacid dehalogenase-like hydrolase |
| 4 | PF10079.11 | 0.89 | 17 | 1746.5 | same-strand | Bacillithiol biosynthesis BshC |
| 5 | PF02381.20 | 0.89 | 17 | 3400 | same-strand | MraZ protein, putative antitoxin-like |
| 6 | PF01795.21 | 0.63 | 12 | 3764.5 | same-strand | MraW methylase family |
| 7 | PF13242.8 | 0.63 | 12 | 325 | same-strand | HAD-hyrolase-like |
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