Result : SHP2
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | SHP2 |
| NCBI Accession ID | WP_142353550.1 |
| Organism | Streptococcus pyogenes |
| Left | |
| Right | |
| Strand | |
| Nucleotide Sequence | |
| Sequence | MKKVNKALFFTLIMDILIIVGG |
| Source of smORF | Literature-mining |
| Function | Pheromone promoting biogenesis of biofilms by counteracting the role of RopB. Secreted propeptides are processed and imported into cytoplasm to interact with Rgg receptors. |
| Pubmed ID | 21829369 |
| Domain | |
| Functional Category | Quorum sensing |
| Uniprot ID | |
| ORF Length (Amino Acid) | 22 |
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| Conservation Analysis |
No. of Species: 4
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 404035 | 404103 | - | NZ_CP010450.1 | Streptococcus pyogenes |
| 2 | 1447618 | 1447686 | + | NZ_LR134512.1 | Streptococcus agalactiae |
| 3 | 533844 | 533912 | - | NZ_LR594046.1 | Streptococcus dysgalactiae |
| 4 | 61249 | 61317 | + | NZ_LR134293.1 | Streptococcus canis |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NZ_LR134512.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF01381.24 | 1.0 | 4 | 88.0 | opposite-strand | Helix-turn-helix |
| 2 | PF13560.8 | 1.0 | 4 | 88.0 | opposite-strand | Helix-turn-helix domain |
| 3 | PF01149.26 | 1.0 | 4 | 1115.0 | opposite-strand | Formamidopyrimidine-DNA glycosylase N-terminal domain |
| 4 | PF06831.16 | 1.0 | 4 | 1115.0 | opposite-strand | Formamidopyrimidine-DNA glycosylase H2TH domain |
| 5 | PF06827.16 | 1.0 | 4 | 1115.0 | opposite-strand | Zinc finger found in FPG and IleRS |
| 6 | PF01121.22 | 1.0 | 4 | 1922.5 | opposite-strand | Dephospho-CoA kinase |
| 7 | PF00005.29 | 0.75 | 3 | 2693 | opposite-strand | ABC transporter |
| 8 | PF01841.21 | 0.75 | 3 | 66 | same-strand | Transglutaminase-like superfamily |
++ More..