Result : PeTrpL
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | PeTrpL |
| NCBI Accession ID | WP_202618528.1 |
| Organism | Sinorhizobium meliloti |
| Left | |
| Right | |
| Strand | |
| Nucleotide Sequence | |
| Sequence | MTSARNISIWWWAR |
| Source of smORF | Literature-mining |
| Function | It is a trans-acting peptide that acts by regulating the expression of multidrug resistance operon. SmeAB codes for the multidrug resistance pump and SmeR represses it. It has been found that when the bacterium is exposed to antibiotics, peTrpL destabilises SmeR RNA. SmeR RNA coimmunoprecipitates with peTrpL in Antibiotic Dependent Ribonucleoprotein Complexes (ARNP) which also house SmeR antisense RNA. |
| Pubmed ID | 32546623 |
| Domain | |
| Functional Category | Regulator |
| Uniprot ID | P18854 |
| ORF Length (Amino Acid) | 14 |
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| Conservation Analysis |
No. of Species: 5
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 2364848 | 2364892 | - | NZ_CP023067.1 | Ensifer sojae CCBAU 05684 |
| 2 | 2527619 | 2527663 | - | NZ_CP015880.1 | Ensifer adhaerens |
| 3 | 3182159 | 3182203 | - | NZ_CP041238.1 | Ensifer mexicanus |
| 4 | 2367533 | 2367577 | - | NZ_CP034909.1 | Ensifer alkalisoli |
| 5 | 2581684 | 2581728 | - | NZ_CP029451.1 | Sinorhizobium fredii CCBAU 25509 |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NZ_CP029451.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF04955.14 | 0.6 | 3 | 4550 | opposite-strand | HupE / UreJ protein |
| 2 | PF14489.8 | 1.0 | 5 | 3525 | same-strand | QueF-like protein |
| 3 | PF01545.23 | 1.0 | 5 | 2486 | same-strand | Cation efflux family |
| 4 | PF16916.7 | 1.0 | 5 | 2486 | same-strand | Dimerisation domain of Zinc Transporter |
| 5 | PF00425.20 | 1.0 | 5 | 114 | same-strand | chorismate binding enzyme |
| 6 | PF00117.30 | 1.0 | 5 | 114 | same-strand | Glutamine amidotransferase class-I |
| 7 | PF04715.15 | 1.0 | 5 | 114 | same-strand | Anthranilate synthase component I, N terminal region |
| 8 | PF06904.14 | 1.0 | 5 | 2498 | opposite-strand | Extensin-like protein C-terminus |
| 9 | PF09351.12 | 1.0 | 5 | 3630 | opposite-strand | Domain of unknown function (DUF1993) |
| 10 | PF01268.21 | 1.0 | 5 | 4321 | same-strand | Formate--tetrahydrofolate ligase |
| 11 | PF00593.26 | 0.6 | 3 | 125 | same-strand | TonB dependent receptor |
| 12 | PF07715.17 | 0.6 | 3 | 125 | same-strand | TonB-dependent Receptor Plug Domain |
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