Result : Q9CG51
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | D-alanyl carrier protein (DCP) (D-alanine--poly(phosphoribitol) ligase subunit 2) |
| NCBI Accession ID | AE005176.1 |
| Organism | Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis) |
| Left | 1290260 |
| Right | 1290499 |
| Strand | - |
| Nucleotide Sequence | ATGAAAGAACAAATTTTTGATATTATCGAAACCGTATCAGGCACAGACGAATTCCGTGAAGACTTAGACATGGATTTATTTGAAGAAGGAATTCTTGATTCAATGAGAGCCATCATGCTCATTGTTGAATTAGAAGGCGCTTTTGATATCAGTCTTCCACCATCAGAAATGGACCGTGAAGATTGGAATACAGCAAATAAAATAGCAGCACGCGTTCAGGAAAAAAAGGATGAAAATTAA |
| Sequence | MKEQIFDIIETVSGTDEFREDLDMDLFEEGILDSMRAIMLIVELEGAFDISLPPSEMDREDWNTANKIAARVQEKKDEN |
| Source of smORF | Swiss-Prot |
| Function | Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. {ECO:0000255|HAMAP-Rule:MF_00565}. |
| Pubmed ID | 11337471 |
| Domain | CDD:415812 |
| Functional Category | Others |
| Uniprot ID | Q9CG51 |
| ORF Length (Amino Acid) | 79 |
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| Conservation Analysis |
No. of Species: 13
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 1269715 | 1269954 | - | NC_022369.1 | Lactococcus lactis subsp. cremoris KW2 |
| 2 | 876491 | 876730 | - | NZ_CP032627.1 | Lactococcus allomyrinae |
| 3 | 1229532 | 1229771 | - | NZ_CP070872.1 | Lactococcus taiwanensis |
| 4 | 1334983 | 1335225 | - | NZ_CP065637.1 | Lactococcus garvieae |
| 5 | 2753207 | 2753440 | - | NZ_CP023011.2 | Enterococcus hirae |
| 6 | 872908 | 873144 | + | NZ_AP022822.1 | Enterococcus saigonensis |
| 7 | 1987976 | 1988209 | - | NC_020207.1 | Enterococcus faecium ATCC 8459 = NRRL B-2354 |
| 8 | 2045677 | 2045910 | - | NZ_CP065211.1 | Enterococcus lactis |
| 9 | 1164152 | 1164361 | - | NZ_CP012034.1 | Companilactobacillus ginsenosidimutans |
| 10 | 624148 | 624342 | + | NC_012924.1 | Streptococcus suis SC84 |
| 11 | 1400608 | 1400802 | - | NZ_AP018400.1 | Streptococcus ruminantium |
| 12 | 247814 | 248008 | + | NZ_CP029491.1 | Streptococcus sobrinus |
| 13 | 1927072 | 1927296 | + | NZ_CP024699.1 | Fusobacterium pseudoperiodonticum |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NC_022369.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF04914.14 | 1.0 | 13 | -7 | same-strand | DltD protein |
| 2 | PF00501.30 | 1.0 | 13 | 1255 | same-strand | AMP-binding enzyme |
| 3 | PF13193.8 | 1.0 | 13 | 1255 | same-strand | AMP-binding enzyme C-terminal domain |
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