Result : Q9CCH9
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Biotinylated protein TB7.3 homolog |
| NCBI Accession ID | |
| Organism | Mycobacterium leprae (strain TN) |
| Left | |
| Right | |
| Strand | |
| Nucleotide Sequence | |
| Sequence | MAEDVRAEIVASVLEVVVSEGDQIGKGDVLVLLESMKMEIPVLAGVAGIVSKVSVSVGDVIQAGDLIAVIS |
| Source of smORF | Swiss-Prot |
| Function | The ORF matches to the profile of cl11404. Profile Description: N/A. HlyD_D4 is the long alpha-hairpin domain in the centre of CusB or HlyD proteins. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons. HlyD_D4 is thought to interact with the alpha-helical tunnels of the corresponding outer-membrane channels, ie the periplasmic domain of CusC. |
| Pubmed ID | 11234002 |
| Domain | CDD:416260 |
| Functional Category | Others |
| Uniprot ID | Q9CCH9 |
| ORF Length (Amino Acid) | 71 |
++ More..
| Conservation Analysis |
No. of Species: 165
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 930725 | 930940 | + | NZ_CP029543.1 | Mycobacterium leprae |
| 2 | 491655 | 491870 | + | NZ_AP022581.1 | Mycobacterium lacus |
| 3 | 5061820 | 5062035 | - | NZ_AP022574.1 | Mycolicibacterium psychrotolerans |
| 4 | 4823237 | 4823452 | + | NZ_AP022569.1 | Mycobacterium cookii |
| 5 | 1080164 | 1080379 | + | NZ_CP011883.2 | Mycobacterium haemophilum DSM 44634 |
| 6 | 2512428 | 2512643 | - | NZ_AP022608.1 | Mycolicibacterium gadium |
| 7 | 5874978 | 5875193 | + | NZ_AP022601.1 | Mycobacterium gallinarum |
| 8 | 5155544 | 5155759 | - | NZ_AP022560.1 | Mycolicibacterium moriokaense |
| 9 | 4093000 | 4093215 | - | NZ_CP009360.4 | Mycobacterium avium subsp. hominissuis |
| 10 | 2677021 | 2677236 | - | NZ_AP022575.1 | Mycobacterium shinjukuense |
| 11 | 1000087 | 1000302 | + | NZ_AP022613.1 | Mycobacterium conspicuum |
| 12 | 1528339 | 1528554 | + | NZ_LR134356.1 | Mycolicibacterium aurum |
| 13 | 5891912 | 5892127 | - | NZ_AP022598.1 | Mycolicibacterium parafortuitum |
| 14 | 17134 | 17349 | + | NZ_AP022582.1 | Mycobacterium seoulense |
| 15 | 5525776 | 5525991 | + | NZ_AP022582.1 | Mycobacterium seoulense |
| 16 | 5184205 | 5184420 | + | NZ_AP022573.1 | Mycobacterium saskatchewanense |
| 17 | 2147936 | 2148151 | + | NZ_AP022570.1 | Mycolicibacterium poriferae |
| 18 | 4248351 | 4248566 | - | NC_016946.1 | Mycobacterium intracellulare ATCC 13950 |
| 19 | 4366699 | 4366914 | - | NC_016948.1 | Mycobacterium paraintracellulare |
| 20 | 3024266 | 3024481 | + | NZ_AP022583.1 | Mycobacterium noviomagense |
| 21 | 4109400 | 4109615 | - | NZ_CP023147.1 | Mycobacterium marseillense |
| 22 | 5332614 | 5332829 | + | NZ_AP022619.1 | Mycobacterium paraseoulense |
| 23 | 2555582 | 2555797 | - | NZ_AP022587.1 | Mycobacterium stomatepiae |
| 24 | 1332063 | 1332278 | - | NZ_AP022568.1 | Mycobacterium simiae |
| 25 | 2897390 | 2897605 | - | NZ_AP022563.1 | Mycolicibacterium duvalii |
| 26 | 1565578 | 1565793 | + | NZ_CP011491.1 | Mycolicibacterium vaccae 95051 |
| 27 | 1891584 | 1891799 | + | NC_008726.1 | Mycolicibacterium vanbaalenii PYR-1 |
| 28 | 1395173 | 1395388 | + | NZ_LR130759.1 | Mycobacterium basiliense |
| 29 | 2007237 | 2007452 | - | NZ_AP022593.1 | Mycolicibacterium arabiense |
| 30 | 1656240 | 1656455 | + | NZ_AP018410.1 | Mycobacterium pseudoshottsii JCM 15466 |
| 31 | 2868509 | 2868724 | + | NZ_AP022588.1 | Mycolicibacterium sediminis |
| 32 | 3046582 | 3046797 | + | NZ_CP058277.1 | Mycobacterium marinum |
| 33 | 5763423 | 5763638 | - | NZ_AP022572.1 | Mycobacterium shottsii |
| 34 | 746986 | 747201 | - | NZ_AP022599.1 | Mycolicibacterium pulveris |
| 35 | 2253250 | 2253465 | - | NZ_AP022576.1 | Mycobacterium florentinum |
| 36 | 3702546 | 3702761 | - | NZ_AP024310.1 | Mycobacterium heckeshornense |
| 37 | 3660424 | 3660639 | + | NZ_AP022600.1 | Mycolicibacterium tokaiense |
| 38 | 4725597 | 4725812 | + | NC_022663.1 | Mycobacterium kansasii ATCC 12478 |
| 39 | 3597551 | 3597766 | - | NC_000962.3 | Mycobacterium tuberculosis H37Rv |
| 40 | 3652282 | 3652497 | - | NC_015848.1 | Mycobacterium canettii CIPT 140010059 |
| 41 | 3002415 | 3002630 | - | NZ_AP022614.1 | Mycobacterium parmense |
| 42 | 254454 | 254669 | - | NZ_AP022606.1 | Mycobacterium branderi |
| 43 | 890182 | 890397 | - | NZ_AP022615.1 | Mycobacterium heidelbergense |
| 44 | 1306285 | 1306500 | + | NZ_AP018164.1 | Mycobacterium shigaense |
| 45 | 1313652 | 1313867 | + | NZ_LT906483.1 | Mycolicibacterium thermoresistibile |
| 46 | 5865175 | 5865390 | + | NZ_AP022590.1 | Mycobacterium mantenii |
| 47 | 1599449 | 1599664 | + | NZ_AP022610.1 | Mycolicibacterium madagascariense |
| 48 | 2910542 | 2910757 | - | NZ_AP022586.1 | Mycolicibacterium litorale |
| 49 | 5581500 | 5581715 | + | NZ_AP022620.1 | Mycolicibacterium anyangense |
| 50 | 1612182 | 1612397 | + | NZ_CP025546.1 | Mycobacterium paragordonae |
| 51 | 6291935 | 6292150 | - | NZ_CP012150.1 | Mycobacterium goodii |
| 52 | 937848 | 938063 | + | NZ_AP022605.1 | Mycobacterium doricum |
| 53 | 2810666 | 2810881 | + | NZ_CP043474.1 | Mycobacterium grossiae |
| 54 | 3918222 | 3918437 | + | NZ_AP022596.1 | Mycolicibacterium helvum |
| 55 | 597075 | 597290 | + | NZ_LR026975.1 | Mycolicibacterium hassiacum DSM 44199 |
| 56 | 5273202 | 5273417 | - | NZ_CP020809.1 | Mycobacterium dioxanotrophicus |
| 57 | 4932347 | 4932562 | + | NZ_AP022567.1 | Mycolicibacterium mageritense |
| 58 | 3609775 | 3609990 | - | NZ_AP022612.1 | Mycolicibacterium confluentis |
| 59 | 1394307 | 1394522 | + | NZ_AP022561.1 | Mycolicibacterium aichiense |
| 60 | 1945035 | 1945250 | + | NZ_CP011269.1 | Mycolicibacterium fortuitum |
| 61 | 3364349 | 3364564 | - | NZ_AP022617.1 | Mycolicibacterium monacense |
| 62 | 1973960 | 1974175 | - | NZ_AP022565.1 | Mycolicibacterium alvei |
| 63 | 5761803 | 5762018 | - | NZ_AP022579.1 | Mycolicibacterium boenickei |
| 64 | 2490845 | 2491060 | - | NZ_AP022609.1 | Mycolicibacter hiberniae |
| 65 | 2064192 | 2064407 | + | NZ_LN831039.1 | Mycolicibacterium smegmatis |
| 66 | 3336084 | 3336299 | + | NZ_AP022562.1 | Mycobacterium novum |
| 67 | 5643863 | 5644078 | + | NZ_AP022616.1 | Mycolicibacterium phocaicum |
| 68 | 1686346 | 1686561 | - | NZ_AP022577.1 | Mycolicibacterium aubagnense |
| 69 | 4151342 | 4151557 | - | NZ_CP062008.1 | Mycolicibacterium mucogenicum DSM 44124 |
| 70 | 3049972 | 3050187 | - | NZ_LT906469.1 | Mycolicibacter terrae |
| 71 | 323256 | 323471 | - | NZ_AP022595.1 | Mycolicibacterium sarraceniae |
| 72 | 3613064 | 3613279 | - | NZ_LR134355.1 | Mycolicibacterium chitae |
| 73 | 3141245 | 3141460 | - | NC_015576.1 | Mycolicibacter sinensis |
| 74 | 632823 | 633038 | - | NZ_AP022589.1 | Mycolicibacter minnesotensis |
| 75 | 3568988 | 3569203 | - | NZ_LT906450.1 | Rhodococcus rhodochrous |
| 76 | 3909860 | 3910075 | - | NZ_CP022208.1 | Rhodococcus pyridinivorans |
| 77 | 3661939 | 3662112 | - | NZ_AP018165.1 | [Mycobacterium] stephanolepidis |
| 78 | 2468414 | 2468629 | - | NZ_CP061007.1 | Saccharopolyspora spinosa |
| 79 | 8479839 | 8480015 | + | NZ_CP061007.1 | Saccharopolyspora spinosa |
| 80 | 7561596 | 7561811 | + | NZ_CP031142.1 | Saccharopolyspora pogona |
| 81 | 2307763 | 2307978 | + | NZ_AP023172.1 | Rhodococcus qingshengii |
| 82 | 4022886 | 4023059 | - | NZ_CP011530.1 | Mycobacteroides immunogenum |
| 83 | 3390477 | 3390659 | - | NZ_CP024633.1 | Mycobacteroides salmoniphilum |
| 84 | 3594435 | 3594608 | - | NZ_CP014955.1 | Mycobacteroides abscessus |
| 85 | 3322064 | 3322237 | - | NZ_CP010271.1 | Mycobacteroides saopaulense |
| 86 | 3624225 | 3624398 | - | NZ_CP007220.1 | Mycobacteroides chelonae CCUG 47445 |
| 87 | 2730096 | 2730311 | - | NZ_CP048813.1 | Rhodococcus triatomae |
| 88 | 1684250 | 1684465 | + | NZ_AP022618.1 | Mycolicibacterium insubricum |
| 89 | 4251675 | 4251890 | + | NZ_LS483468.1 | Rhodococcus coprophilus |
| 90 | 3850592 | 3850807 | - | NC_015564.1 | Hoyosella subflava DQS3-9A1 |
| 91 | 1970882 | 1971097 | - | NZ_AP022603.1 | Mycolicibacterium fallax |
| 92 | 3726582 | 3726773 | - | NZ_CP027793.1 | Rhodococcus hoagii |
| 93 | 1067430 | 1067645 | + | NZ_CP015453.1 | Dietzia psychralcaliphila |
| 94 | 1127151 | 1127366 | + | NZ_CP015449.1 | Dietzia lutea |
| 95 | 16762 | 16941 | - | NZ_CP015235.1 | Rhodococcus fascians D188 |
| 96 | 8970351 | 8970530 | - | NC_013131.1 | Catenulispora acidiphila DSM 44928 |
| 97 | 3747558 | 3747779 | - | NC_013441.1 | Gordonia bronchialis DSM 43247 |
| 98 | 4969221 | 4969436 | - | NZ_CP015163.1 | Amycolatopsis albispora |
| 99 | 2216107 | 2216322 | + | NZ_CP027114.1 | Gordonia alkanivorans |
| 100 | 4889745 | 4889960 | - | NZ_CP059694.1 | Gordonia rubripertincta |
| 101 | 3805778 | 3805999 | - | NC_016906.1 | Gordonia polyisoprenivorans VH2 |
| 102 | 8551143 | 8551358 | + | NZ_AP022870.1 | Phytohabitans flavus |
| 103 | 4565647 | 4565862 | - | NZ_CP045309.1 | Micromonospora terminaliae |
| 104 | 4447675 | 4447890 | + | NZ_CP061725.1 | Micromonospora craniellae |
| 105 | 1559925 | 1560140 | + | NC_013235.1 | Nakamurella multipartita DSM 44233 |
| 106 | 3999430 | 3999645 | - | NZ_CP045929.1 | Saccharopolyspora coralli |
| 107 | 5656386 | 5656601 | + | NZ_CP033972.1 | Gordonia insulae |
| 108 | 5685910 | 5686125 | - | NZ_CP016353.1 | Prauserella marina |
| 109 | 5905719 | 5905934 | - | NC_014391.1 | Micromonospora aurantiaca ATCC 27029 |
| 110 | 580653 | 580841 | + | NC_008578.1 | Acidothermus cellulolyticus 11B |
| 111 | 6328039 | 6328254 | - | NZ_CP058322.1 | Micromonospora carbonacea |
| 112 | 4662517 | 4662732 | + | NZ_AP022871.1 | Phytohabitans suffuscus |
| 113 | 7422400 | 7422615 | - | NZ_CP023865.1 | Actinoplanes teichomyceticus ATCC 31121 |
| 114 | 9546624 | 9546803 | - | NZ_CP045572.1 | Nonomuraea nitratireducens |
| 115 | 4256856 | 4257071 | - | NC_009380.1 | Salinispora tropica CNB-440 |
| 116 | 3240506 | 3240727 | - | NZ_CP011853.1 | Gordonia phthalatica |
| 117 | 7916906 | 7917121 | - | NC_017093.1 | Actinoplanes missouriensis 431 |
| 118 | 3365877 | 3366092 | + | NZ_CP047156.1 | Epidermidibacterium keratini |
| 119 | 4515343 | 4515573 | - | NC_007777.1 | Frankia casuarinae |
| 120 | 4865773 | 4865988 | - | NZ_AP023355.1 | Actinocatenispora thailandica |
| 121 | 8314545 | 8314760 | - | NC_022657.1 | Actinoplanes friuliensis DSM 7358 |
| 122 | 10022820 | 10023035 | - | NZ_CP034550.1 | Saccharothrix syringae |
| 123 | 4253062 | 4253241 | - | NC_013510.1 | Thermomonospora curvata DSM 43183 |
| 124 | 4509917 | 4510132 | + | NZ_CP031264.1 | Streptacidiphilus bronchialis |
| 125 | 4766089 | 4766304 | - | NC_006361.1 | Nocardia farcinica IFM 10152 |
| 126 | 1495708 | 1495923 | + | NZ_AP023396.1 | Nocardia wallacei |
| 127 | 974528 | 974707 | + | NZ_CP022752.1 | Actinopolyspora erythraea |
| 128 | 989333 | 989560 | + | NZ_CP045737.1 | Aeromicrobium yanjiei |
| 129 | 6635172 | 6635387 | - | NZ_AP017900.1 | Nocardia seriolae |
| 130 | 9179043 | 9179231 | - | NC_013595.1 | Streptosporangium roseum DSM 43021 |
| 131 | 3178348 | 3178563 | + | NZ_CP026746.1 | Nocardia cyriacigeorgica |
| 132 | 6512449 | 6512679 | - | NC_008278.1 | Frankia alni ACN14a |
| 133 | 8875907 | 8876122 | - | NZ_CP007155.1 | Kutzneria albida DSM 43870 |
| 134 | 7203312 | 7203485 | - | NC_009142.1 | Saccharopolyspora erythraea NRRL 2338 |
| 135 | 1082950 | 1083177 | + | NZ_CP026952.1 | Aeromicrobium chenweiae |
| 136 | 5506989 | 5507204 | - | NC_013947.1 | Stackebrandtia nassauensis DSM 44728 |
| 137 | 543847 | 544101 | + | NC_015312.1 | Pseudonocardia dioxanivorans CB1190 |
| 138 | 2208235 | 2208408 | + | NZ_CP016279.1 | Streptomyces griseochromogenes |
| 139 | 564510 | 564725 | - | NZ_AP023439.1 | Streptomyces tuirus |
| 140 | 3358079 | 3358294 | - | NZ_CP029146.1 | Rhodococcus ruber |
| 141 | 1123020 | 1123235 | + | NZ_CP015961.1 | Dietzia timorensis |
| 142 | 3426733 | 3426921 | - | NC_014165.1 | Thermobispora bispora DSM 43833 |
| 143 | 8133664 | 8133879 | + | NZ_CP022088.2 | Nocardia brasiliensis |
| 144 | 6300429 | 6300644 | - | NZ_LR134352.1 | Nocardia asteroides |
| 145 | 2042344 | 2042529 | + | NZ_CP060713.1 | Nocardioides mesophilus |
| 146 | 5264458 | 5264643 | - | NZ_CP009896.1 | Pimelobacter simplex |
| 147 | 1733593 | 1733805 | + | NZ_CP022753.1 | Nocardiopsis gilva YIM 90087 |
| 148 | 5424588 | 5424803 | - | NZ_CP018082.1 | Nocardia mangyaensis |
| 149 | 876161 | 876376 | + | NZ_CP041695.1 | Nocardia otitidiscaviarum |
| 150 | 5917688 | 5917882 | - | NC_013729.1 | Kribbella flavida DSM 17836 |
| 151 | 4400104 | 4400277 | - | NC_013757.1 | Geodermatophilus obscurus DSM 43160 |
| 152 | 2555694 | 2555888 | - | NZ_CP043661.1 | Kribbella qitaiheensis |
| 153 | 2413213 | 2413389 | - | NZ_CP044548.2 | Janibacter melonis |
| 154 | 2495049 | 2495270 | + | NZ_CP011807.3 | Pandoraea faecigallinarum |
| 155 | 3362803 | 3363021 | + | NZ_CP013290.1 | Janibacter indicus |
| 156 | 2316066 | 2316245 | - | NZ_CP038267.1 | Nocardioides euryhalodurans |
| 157 | 1028166 | 1028366 | + | NZ_CP060783.1 | Diaphorobacter aerolatus |
| 158 | 1631800 | 1632021 | + | NZ_CP017703.1 | Aeribacillus pallidus |
| 159 | 1622669 | 1622869 | + | NZ_CP038436.1 | Nocardioides seonyuensis |
| 160 | 3487030 | 3487203 | - | NZ_CP047385.1 | Pandoraea fibrosis |
| 161 | 2693689 | 2693862 | + | NZ_CP011253.3 | Pandoraea oxalativorans |
| 162 | 4918043 | 4918264 | + | NC_023018.2 | Pandoraea pnomenusa |
| 163 | 2783334 | 2783507 | + | NZ_CP010897.2 | Pandoraea vervacti |
| 164 | 998749 | 998976 | + | NC_014666.1 | Frankia inefficax |
| 165 | 1462850 | 1463023 | + | NZ_CP015079.1 | Nocardioides dokdonensis FR1436 |
| 166 | 2070796 | 2070987 | - | NC_007426.1 | Natronomonas pharaonis DSM 2160 |
| 167 | 2865933 | 2866115 | - | NZ_CP044344.1 | Nocardioides cynanchi |
++ More..
| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NZ_AP022581.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF12282.10 | 0.76 | 125 | 33.0 | same-strand | Signal transduction histidine kinase |
| 2 | PF07568.14 | 0.75 | 124 | 33 | same-strand | Histidine kinase |
| 3 | PF02518.28 | 0.76 | 126 | 33 | same-strand | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
| 4 | PF07536.16 | 0.65 | 107 | 33.0 | same-strand | HWE histidine kinase |
| 5 | PF08448.12 | 0.65 | 107 | 33.0 | same-strand | PAS fold |
| 6 | PF02467.18 | 0.79 | 130 | 1627 | opposite-strand | Transcription factor WhiB |
| 7 | PF04542.16 | 0.83 | 137 | 623 | same-strand | Sigma-70 region 2 |
| 8 | PF08281.14 | 0.83 | 137 | 623 | same-strand | Sigma-70, region 4 |
| 9 | PF04545.18 | 0.83 | 137 | 626.5 | same-strand | Sigma-70, region 4 |
| 10 | PF13490.8 | 0.82 | 136 | 316 | same-strand | Putative zinc-finger |
| 11 | PF00781.26 | 0.7 | 115 | 2159.0 | opposite-strand | Diacylglycerol kinase catalytic domain |
++ More..