| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Toxin RelE1 |
| NCBI Accession ID | AE005673.1 |
| Organism | Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) |
| Left | 890690 |
| Right | 890971 |
| Strand | - |
| Nucleotide Sequence | TTGACCTTCACGGTTTTGGTATCCGTTCGGGCCAAGAGAGACTTCAACCGTCTCATCGTCTGGCTTGTGGAGCGCGACCCCCGAGCAGCGGCTAGACTGGGCCCACTTCTGGAGGCCGCCCTCGACAGTTTGACCGAGGCGCCATCGCGAGGTCGCTCGGTTGGTCCCACCACCCGCGAGATCAGCATTCCTTTTGGTCAGAGCGCCTATGTGATCCGCTACCGGCTCCTCGGCTCCAGCGTACATGTCACCCGGATCTGGCACGGCCTTGAGCAAAGGTAG |
| Sequence | MTFTVLVSVRAKRDFNRLIVWLVERDPRAAARLGPLLEAALDSLTEAPSRGRSVGPTTREISIPFGQSAYVIRYRLLGSSVHVTRIWHGLEQR |
| Source of smORF | Swiss-Prot |
| Function | Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin RelB1 but no other ParD or RelB antitoxin. {ECO:0000269|Pubmed:20487277}. |
| Pubmed ID | 11259647 15718296 20487277 |
| Domain | CDD:419697 |
| Functional Category | Toxin_type_2 |
| Uniprot ID | Q9AA09 |
| ORF Length (Amino Acid) | 93 |
| Conservation Analysis |
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 916721 | 917002 | - | NC_011916.1 | Caulobacter vibrioides NA1000 |
| 2 | 2336263 | 2336544 | - | NZ_CP026100.1 | Caulobacter flavus |
| Neighborhood Conservation Analysis |
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF00171.24 | 1.0 | 2 | 300.0 | same-strand | Aldehyde dehydrogenase family |
| 2 | PF01619.20 | 1.0 | 2 | 300.0 | same-strand | Proline dehydrogenase |
| 3 | PF14850.8 | 1.0 | 2 | 300.0 | same-strand | DNA-binding domain of Proline dehydrogenase |
| 4 | PF01037.23 | 1.0 | 2 | 3835.0 | opposite-strand | Lrp/AsnC ligand binding domain |
| 5 | PF13412.8 | 1.0 | 2 | 3835.0 | opposite-strand | Winged helix-turn-helix DNA-binding |
| 6 | PF13404.8 | 1.0 | 2 | 3835.0 | opposite-strand | AsnC-type helix-turn-helix domain |