Protein name |
Toxin ParE1 |
NCBI Accession ID |
AE005673.1 |
Organism |
Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) |
Left |
968678 |
Right |
968968 |
Strand |
- |
Nucleotide Sequence |
ATGAAGCCCTATCGGCTATCCCGTCGCGCCAAGGCCGACCTCGATGACATCTGGACCTATTCAGAGCAGCGATGGGGCGTTGAACAAGCCGCCGACTACGCCCGTGAACTGCAGGCCACCATCGAGATGATCGCTGAACATCCGGGTATGGGACAGCCGGATGAAAACCTCCGCGCGGGCTACAGGCGATGCGCCAGCGGCTCGCACGTGGTCTTTTACCGCGTCGGCGTGCGGGTCGAGATTATCCGCGTGCTACACCAAAGCATGAACGCCAGGGCTCACCTTGGCTGA |
Sequence |
MKPYRLSRRAKADLDDIWTYSEQRWGVEQAADYARELQATIEMIAEHPGMGQPDENLRAGYRRCASGSHVVFYRVGVRVEIIRVLHQSMNARAHLG |
Source of smORF |
Swiss-Prot |
Function |
Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD1 but no other ParD or RelB antitoxin. Low levels of wild-type toxin in the absence of antitoxin decreases the rate of cell growth, and results in death or loss of colony formation abilities and greatly elongated cells. Low levels of a mutant missing the last 4 residues leads to loss of cell division while cell elongation continues. {ECO:0000269|Pubmed:20487277}. |
Pubmed ID |
11259647
15718296
20487277
20143871
|
Domain |
CDD:419697 |
Functional Category |
Toxin_type_2 |
Uniprot ID |
Q9A9T8
|
ORF Length (Amino Acid) |
96 |