Result : Q8XBW9
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Protein HokE |
| NCBI Accession ID | |
| Organism | Escherichia coli O157:H7 |
| Left | |
| Right | |
| Strand | |
| Nucleotide Sequence | |
| Sequence | MLTKYALVAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVLAYEPKK |
| Source of smORF | Swiss-Prot |
| Function | Toxic component of a type I toxin-antitoxin (TA) system (By similarity). When overexpressed kills cells within minutes; causes collapse of the transmembrane potential and arrest of respiration (By similarity). Its toxic effect is probably neutralized by an antisense antitoxin Sok RNA (By similarity). {ECO:0000250|UniProtKB:P0ACG4}. |
| Pubmed ID | 11206551 11258796 |
| Domain | CDD:421511 |
| Functional Category | Toxin_type_1 |
| Uniprot ID | Q8XBW9 |
| ORF Length (Amino Acid) | 50 |
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| Conservation Analysis |
No. of Species: 25
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 1574962 | 1575114 | - | NZ_CP057657.1 | Escherichia fergusonii |
| 2 | 3850299 | 3850451 | + | NZ_CP057657.1 | Escherichia fergusonii |
| 3 | 511910 | 512062 | + | NC_004337.2 | Shigella flexneri 2a str. 301 |
| 4 | 511407 | 511559 | + | NC_004337.2 | Shigella flexneri 2a str. 301 |
| 5 | 2851185 | 2851337 | - | NC_004337.2 | Shigella flexneri 2a str. 301 |
| 6 | 690842 | 690994 | + | NC_002695.2 | Escherichia coli O157:H7 str. Sakai |
| 7 | 690339 | 690491 | + | NC_002695.2 | Escherichia coli O157:H7 str. Sakai |
| 8 | 3607408 | 3607560 | - | NC_002695.2 | Escherichia coli O157:H7 str. Sakai |
| 9 | 607836 | 607988 | + | NC_000913.3 | Escherichia coli str. K-12 substr. MG1655 |
| 10 | 583107 | 583259 | + | NZ_AP014857.1 | Escherichia albertii |
| 11 | 2817162 | 2817314 | - | NZ_AP014857.1 | Escherichia albertii |
| 12 | 3120594 | 3120746 | - | NZ_CP061527.1 | Shigella dysenteriae |
| 13 | 3133031 | 3133183 | - | NZ_CP061527.1 | Shigella dysenteriae |
| 14 | 3370334 | 3370486 | - | NZ_LR134340.1 | Escherichia marmotae |
| 15 | 639283 | 639435 | + | NC_013716.1 | Citrobacter rodentium ICC168 |
| 16 | 1048024 | 1048176 | + | NZ_CP054254.1 | Klebsiella variicola |
| 17 | 4201495 | 4201647 | - | NC_016845.1 | Klebsiella pneumoniae subsp. pneumoniae HS11286 |
| 18 | 4298098 | 4298250 | - | NZ_CP045205.1 | Citrobacter telavivensis |
| 19 | 1663187 | 1663339 | - | NZ_CP033744.1 | Citrobacter freundii |
| 20 | 1046473 | 1046625 | + | NZ_CP065838.1 | Klebsiella quasipneumoniae |
| 21 | 990102 | 990254 | + | NZ_CP041247.1 | Raoultella electrica |
| 22 | 4377967 | 4378119 | - | NZ_CP051548.1 | Phytobacter diazotrophicus |
| 23 | 1251487 | 1251639 | + | NZ_CP036175.1 | Klebsiella huaxiensis |
| 24 | 4300624 | 4300776 | - | NZ_CP036175.1 | Klebsiella huaxiensis |
| 25 | 249026 | 249160 | + | NZ_CP036175.1 | Klebsiella huaxiensis |
| 26 | 1145480 | 1145632 | + | NZ_CP060111.1 | Klebsiella michiganensis |
| 27 | 4444628 | 4444780 | - | NZ_CP060111.1 | Klebsiella michiganensis |
| 28 | 255572 | 255724 | + | NZ_CP060111.1 | Klebsiella michiganensis |
| 29 | 2392287 | 2392439 | + | NZ_CP054058.1 | Scandinavium goeteborgense |
| 30 | 3595776 | 3595928 | - | NZ_CP013990.1 | Leclercia adecarboxylata |
| 31 | 3579900 | 3580058 | + | NZ_CP027107.1 | Cronobacter sakazakii |
| 32 | 3948996 | 3949154 | - | NZ_CP013940.1 | Cronobacter malonaticus LMG 23826 |
| 33 | 3947842 | 3948000 | - | NZ_CP013940.1 | Cronobacter malonaticus LMG 23826 |
| 34 | 4104933 | 4105091 | - | NZ_CP012257.1 | Cronobacter universalis NCTC 9529 |
| 35 | 4219229 | 4219387 | + | NZ_CP012268.1 | Cronobacter muytjensii ATCC 51329 |
| 36 | 4286344 | 4286502 | - | NZ_CP012266.1 | Cronobacter dublinensis subsp. dublinensis LMG 23823 |
| 37 | 1843461 | 1843619 | + | NZ_CP042941.1 | Atlantibacter hermannii |
| 38 | 1842962 | 1843120 | + | NZ_CP042941.1 | Atlantibacter hermannii |
| 39 | 227753 | 227905 | + | NZ_CP045845.1 | Kluyvera intermedia |
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