Result : Q8VJ53
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Probable transcriptional regulator WhiB7 |
| NCBI Accession ID | |
| Organism | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) |
| Left | |
| Right | |
| Strand | |
| Nucleotide Sequence | |
| Sequence | MSVLTVPRQTPRQRLPVLPCHVGDPDLWFADTPAGLEVAKTLCVSCPIRRQCLAAALQRAEPWGVWGGEIFDQGSIVSHKRPRGRPRKDAVA |
| Source of smORF | Swiss-Prot |
| Function | Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA (By similarity). {ECO:0000250}. |
| Pubmed ID | 12218036 16870781 22829866 |
| Domain | |
| Functional Category | DNA-binding_and_Metal-binding |
| Uniprot ID | Q8VJ53 |
| ORF Length (Amino Acid) | 92 |
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| Conservation Analysis |
No. of Species: 64
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 3568401 | 3568679 | - | NC_000962.3 | Mycobacterium tuberculosis H37Rv |
| 2 | 3623076 | 3623354 | - | NC_015848.1 | Mycobacterium canettii CIPT 140010059 |
| 3 | 1335525 | 1335794 | + | NZ_AP018164.1 | Mycobacterium shigaense |
| 4 | 46766 | 47035 | + | NZ_AP022582.1 | Mycobacterium seoulense |
| 5 | 1303063 | 1303332 | - | NZ_AP022568.1 | Mycobacterium simiae |
| 6 | 2222763 | 2223032 | - | NZ_AP022576.1 | Mycobacterium florentinum |
| 7 | 5731321 | 5731584 | - | NZ_AP022572.1 | Mycobacterium shottsii |
| 8 | 5362195 | 5362467 | + | NZ_AP022619.1 | Mycobacterium paraseoulense |
| 9 | 5895794 | 5896066 | + | NZ_AP022590.1 | Mycobacterium mantenii |
| 10 | 3077857 | 3078120 | + | NZ_CP058277.1 | Mycobacterium marinum |
| 11 | 1688784 | 1689047 | + | NZ_AP018410.1 | Mycobacterium pseudoshottsii JCM 15466 |
| 12 | 860852 | 861118 | - | NZ_AP022615.1 | Mycobacterium heidelbergense |
| 13 | 4080051 | 4080278 | - | NZ_CP023147.1 | Mycobacterium marseillense |
| 14 | 2526334 | 2526603 | - | NZ_AP022587.1 | Mycobacterium stomatepiae |
| 15 | 1426613 | 1426876 | + | NZ_LR130759.1 | Mycobacterium basiliense |
| 16 | 2972953 | 2973219 | - | NZ_AP022614.1 | Mycobacterium parmense |
| 17 | 5215608 | 5215868 | + | NZ_AP022573.1 | Mycobacterium saskatchewanense |
| 18 | 4063743 | 4064015 | - | NZ_CP009360.4 | Mycobacterium avium subsp. hominissuis |
| 19 | 4852118 | 4852381 | + | NZ_AP022569.1 | Mycobacterium cookii |
| 20 | 1110965 | 1111234 | + | NZ_CP011883.2 | Mycobacterium haemophilum DSM 44634 |
| 21 | 750507 | 750776 | + | NZ_CP029543.1 | Mycobacterium leprae |
| 22 | 526280 | 526555 | + | NZ_AP022581.1 | Mycobacterium lacus |
| 23 | 3690593 | 3690874 | + | NZ_AP022600.1 | Mycolicibacterium tokaiense |
| 24 | 4337379 | 4337630 | - | NC_016948.1 | Mycobacterium paraintracellulare |
| 25 | 4219096 | 4219347 | - | NC_016946.1 | Mycobacterium intracellulare ATCC 13950 |
| 26 | 4758094 | 4758357 | + | NC_022663.1 | Mycobacterium kansasii ATCC 12478 |
| 27 | 1641308 | 1641571 | + | NZ_CP025546.1 | Mycobacterium paragordonae |
| 28 | 2645285 | 2645548 | - | NZ_AP022575.1 | Mycobacterium shinjukuense |
| 29 | 3054960 | 3055226 | + | NZ_AP022583.1 | Mycobacterium noviomagense |
| 30 | 3567626 | 3567895 | - | NZ_LR134355.1 | Mycolicibacterium chitae |
| 31 | 3579618 | 3579887 | - | NZ_AP022612.1 | Mycolicibacterium confluentis |
| 32 | 5614988 | 5615257 | + | NZ_AP022620.1 | Mycolicibacterium anyangense |
| 33 | 3811725 | 3811988 | - | NC_015564.1 | Hoyosella subflava DQS3-9A1 |
| 34 | 5722857 | 5723129 | - | NZ_AP022579.1 | Mycolicibacterium boenickei |
| 35 | 605730 | 605957 | - | NZ_AP022589.1 | Mycolicibacter minnesotensis |
| 36 | 280812 | 281042 | - | NZ_AP022595.1 | Mycolicibacterium sarraceniae |
| 37 | 1342353 | 1342646 | + | NZ_LT906483.1 | Mycolicibacterium thermoresistibile |
| 38 | 1984896 | 1985177 | + | NZ_CP011269.1 | Mycolicibacterium fortuitum |
| 39 | 5681004 | 5681234 | + | NZ_AP022616.1 | Mycolicibacterium phocaicum |
| 40 | 1426638 | 1426907 | + | NZ_AP022561.1 | Mycolicibacterium aichiense |
| 41 | 4114281 | 4114544 | - | NZ_CP062008.1 | Mycolicibacterium mucogenicum DSM 44124 |
| 42 | 214019 | 214261 | - | NZ_CP013290.1 | Janibacter indicus |
| 43 | 747700 | 747966 | + | NZ_CP013290.1 | Janibacter indicus |
| 44 | 1649263 | 1649493 | - | NZ_AP022577.1 | Mycolicibacterium aubagnense |
| 45 | 3240920 | 3241189 | + | NZ_CP026746.1 | Nocardia cyriacigeorgica |
| 46 | 6552823 | 6553095 | - | NZ_AP017900.1 | Nocardia seriolae |
| 47 | 4704675 | 4704908 | - | NC_006361.1 | Nocardia farcinica IFM 10152 |
| 48 | 3672601 | 3672867 | - | NZ_AP024310.1 | Mycobacterium heckeshornense |
| 49 | 224207 | 224449 | - | NZ_AP022606.1 | Mycobacterium branderi |
| 50 | 8206005 | 8206235 | + | NZ_CP022088.2 | Nocardia brasiliensis |
| 51 | 5023528 | 5023803 | - | NZ_AP022574.1 | Mycolicibacterium psychrotolerans |
| 52 | 2867670 | 2867957 | - | NZ_AP022563.1 | Mycolicibacterium duvalii |
| 53 | 3316363 | 3316593 | - | NZ_CP029146.1 | Rhodococcus ruber |
| 54 | 2683326 | 2683565 | + | NZ_LN849456.1 | Devriesea agamarum |
| 55 | 2006768 | 2007046 | - | NC_008578.1 | Acidothermus cellulolyticus 11B |
| 56 | 2510121 | 2510363 | - | NZ_CP023564.1 | Brachybacterium ginsengisoli |
| 57 | 3210226 | 3210495 | - | NZ_CP011853.1 | Gordonia phthalatica |
| 58 | 1903773 | 1904039 | + | NZ_CP009896.1 | Pimelobacter simplex |
| 59 | 5751040 | 5751327 | - | NC_013729.1 | Kribbella flavida DSM 17836 |
| 60 | 885206 | 885472 | - | NZ_CP041146.1 | Nocardioides humi |
| 61 | 3424557 | 3424814 | + | NC_009664.2 | Kineococcus radiotolerans SRS30216 = ATCC BAA-149 |
| 62 | 1791066 | 1791341 | + | NZ_CP022295.1 | Nocardioides aromaticivorans |
| 63 | 1136865 | 1137107 | + | NZ_CP039291.1 | Cellulomonas shaoxiangyii |
| 64 | 2762403 | 2762648 | - | NC_014151.1 | Cellulomonas flavigena DSM 20109 |
| 65 | 1070663 | 1070905 | + | NC_015671.1 | Cellulomonas gilvus ATCC 13127 |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NC_000962.3
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF10103.11 | 0.77 | 49 | 2487 | opposite-strand | Zincin-like metallopeptidase |
| 2 | PF03109.18 | 0.84 | 54 | 46.5 | opposite-strand | ABC1 atypical kinase-like domain |
| 3 | PF13245.8 | 0.97 | 62 | 449.0 | same-strand | AAA domain |
| 4 | PF00570.25 | 0.95 | 61 | 434 | same-strand | HRDC domain |
| 5 | PF00462.26 | 0.78 | 50 | 2694.5 | opposite-strand | Glutaredoxin |
| 6 | PF00293.30 | 0.81 | 52 | 3057 | same-strand | NUDIX domain |
| 7 | PF09297.13 | 0.73 | 47 | 3056 | same-strand | NADH pyrophosphatase zinc ribbon domain |
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