| Protein Information | 
| Information Type | Description | 
|---|---|
| Protein name | Broad mercury transporter MerE | 
| NCBI Accession ID | AP000342.1 | 
| Organism | Shigella flexneri | 
| Left | 3818 | 
| Right | 4054 | 
| Strand | + | 
| Nucleotide Sequence | GTGAACGCCCCTGACAAACTGCCGCCCGAGACGCGCCAACCCGTTTCCGGCTACCTGTGGGGTGCGCTGGCCGTGTTGACCTGCCCCTGCCATCTGCCGATTCTCGCCGCCGTGCTGGCCGGGACGACCGCCGGTGCCTTCCTTGGCGAGCATTGGGGTGTTGCCGCGCTCGCGCTGACCGGCTTGTTCGTTCTGGCCGTAACGCGGCTGCTGCGCGCCTTCCGGGGCGGATCATGA | 
| Sequence | MNAPDKLPPETRQPVSGYLWGALAVLTCPCHLPILAAVLAGTTAGAFLGEHWGVAALALTGLFVLAVTRLLRAFRGGS | 
| Source of smORF | Swiss-Prot | 
| Function | Broad mercury transporter that mediates the transport of both CH(3)Hg(I) and Hg(II) across the membrane. {ECO:0000269|Pubmed:19265693}. | 
| Pubmed ID | 19265693 | 
| Domain | CDD:331288 | 
| Functional Category | Others | 
| Uniprot ID | Q7AKA4 | 
| ORF Length (Amino Acid) | 78 | 
| Conservation Analysis | 
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name | 
|---|---|---|---|---|---|
| 1 | 15631 | 15867 | + | NC_016846.1 | Klebsiella pneumoniae subsp. pneumoniae HS11286 | 
| 2 | 916021 | 916257 | - | NC_004757.1 | Nitrosomonas europaea ATCC 19718 | 
| 3 | 821863 | 822099 | - | NZ_CP028901.1 | Algicoccus marinus | 
| 4 | 5612234 | 5612470 | + | NZ_AP017928.1 | Methylocaldum marinum | 
| 5 | 40808 | 41044 | - | NC_008341.1 | Nitrosomonas eutropha C91 | 
| 6 | 49605 | 49841 | - | NZ_CP011599.1 | Phytobacter ursingii | 
| 7 | 87965 | 88201 | + | NZ_CP022359.1 | Shewanella bicestrii | 
| 8 | 207158 | 207394 | - | NZ_CP011601.1 | Phytobacter ursingii | 
| 9 | 112684 | 112920 | - | NZ_CP061512.1 | Mixta calida | 
| 10 | 153078 | 153314 | + | NZ_CP041248.1 | Raoultella electrica | 
| 11 | 87623 | 87859 | - | NZ_CP041248.1 | Raoultella electrica | 
| 12 | 296932 | 297168 | - | NZ_CP029396.2 | Acinetobacter defluvii | 
| 13 | 306615 | 306851 | - | NZ_CP029396.2 | Acinetobacter defluvii | 
| 14 | 1373301 | 1373537 | + | NC_008344.1 | Nitrosomonas eutropha C91 | 
| 15 | 32488 | 32724 | - | NC_008344.1 | Nitrosomonas eutropha C91 | 
| 16 | 161660 | 161896 | + | NZ_CP011600.1 | Phytobacter ursingii | 
| 17 | 314363 | 314599 | - | NZ_CP005961.1 | Pseudomonas mandelii JR-1 | 
| 18 | 157744 | 157980 | + | NZ_CP005961.1 | Pseudomonas mandelii JR-1 | 
| 19 | 323108 | 323344 | - | NZ_CP009365.1 | Pseudomonas soli | 
| 20 | 21323 | 21559 | + | NZ_CP027670.1 | Simplicispira suum | 
| 21 | 1854046 | 1854282 | + | NZ_LR778301.1 | Denitratisoma oestradiolicum | 
| 22 | 68997 | 69233 | - | NZ_CP062807.1 | Cupriavidus basilensis | 
| 23 | 4464 | 4700 | + | NZ_CP032520.1 | Cupriavidus oxalaticus | 
| 24 | 74442 | 74678 | - | NZ_CP032520.1 | Cupriavidus oxalaticus | 
| 25 | 561044 | 561280 | + | NZ_CP032520.1 | Cupriavidus oxalaticus | 
| 26 | 1266359 | 1266595 | - | NC_007953.1 | Paraburkholderia xenovorans LB400 | 
| 27 | 462191 | 462427 | - | NZ_CP059082.1 | Halomonas titanicae | 
| 28 | 2250872 | 2251090 | - | NC_020541.1 | Rhodanobacter denitrificans | 
| 29 | 2009853 | 2010071 | - | NC_020541.1 | Rhodanobacter denitrificans | 
| 30 | 2232719 | 2232937 | + | NC_020541.1 | Rhodanobacter denitrificans | 
| 31 | 5732523 | 5732759 | - | NZ_CP051487.1 | Pseudomonas umsongensis | 
| 32 | 5414429 | 5414665 | - | NZ_CP051487.1 | Pseudomonas umsongensis | 
| Neighborhood Conservation Analysis | 
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information | 
|---|---|---|---|---|---|---|
| 1 | PF02411.17 | 0.9 | 18 | 2837 | same-strand | MerT mercuric transport protein | 
| 2 | PF00403.28 | 1.0 | 20 | 2137 | same-strand | Heavy-metal-associated domain | 
| 3 | PF03203.16 | 0.8 | 16 | 2105 | same-strand | MerC mercury resistance protein | 
| 4 | PF07992.16 | 1.0 | 20 | 380.0 | same-strand | Pyridine nucleotide-disulphide oxidoreductase | 
| 5 | PF02852.24 | 1.0 | 20 | 380.0 | same-strand | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain | 
| 6 | PF00070.29 | 1.0 | 20 | 380.0 | same-strand | Pyridine nucleotide-disulphide oxidoreductase | 
| 7 | PF13411.8 | 1.0 | 20 | -3 | same-strand | MerR HTH family regulatory protein | 
| 8 | PF00239.23 | 0.6 | 12 | 903 | same-strand | Resolvase, N terminal domain | 
| 9 | PF11809.10 | 0.7 | 14 | 66 | same-strand | Domain of unknown function (DUF3330) |