Result : Q74DU7
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | DNA gyrase inhibitor YacG |
| NCBI Accession ID | AE017180.2 |
| Organism | Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) |
| Left | 1321807 |
| Right | 1321986 |
| Strand | + |
| Nucleotide Sequence | ATGATTACCACGCTGACATGCCCCCGCTGTCGAGCCGAAACCGTCTGGGAGGGGAATCCCCACCGGCCGTTCTGCTCGGCACGCTGCAAGACCGTTGATCTGGCCGCCTGGGCCGACGAGGAGTATCGCATCGCCGGTCCCGAAGCCCCTTCCGACAACGACGAAAACGACCGAGAGTAA |
| Sequence | MITTLTCPRCRAETVWEGNPHRPFCSARCKTVDLAAWADEEYRIAGPEAPSDNDENDRE |
| Source of smORF | Swiss-Prot |
| Function | Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. {ECO:0000255|HAMAP-Rule:MF_00649}. |
| Pubmed ID | 14671304 |
| Domain | CDD:412768 |
| Functional Category | Metal-binding |
| Uniprot ID | Q74DU7 |
| ORF Length (Amino Acid) | 59 |
++ More..
| Conservation Analysis |
No. of Species: 128
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 1321807 | 1321986 | + | NC_002939.5 | Geobacter sulfurreducens PCA |
| 2 | 1547242 | 1547412 | + | NZ_CP009788.1 | Geobacter pickeringii |
| 3 | 1951210 | 1951377 | + | NC_007517.1 | Geobacter metallireducens GS-15 |
| 4 | 2456095 | 2456283 | - | NZ_AP023213.1 | Citrifermentans bremense |
| 5 | 2651159 | 2651347 | - | NC_011146.1 | Citrifermentans bemidjiense Bem |
| 6 | 2750874 | 2751059 | + | NZ_CP044483.1 | Acinetobacter schindleri |
| 7 | 3642650 | 3642844 | + | NZ_CP065820.1 | Acinetobacter seifertii |
| 8 | 1515214 | 1515408 | + | NZ_CP070518.1 | Acinetobacter calcoaceticus |
| 9 | 3729016 | 3729210 | + | NC_014259.1 | Acinetobacter oleivorans DR1 |
| 10 | 2213707 | 2213874 | - | NZ_CP010311.1 | Geoalkalibacter subterraneus |
| 11 | 3539147 | 3539341 | - | NC_016603.1 | Acinetobacter pittii PHEA-2 |
| 12 | 349900 | 350085 | - | NZ_CP045650.1 | Acinetobacter wanghuae |
| 13 | 462165 | 462350 | + | NZ_CP012808.1 | Acinetobacter equi |
| 14 | 1583137 | 1583328 | + | NZ_LR134343.1 | Moraxella cuniculi |
| 15 | 1623087 | 1623281 | + | NZ_CP040105.1 | Acinetobacter nosocomialis M2 |
| 16 | 3528546 | 3528740 | + | NZ_CP015121.1 | Acinetobacter baumannii |
| 17 | 2874975 | 2875166 | + | NZ_CP024632.1 | Acinetobacter junii |
| 18 | 1192322 | 1192507 | + | NC_014147.1 | Moraxella catarrhalis BBH18 |
| 19 | 419892 | 420083 | - | NC_005966.1 | Acinetobacter baylyi ADP1 |
| 20 | 2289898 | 2290101 | - | NZ_CP008781.1 | Burkholderia pseudomallei |
| 21 | 705541 | 705744 | + | NZ_CP009727.1 | Burkholderia mallei |
| 22 | 1278570 | 1278773 | - | NC_007651.1 | Burkholderia thailandensis E264 |
| 23 | 293167 | 293346 | + | NZ_CP018787.1 | Oxalobacter formigenes |
| 24 | 1269055 | 1269237 | - | NZ_CP030241.1 | Moraxella bovis |
| 25 | 2233316 | 2233519 | - | NZ_CP009555.1 | Burkholderia oklahomensis C6786 |
| 26 | 3090081 | 3090254 | + | NZ_CP035934.2 | Acinetobacter cumulans |
| 27 | 909858 | 910031 | - | NZ_CP071766.1 | Acinetobacter towneri |
| 28 | 1518164 | 1518343 | + | NZ_CP065728.1 | Moraxella nonliquefaciens |
| 29 | 3111961 | 3112161 | + | NZ_CP034035.1 | Brenneria rubrifaciens |
| 30 | 469645 | 469857 | + | NZ_CP014234.1 | Moraxella osloensis |
| 31 | 3038227 | 3038418 | + | NZ_CP030880.1 | Acinetobacter haemolyticus |
| 32 | 191426 | 191620 | - | NZ_CP016414.1 | Vibrio scophthalmi |
| 33 | 252706 | 252900 | - | NZ_CP009977.1 | Vibrio natriegens NBRC 15636 = ATCC 14048 = DSM 759 |
| 34 | 4204166 | 4204333 | + | NZ_AP014630.1 | Acinetobacter guillouiae |
| 35 | 537722 | 537919 | - | NZ_CP039700.1 | Vibrio cyclitrophicus |
| 36 | 490608 | 490781 | - | NZ_CP029397.2 | Acinetobacter defluvii |
| 37 | 549130 | 549330 | - | NZ_CP045235.1 | Burkholderia cepacia |
| 38 | 399669 | 399863 | - | NZ_AP019651.1 | Vibrio taketomensis |
| 39 | 387309 | 387461 | - | NZ_CP071325.1 | Photobacterium ganghwense |
| 40 | 2856295 | 2856471 | - | NZ_CP025792.1 | Vibrio jasicida 090810c |
| 41 | 1829752 | 1829952 | - | NZ_CP011503.1 | Burkholderia pyrrocinia |
| 42 | 2434548 | 2434742 | - | NZ_CP019959.1 | Vibrio owensii |
| 43 | 548719 | 548919 | - | NZ_CP013401.1 | Burkholderia metallica |
| 44 | 472704 | 472850 | - | NZ_CP012621.1 | Zobellella denitrificans |
| 45 | 602370 | 602564 | - | NZ_CP031781.1 | Vibrio parahaemolyticus |
| 46 | 2745301 | 2745498 | + | NC_011753.2 | Vibrio atlanticus |
| 47 | 647063 | 647260 | - | NZ_CP009832.1 | Burkholderia multivorans ATCC BAA-247 |
| 48 | 704263 | 704463 | - | NZ_CP013414.1 | Burkholderia ubonensis |
| 49 | 2605656 | 2605817 | + | NZ_CP031093.1 | Hydrocarboniclastica marina |
| 50 | 5703299 | 5703478 | + | NZ_CP036401.1 | Massilia albidiflava |
| 51 | 2268744 | 2268938 | + | NZ_CP045300.1 | Kosakonia arachidis |
| 52 | 1619296 | 1619496 | - | NC_015682.1 | Thermodesulfobacterium geofontis OPF15 |
| 53 | 2501706 | 2501897 | + | NC_021287.1 | Caballeronia insecticola |
| 54 | 528783 | 528980 | - | NZ_CP065534.1 | Lonsdalea populi |
| 55 | 500968 | 501117 | + | NZ_CP023009.1 | Lonsdalea britannica |
| 56 | 724976 | 725125 | - | NZ_CP070624.1 | Photobacterium damselae subsp. damselae |
| 57 | 637131 | 637331 | - | NZ_CP013459.1 | Burkholderia stagnalis |
| 58 | 491838 | 491993 | - | NZ_CP017715.1 | Marinobacter salinus |
| 59 | 1028150 | 1028344 | - | NC_013456.1 | Vibrio antiquarius |
| 60 | 545155 | 545355 | - | NC_007510.1 | Burkholderia lata |
| 61 | 579917 | 580111 | - | NZ_CP032093.1 | Vibrio alfacsensis |
| 62 | 388989 | 389174 | - | NZ_CP011930.1 | Herbaspirillum seropedicae |
| 63 | 2646371 | 2646565 | + | NZ_CP030788.1 | Vibrio campbellii |
| 64 | 607860 | 608060 | - | NZ_CP020737.1 | Paraburkholderia acidophila |
| 65 | 558606 | 558806 | - | NZ_CP013398.1 | Burkholderia seminalis |
| 66 | 1813083 | 1813268 | - | NZ_CP024608.1 | Massilia violaceinigra |
| 67 | 3209982 | 3210176 | + | NZ_CP009467.1 | Vibrio harveyi |
| 68 | 393914 | 394108 | - | NZ_CP018312.1 | Vibrio rotiferianus |
| 69 | 419732 | 419923 | - | NZ_CP011568.3 | Pandoraea thiooxydans |
| 70 | 4078597 | 4078785 | + | NZ_CP013235.1 | Collimonas arenae |
| 71 | 2009874 | 2010071 | - | NZ_CP065150.1 | Vibrio kanaloae |
| 72 | 1783864 | 1784010 | + | NZ_CP021376.1 | Oceanisphaera avium |
| 73 | 1558116 | 1558304 | - | NZ_CP020931.1 | Marinobacter salarius |
| 74 | 3108925 | 3109116 | - | NZ_CP034464.1 | Undibacterium parvum |
| 75 | 987503 | 987688 | - | NZ_CP041352.1 | Casimicrobium huifangae |
| 76 | 2626790 | 2626939 | + | NZ_CP047475.1 | Vibrio astriarenae |
| 77 | 706841 | 707026 | - | NC_012912.1 | Dickeya chrysanthemi Ech1591 |
| 78 | 4106326 | 4106511 | + | NC_014500.1 | Dickeya dadantii 3937 |
| 79 | 325768 | 325944 | + | NZ_CP059567.1 | Neisseria shayeganii |
| 80 | 336532 | 336705 | - | NC_014394.1 | Gallionella capsiferriformans ES-2 |
| 81 | 2289124 | 2289306 | + | NZ_CP059569.1 | Kingella oralis |
| 82 | 3625490 | 3625675 | - | NZ_CP009460.1 | Dickeya fangzhongdai |
| 83 | 1150213 | 1150404 | + | NZ_CP021377.1 | Oceanisphaera profunda |
| 84 | 3939134 | 3939319 | + | NZ_CP025799.1 | Dickeya zeae |
| 85 | 4852004 | 4852159 | + | NZ_CP024159.1 | Pseudomonas mosselii |
| 86 | 3852475 | 3852681 | + | NZ_CP046293.1 | Yersinia intermedia |
| 87 | 3215008 | 3215214 | + | NC_010995.1 | Cellvibrio japonicus Ueda107 |
| 88 | 2552319 | 2552474 | + | NC_017506.1 | Marinobacter adhaerens HP15 |
| 89 | 4971474 | 4971629 | + | NC_008027.1 | Pseudomonas entomophila L48 |
| 90 | 4027392 | 4027580 | + | NZ_CP009365.1 | Pseudomonas soli |
| 91 | 614291 | 614476 | + | NZ_CP031700.1 | Neisseria zalophi |
| 92 | 812034 | 812234 | - | NZ_CP012264.1 | Cronobacter condimenti 1330 |
| 93 | 716523 | 716714 | + | NZ_LR134510.1 | Actinobacillus delphinicola |
| 94 | 1015894 | 1016091 | - | NZ_LR134531.1 | Pragia fontium |
| 95 | 3110113 | 3110307 | + | NZ_CP026111.1 | Paraburkholderia terrae |
| 96 | 1092525 | 1092680 | - | NZ_CP054205.1 | Pseudomonas rhodesiae |
| 97 | 3107564 | 3107740 | + | NC_015677.1 | Ramlibacter tataouinensis TTB310 |
| 98 | 675255 | 675410 | - | NZ_CP012400.2 | Pseudomonas yamanorum |
| 99 | 989144 | 989332 | - | NZ_CP038033.1 | Nitrosococcus wardiae |
| 100 | 529635 | 529799 | - | NC_012969.1 | Methylovorus glucosetrophus SIP3-4 |
| 101 | 439009 | 439161 | - | NZ_CP040021.1 | Salinivibrio kushneri |
| 102 | 2123806 | 2124006 | + | NZ_AP018689.1 | Vibrio aphrogenes |
| 103 | 5242655 | 5242810 | + | NC_021505.1 | Pseudomonas putida NBRC 14164 |
| 104 | 551982 | 552185 | + | NZ_CP051461.1 | Polaromonas vacuolata |
| 105 | 4193028 | 4193183 | - | NZ_CP031146.1 | Pseudomonas plecoglossicida |
| 106 | 5395978 | 5396157 | + | NZ_CP024645.1 | Rhizobacter gummiphilus |
| 107 | 2796990 | 2797139 | + | NZ_CP067057.1 | Rahnella aceris |
| 108 | 4911881 | 4912036 | + | NZ_CP071706.1 | Pseudomonas donghuensis |
| 109 | 671005 | 671205 | - | NC_008260.1 | Alcanivorax borkumensis SK2 |
| 110 | 917897 | 918052 | - | NZ_CP043311.1 | Pseudomonas lalkuanensis |
| 111 | 804111 | 804266 | - | NZ_CP022562.1 | Pseudomonas monteilii |
| 112 | 949977 | 950132 | - | NZ_CP018420.1 | Pseudomonas veronii |
| 113 | 892868 | 893023 | - | NZ_CP023272.1 | Pseudomonas lurida |
| 114 | 871372 | 871527 | - | NZ_CP027723.1 | Pseudomonas orientalis |
| 115 | 874280 | 874435 | - | NZ_CP010896.1 | Pseudomonas simiae |
| 116 | 5923602 | 5923802 | + | NZ_CP051487.1 | Pseudomonas umsongensis |
| 117 | 1052892 | 1053092 | - | NZ_CP070503.1 | Pseudomonas atacamensis |
| 118 | 1014529 | 1014684 | - | NZ_CP027756.1 | Pseudomonas synxantha |
| 119 | 4417794 | 4417952 | - | NZ_CP009533.1 | Pseudomonas rhizosphaerae |
| 120 | 5710041 | 5710247 | + | NZ_CP035088.1 | Pseudomonas viciae |
| 121 | 1845888 | 1846052 | + | NZ_CP041730.1 | Chitinimonas arctica |
| 122 | 5880744 | 5880902 | + | NZ_LS999205.1 | Pseudomonas protegens CHA0 |
| 123 | 5737471 | 5737626 | + | NZ_CP014205.2 | Pseudomonas glycinae |
| 124 | 5581717 | 5581872 | + | NZ_CP062253.1 | Pseudomonas gozinkensis |
| 125 | 5382849 | 5383004 | + | NZ_CP029608.1 | Pseudomonas kribbensis |
| 126 | 5603711 | 5603866 | + | NZ_CP062252.1 | Pseudomonas allokribbensis |
| 127 | 950356 | 950550 | - | NZ_CP046621.1 | Pseudomonas alkylphenolica |
| 128 | 1038883 | 1039065 | - | NZ_CP004387.1 | Alcanivorax pacificus W11-5 |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NZ_CP008781.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF01121.22 | 0.73 | 94 | 822.5 | same-strand | Dephospho-CoA kinase |
| 2 | PF06750.15 | 0.65 | 83 | 1447 | same-strand | Bacterial Peptidase A24 N-terminal domain |
| 3 | PF01478.20 | 0.66 | 84 | 1449.5 | same-strand | Type IV leader peptidase family |
| 4 | PF00482.25 | 0.7 | 90 | 2397.5 | same-strand | Type II secretion system (T2SS), protein F |
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