Result : Q55842
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Phosphoribosylformylglycinamidine synthase subunit PurS (FGAM synthase) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase subunit III) (FGAR amidotransferase III) (FGAR-AT III) (Phosphoribosylformylglycinamidine synthase subunit III) |
| NCBI Accession ID | BA000022.2 |
| Organism | Synechocystis sp. (strain PCC 6803 / Kazusa) |
| Left | 2932211 |
| Right | 2932513 |
| Strand | + |
| Nucleotide Sequence | GTGGCAGATTCCCCGGTAAGGCCCTCCATGTCCCATTCCTACCATTGTCGTATTTACGTTACCCTACGTCCCTCCGTGCTTGACCCCGCTGGGACTGCTGTGCAATCTGGTTTGCAACAATTGGGCTACGATGGCGTTTCCCAGGTCAGAATTGGTAAATACATTGAGTTAACCCTCGAGGCCCCGGACGAAGCCACCGCTTCCCAACAGCTAGACACCATGTGTGACCAACTATTGGCCAATACGGTGATCGAAAATTATTGCTTTGAAATTACCGCCCTAGAAGGTGCCGTCACACCATGA |
| Sequence | MADSPVRPSMSHSYHCRIYVTLRPSVLDPAGTAVQSGLQQLGYDGVSQVRIGKYIELTLEAPDEATASQQLDTMCDQLLANTVIENYCFEITALEGAVTP |
| Source of smORF | Swiss-Prot |
| Function | Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. {ECO:0000255|HAMAP-Rule:MF_01926}. |
| Pubmed ID | 8590279 8905231 |
| Domain | CDD:412569 |
| Functional Category | Others |
| Uniprot ID | Q55842 |
| ORF Length (Amino Acid) | 100 |
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| Conservation Analysis |
No. of Species: 51
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 2502832 | 2503077 | + | NC_011729.1 | Gloeothece citriformis PCC 7424 |
| 2 | 5632979 | 5633257 | + | NC_014501.1 | Gloeothece verrucosa PCC 7822 |
| 3 | 2334691 | 2334957 | - | NC_019748.1 | Stanieria cyanosphaera PCC 7437 |
| 4 | 2662111 | 2662374 | - | NC_019776.1 | Cyanobacterium aponinum PCC 10605 |
| 5 | 3297343 | 3297621 | + | NC_019689.1 | Pleurocapsa sp. PCC 7327 |
| 6 | 283947 | 284189 | - | NC_022600.1 | Gloeobacter kilaueensis JS1 |
| 7 | 1426851 | 1427129 | - | NC_009925.1 | Acaryochloris marina MBIC11017 |
| 8 | 5298509 | 5298784 | + | NC_010296.1 | Microcystis aeruginosa NIES-843 |
| 9 | 2260765 | 2261043 | + | NZ_CP060822.1 | Cylindrospermopsis curvispora GIHE-G1 |
| 10 | 2157384 | 2157662 | + | NC_019753.1 | Crinalium epipsammum PCC 9333 |
| 11 | 8141337 | 8141585 | + | NC_010628.1 | Nostoc punctiforme PCC 73102 |
| 12 | 1652964 | 1653212 | - | NZ_CP054698.1 | Nostoc edaphicum CCNP1411 |
| 13 | 1814296 | 1814544 | + | NZ_CP047242.1 | Trichormus variabilis 0441 |
| 14 | 4303718 | 4304002 | - | NC_019729.1 | Oscillatoria nigro-viridis PCC 7112 |
| 15 | 456275 | 456523 | + | NZ_CP024785.1 | Nostoc flagelliforme CCNUN1 |
| 16 | 469031 | 469309 | + | NC_019780.1 | Dactylococcopsis salina PCC 8305 |
| 17 | 1455495 | 1455761 | + | NZ_AP014638.1 | Leptolyngbya boryana IAM M-101 |
| 18 | 470524 | 470790 | - | NC_005125.1 | Gloeobacter violaceus PCC 7421 |
| 19 | 1927976 | 1928224 | - | NZ_CP031941.1 | Nostoc sphaeroides |
| 20 | 3428260 | 3428523 | - | NZ_CP021983.2 | Halomicronema hongdechloris C2206 |
| 21 | 3576073 | 3576351 | - | NC_014248.1 | 'Nostoc azollae' 0708 |
| 22 | 173053 | 173331 | - | NC_019751.1 | Calothrix sp. PCC 6303 |
| 23 | 4442741 | 4443019 | + | NC_019771.1 | Anabaena cylindrica PCC 7122 |
| 24 | 2030202 | 2030480 | + | NZ_CP042326.1 | Euhalothece natronophila Z-M001 |
| 25 | 5937049 | 5937333 | + | NC_019693.1 | Oscillatoria acuminata PCC 6304 |
| 26 | 2138064 | 2138306 | + | NZ_AP018202.1 | Thermostichus vulcanus NIES-2134 |
| 27 | 2270067 | 2270309 | + | NC_004113.1 | Thermosynechococcus vestitus BP-1 |
| 28 | 839391 | 839639 | + | NZ_CP034235.1 | Paenibacillus psychroresistens |
| 29 | 5231809 | 5232057 | - | NZ_CP026363.1 | Brevibacillus agri |
| 30 | 2593273 | 2593530 | + | NZ_CP017705.1 | Brevibacillus laterosporus DSM 25 |
| 31 | 873591 | 873845 | + | NC_018870.1 | Thermacetogenium phaeum DSM 12270 |
| 32 | 4213291 | 4213539 | - | NZ_CP022657.1 | Tumebacillus algifaecis |
| 33 | 248265 | 248519 | + | NZ_CP024955.1 | Kyrpidia spormannii |
| 34 | 5609425 | 5609673 | - | NZ_LR134338.1 | Brevibacillus brevis |
| 35 | 806167 | 806421 | + | NC_014098.1 | Kyrpidia tusciae DSM 2912 |
| 36 | 8180089 | 8180334 | - | NC_017672.3 | Paenibacillus mucilaginosus K02 |
| 37 | 2434563 | 2434823 | - | NC_014378.1 | Acetohalobium arabaticum DSM 5501 |
| 38 | 605536 | 605781 | + | NC_017668.1 | Halobacillus halophilus DSM 2266 |
| 39 | 4459121 | 4459363 | + | NC_019973.1 | Mesorhizobium australicum WSM2073 |
| 40 | 3572235 | 3572480 | - | NZ_CP020772.1 | Halobacillus mangrovi |
| 41 | 3297688 | 3297957 | + | NZ_CP004388.1 | Thalassospira xiamenensis M-5 = DSM 17429 |
| 42 | 49247 | 49489 | - | NC_002678.2 | Mesorhizobium japonicum MAFF 303099 |
| 43 | 3908036 | 3908290 | - | NZ_CP065425.1 | Heyndrickxia vini |
| 44 | 4906845 | 4907087 | + | NC_015675.1 | Mesorhizobium opportunistum WSM2075 |
| 45 | 1460086 | 1460328 | + | NZ_CP053856.1 | Rhizobium pusense |
| 46 | 1891571 | 1891813 | + | NZ_LT605585.1 | Brucella inopinata |
| 47 | 1003311 | 1003565 | + | NZ_CP009416.1 | Jeotgalibacillus malaysiensis |
| 48 | 3002423 | 3002668 | - | NZ_CP012024.1 | Bacillus smithii |
| 49 | 805626 | 805868 | - | NZ_CP060780.1 | Sphingomonas daechungensis |
| 50 | 2730680 | 2730922 | - | NZ_CP060782.1 | Sphingomonas sediminicola |
| 51 | 2468178 | 2468438 | + | NZ_CP004372.1 | Roseibacterium elongatum DSM 19469 |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NC_011729.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF13507.8 | 0.96 | 49 | 20 | same-strand | CobB/CobQ-like glutamine amidotransferase domain |
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