Result : Q49946
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Putative ESAT-6-like protein X |
| NCBI Accession ID | U15180.1 |
| Organism | Mycobacterium leprae (strain TN) |
| Left | 2055 |
| Right | 2342 |
| Strand | + |
| Nucleotide Sequence | ATGGGAAACATTAACTACCAGTTTGGGGAGATCGACGCACATGGAGCGGCTATCCGCGCTCAAGCGGCTGCGTTGGAGACCACCCACCAGGCCATTCTAGCCACTGTGCGGGACGCCGCTGAGTTTTGGGGCGGACAAGGTTCGACTGCCCATGAAATGTTCATAGCCGACCTGGGTCGTAACTTCCAGATGATTTACGAGCAGGCCAACTCTCACGGCCAAAAGGTGCAACGCGCCAGCTCCTCCATGGCTGACACTGACCGCTCTGTCAGTTCCGCTTGGTCCTAA |
| Sequence | MGNINYQFGEIDAHGAAIRAQAAALETTHQAILATVRDAAEFWGGQGSTAHEMFIADLGRNFQMIYEQANSHGQKVQRASSSMADTDRSVSSAWS |
| Source of smORF | Swiss-Prot |
| Function | The ORF matches to the profile of cl02005. Profile Description: Proteins of 100 residues with WXG. T7SS_ESX-EspC is a family of exported virulence proteins from largely Acinetobacteria and a few Fimicutes, Gram-positive bacteria. It is exported in conjunction with EspA as an interacting pair.ED F8ADQ6.1/227-313; F8ADQ6.1/227-313; |
| Pubmed ID | 11234002 |
| Domain | CDD:413154 |
| Functional Category | Others |
| Uniprot ID | Q49946 |
| ORF Length (Amino Acid) | 95 |
++ More..
| Conservation Analysis |
No. of Species: 35
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 946614 | 946901 | + | NZ_CP011883.2 | Mycobacterium haemophilum DSM 44634 |
| 2 | 3134697 | 3134984 | - | NZ_CP011883.2 | Mycobacterium haemophilum DSM 44634 |
| 3 | 2949994 | 2950281 | + | NZ_CP011883.2 | Mycobacterium haemophilum DSM 44634 |
| 4 | 3352525 | 3352812 | - | NZ_CP011883.2 | Mycobacterium haemophilum DSM 44634 |
| 5 | 1803123 | 1803410 | - | NZ_CP011883.2 | Mycobacterium haemophilum DSM 44634 |
| 6 | 3357433 | 3357720 | - | NZ_CP011883.2 | Mycobacterium haemophilum DSM 44634 |
| 7 | 1326499 | 1326786 | - | NZ_CP011883.2 | Mycobacterium haemophilum DSM 44634 |
| 8 | 2958593 | 2958880 | + | NZ_CP011883.2 | Mycobacterium haemophilum DSM 44634 |
| 9 | 3300101 | 3300385 | + | NZ_CP011883.2 | Mycobacterium haemophilum DSM 44634 |
| 10 | 2760124 | 2760363 | - | NZ_CP011883.2 | Mycobacterium haemophilum DSM 44634 |
| 11 | 2661392 | 2661676 | - | NZ_AP024310.1 | Mycobacterium heckeshornense |
| 12 | 2646376 | 2646660 | - | NZ_AP024310.1 | Mycobacterium heckeshornense |
| 13 | 1312092 | 1312376 | - | NZ_AP024310.1 | Mycobacterium heckeshornense |
| 14 | 3519674 | 3519931 | - | NZ_AP022583.1 | Mycobacterium noviomagense |
| 15 | 4211883 | 4212167 | + | NZ_AP022583.1 | Mycobacterium noviomagense |
| 16 | 749678 | 749962 | + | NZ_AP022583.1 | Mycobacterium noviomagense |
| 17 | 4229014 | 4229298 | + | NZ_AP022583.1 | Mycobacterium noviomagense |
| 18 | 4244653 | 4244937 | + | NZ_AP022583.1 | Mycobacterium noviomagense |
| 19 | 3471718 | 3472002 | - | NZ_AP022583.1 | Mycobacterium noviomagense |
| 20 | 3473503 | 3473742 | - | NZ_AP022583.1 | Mycobacterium noviomagense |
| 21 | 2607072 | 2607356 | - | NZ_AP022606.1 | Mycobacterium branderi |
| 22 | 2754980 | 2755264 | + | NZ_AP022606.1 | Mycobacterium branderi |
| 23 | 2540633 | 2540917 | - | NZ_AP022606.1 | Mycobacterium branderi |
| 24 | 4131405 | 4131644 | - | NZ_AP022606.1 | Mycobacterium branderi |
| 25 | 2608318 | 2608602 | - | NZ_AP022606.1 | Mycobacterium branderi |
| 26 | 4118721 | 4118960 | - | NZ_AP022606.1 | Mycobacterium branderi |
| 27 | 509312 | 509596 | - | NZ_AP022607.1 | Mycobacterium branderi |
| 28 | 491771 | 492055 | - | NZ_AP022607.1 | Mycobacterium branderi |
| 29 | 9737 | 9994 | + | NZ_AP022575.1 | Mycobacterium shinjukuense |
| 30 | 4496085 | 4496342 | + | NZ_AP022575.1 | Mycobacterium shinjukuense |
| 31 | 996091 | 996348 | + | NZ_AP022575.1 | Mycobacterium shinjukuense |
| 32 | 1547833 | 1548090 | - | NZ_AP022575.1 | Mycobacterium shinjukuense |
| 33 | 4164553 | 4164810 | + | NZ_AP022575.1 | Mycobacterium shinjukuense |
| 34 | 268743 | 269000 | - | NZ_AP022575.1 | Mycobacterium shinjukuense |
| 35 | 986961 | 987218 | + | NZ_AP022575.1 | Mycobacterium shinjukuense |
| 36 | 1238649 | 1238888 | + | NZ_AP022590.1 | Mycobacterium mantenii |
| 37 | 5773825 | 5774064 | - | NZ_AP022590.1 | Mycobacterium mantenii |
| 38 | 5018537 | 5018821 | + | NZ_AP018410.1 | Mycobacterium pseudoshottsii JCM 15466 |
| 39 | 384237 | 384521 | + | NZ_AP018410.1 | Mycobacterium pseudoshottsii JCM 15466 |
| 40 | 4035784 | 4036068 | - | NZ_AP018410.1 | Mycobacterium pseudoshottsii JCM 15466 |
| 41 | 2987045 | 2987329 | + | NZ_AP018410.1 | Mycobacterium pseudoshottsii JCM 15466 |
| 42 | 3960136 | 3960420 | + | NZ_AP018410.1 | Mycobacterium pseudoshottsii JCM 15466 |
| 43 | 1062918 | 1063202 | - | NC_016946.1 | Mycobacterium intracellulare ATCC 13950 |
| 44 | 2868829 | 2869113 | - | NC_016946.1 | Mycobacterium intracellulare ATCC 13950 |
| 45 | 3910058 | 3910342 | + | NZ_AP022572.1 | Mycobacterium shottsii |
| 46 | 226963 | 227247 | + | NZ_AP022572.1 | Mycobacterium shottsii |
| 47 | 579515 | 579799 | - | NZ_AP022572.1 | Mycobacterium shottsii |
| 48 | 3193618 | 3193902 | + | NZ_AP022572.1 | Mycobacterium shottsii |
| 49 | 3187180 | 3187437 | + | NZ_AP022572.1 | Mycobacterium shottsii |
| 50 | 2748616 | 2748900 | - | NC_016948.1 | Mycobacterium paraintracellulare |
| 51 | 1076567 | 1076851 | - | NC_016948.1 | Mycobacterium paraintracellulare |
| 52 | 3242725 | 3243009 | - | NZ_AP022573.1 | Mycobacterium saskatchewanense |
| 53 | 2484187 | 2484444 | + | NZ_AP022573.1 | Mycobacterium saskatchewanense |
| 54 | 1597041 | 1597298 | - | NZ_AP022573.1 | Mycobacterium saskatchewanense |
| 55 | 1598300 | 1598584 | - | NZ_AP022573.1 | Mycobacterium saskatchewanense |
| 56 | 721474 | 721758 | + | NZ_AP022573.1 | Mycobacterium saskatchewanense |
| 57 | 3320844 | 3321101 | + | NZ_AP022581.1 | Mycobacterium lacus |
| 58 | 2565408 | 2565692 | - | NZ_AP022581.1 | Mycobacterium lacus |
| 59 | 2573573 | 2573830 | - | NZ_AP022581.1 | Mycobacterium lacus |
| 60 | 1857436 | 1857693 | + | NZ_AP022581.1 | Mycobacterium lacus |
| 61 | 679602 | 679859 | + | NZ_AP022581.1 | Mycobacterium lacus |
| 62 | 2534707 | 2534991 | - | NZ_CP009360.4 | Mycobacterium avium subsp. hominissuis |
| 63 | 1059952 | 1060236 | - | NZ_CP009360.4 | Mycobacterium avium subsp. hominissuis |
| 64 | 2724787 | 2725071 | + | NZ_CP009360.4 | Mycobacterium avium subsp. hominissuis |
| 65 | 2653709 | 2653993 | - | NZ_CP023147.1 | Mycobacterium marseillense |
| 66 | 1045524 | 1045808 | - | NZ_CP023147.1 | Mycobacterium marseillense |
| 67 | 3894229 | 3894513 | - | NZ_AP022568.1 | Mycobacterium simiae |
| 68 | 5568744 | 5569028 | - | NZ_AP022568.1 | Mycobacterium simiae |
| 69 | 5313977 | 5314261 | - | NZ_AP022568.1 | Mycobacterium simiae |
| 70 | 2001230 | 2001469 | + | NZ_LT906469.1 | Mycolicibacter terrae |
| 71 | 2481832 | 2482071 | - | NZ_LT906469.1 | Mycolicibacter terrae |
| 72 | 2460317 | 2460556 | + | NZ_LT906469.1 | Mycolicibacter terrae |
| 73 | 1992355 | 1992594 | + | NZ_LT906469.1 | Mycolicibacter terrae |
| 74 | 1512184 | 1512423 | + | NZ_AP022582.1 | Mycobacterium seoulense |
| 75 | 3004730 | 3004969 | + | NZ_AP022582.1 | Mycobacterium seoulense |
| 76 | 3768666 | 3768950 | - | NZ_AP022582.1 | Mycobacterium seoulense |
| 77 | 789320 | 789559 | + | NZ_AP022619.1 | Mycobacterium paraseoulense |
| 78 | 2932705 | 2932944 | + | NZ_AP022619.1 | Mycobacterium paraseoulense |
| 79 | 3606409 | 3606693 | - | NZ_AP022619.1 | Mycobacterium paraseoulense |
| 80 | 49397 | 49681 | + | NC_022663.1 | Mycobacterium kansasii ATCC 12478 |
| 81 | 1875009 | 1875293 | + | NC_022663.1 | Mycobacterium kansasii ATCC 12478 |
| 82 | 1055621 | 1055905 | - | NC_022663.1 | Mycobacterium kansasii ATCC 12478 |
| 83 | 2755083 | 2755367 | - | NC_022663.1 | Mycobacterium kansasii ATCC 12478 |
| 84 | 1012449 | 1012733 | - | NZ_CP058277.1 | Mycobacterium marinum |
| 85 | 5769232 | 5769516 | - | NZ_CP058277.1 | Mycobacterium marinum |
| 86 | 4636171 | 4636455 | + | NZ_CP058277.1 | Mycobacterium marinum |
| 87 | 285123 | 285407 | + | NZ_CP058277.1 | Mycobacterium marinum |
| 88 | 5692449 | 5692733 | + | NZ_CP058277.1 | Mycobacterium marinum |
| 89 | 5777811 | 5778068 | - | NZ_CP058277.1 | Mycobacterium marinum |
| 90 | 5775695 | 5775952 | - | NZ_CP058277.1 | Mycobacterium marinum |
| 91 | 502343 | 502582 | + | NZ_AP022609.1 | Mycolicibacter hiberniae |
| 92 | 2096178 | 2096417 | + | NZ_AP022609.1 | Mycolicibacter hiberniae |
| 93 | 1927665 | 1927904 | - | NZ_AP022609.1 | Mycolicibacter hiberniae |
| 94 | 1474005 | 1474244 | + | NZ_AP022609.1 | Mycolicibacter hiberniae |
| 95 | 1482790 | 1483029 | + | NZ_AP022609.1 | Mycolicibacter hiberniae |
| 96 | 570661 | 570945 | - | NZ_AP022609.1 | Mycolicibacter hiberniae |
| 97 | 4471320 | 4471604 | + | NZ_LR130759.1 | Mycobacterium basiliense |
| 98 | 3708076 | 3708360 | - | NZ_LR130759.1 | Mycobacterium basiliense |
| 99 | 2793786 | 2794070 | + | NZ_LR130759.1 | Mycobacterium basiliense |
| 100 | 3720053 | 3720292 | - | NZ_LR130759.1 | Mycobacterium basiliense |
| 101 | 370559 | 370843 | + | NZ_AP022569.1 | Mycobacterium cookii |
| 102 | 1991099 | 1991383 | + | NZ_AP022569.1 | Mycobacterium cookii |
| 103 | 2252725 | 2253009 | + | NZ_AP022569.1 | Mycobacterium cookii |
| 104 | 2324096 | 2324380 | + | NZ_AP022569.1 | Mycobacterium cookii |
| 105 | 906865 | 907104 | + | NZ_AP022569.1 | Mycobacterium cookii |
| 106 | 3898782 | 3899021 | + | NZ_AP022615.1 | Mycobacterium heidelbergense |
| 107 | 4575271 | 4575510 | - | NZ_AP022615.1 | Mycobacterium heidelbergense |
| 108 | 3204237 | 3204476 | - | NZ_AP022615.1 | Mycobacterium heidelbergense |
| 109 | 3900077 | 3900316 | + | NZ_AP022615.1 | Mycobacterium heidelbergense |
| 110 | 3821076 | 3821315 | + | NZ_AP022589.1 | Mycolicibacter minnesotensis |
| 111 | 3829879 | 3830118 | + | NZ_AP022589.1 | Mycolicibacter minnesotensis |
| 112 | 44929 | 45168 | - | NZ_AP022589.1 | Mycolicibacter minnesotensis |
| 113 | 224174 | 224413 | + | NZ_AP022589.1 | Mycolicibacter minnesotensis |
| 114 | 3760464 | 3760748 | - | NZ_AP022613.1 | Mycobacterium conspicuum |
| 115 | 2831338 | 2831622 | + | NZ_AP022613.1 | Mycobacterium conspicuum |
| 116 | 4652550 | 4652834 | + | NZ_AP022613.1 | Mycobacterium conspicuum |
| 117 | 1861157 | 1861441 | + | NZ_AP022613.1 | Mycobacterium conspicuum |
| 118 | 4522660 | 4522899 | - | NZ_CP025546.1 | Mycobacterium paragordonae |
| 119 | 4519312 | 4519551 | - | NZ_CP025546.1 | Mycobacterium paragordonae |
| 120 | 3398087 | 3398371 | + | NZ_CP025546.1 | Mycobacterium paragordonae |
| 121 | 5493034 | 5493318 | + | NZ_CP025546.1 | Mycobacterium paragordonae |
| 122 | 5134150 | 5134389 | - | NZ_AP022587.1 | Mycobacterium stomatepiae |
| 123 | 511238 | 511477 | + | NZ_AP022587.1 | Mycobacterium stomatepiae |
| 124 | 781951 | 782190 | - | NZ_AP022587.1 | Mycobacterium stomatepiae |
| 125 | 5881739 | 5881978 | + | NZ_AP022587.1 | Mycobacterium stomatepiae |
| 126 | 2730802 | 2731086 | + | NZ_AP018164.1 | Mycobacterium shigaense |
| 127 | 4249103 | 4249387 | + | NZ_AP018164.1 | Mycobacterium shigaense |
| 128 | 4883171 | 4883410 | - | NZ_AP022576.1 | Mycobacterium florentinum |
| 129 | 676588 | 676827 | - | NZ_AP022576.1 | Mycobacterium florentinum |
| 130 | 5644561 | 5644800 | + | NZ_AP022576.1 | Mycobacterium florentinum |
| 131 | 4059984 | 4060223 | - | NC_000962.3 | Mycobacterium tuberculosis H37Rv |
| 132 | 1160544 | 1160783 | - | NC_000962.3 | Mycobacterium tuberculosis H37Rv |
| 133 | 2030739 | 2030978 | + | NC_000962.3 | Mycobacterium tuberculosis H37Rv |
| 134 | 1341051 | 1341290 | + | NC_000962.3 | Mycobacterium tuberculosis H37Rv |
| 135 | 2625888 | 2626127 | - | NC_000962.3 | Mycobacterium tuberculosis H37Rv |
| 136 | 2073698 | 2073937 | + | NC_015848.1 | Mycobacterium canettii CIPT 140010059 |
| 137 | 2682991 | 2683230 | - | NC_015848.1 | Mycobacterium canettii CIPT 140010059 |
| 138 | 1171359 | 1171598 | - | NC_015848.1 | Mycobacterium canettii CIPT 140010059 |
| 139 | 1361107 | 1361346 | + | NC_015848.1 | Mycobacterium canettii CIPT 140010059 |
| 140 | 2691404 | 2691643 | - | NC_015848.1 | Mycobacterium canettii CIPT 140010059 |
| 141 | 4115384 | 4115623 | - | NC_015848.1 | Mycobacterium canettii CIPT 140010059 |
| 142 | 66052 | 66336 | - | NC_022654.1 | Mycobacterium kansasii ATCC 12478 |
| 143 | 5917610 | 5917867 | - | NZ_AP022614.1 | Mycobacterium parmense |
| 144 | 1553272 | 1553529 | - | NZ_AP022614.1 | Mycobacterium parmense |
| 145 | 658807 | 659064 | + | NZ_AP022614.1 | Mycobacterium parmense |
| 146 | 4392987 | 4393226 | - | NZ_AP022562.1 | Mycobacterium novum |
| 147 | 911854 | 912093 | + | NZ_AP022562.1 | Mycobacterium novum |
| 148 | 4384151 | 4384390 | - | NZ_AP022562.1 | Mycobacterium novum |
| 149 | 3884629 | 3884868 | + | NZ_AP022562.1 | Mycobacterium novum |
| 150 | 1073897 | 1074136 | - | NC_015576.1 | Mycolicibacter sinensis |
| 151 | 2065374 | 2065613 | + | NC_015576.1 | Mycolicibacter sinensis |
| 152 | 2074209 | 2074448 | + | NC_015576.1 | Mycolicibacter sinensis |
| 153 | 2563323 | 2563562 | - | NC_015576.1 | Mycolicibacter sinensis |
| 154 | 53185 | 53475 | + | NZ_CP025547.1 | Mycobacterium paragordonae |
++ More..
| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NZ_CP011883.2
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF00934.22 | 1.0 | 35 | 1667 | same-strand | PE family |
| 2 | PF00823.21 | 1.0 | 35 | 1008 | same-strand | PPE family |
| 3 | PF06013.14 | 1.0 | 35 | 66 | same-strand | Proteins of 100 residues with WXG |
| 4 | PF12484.10 | 1.0 | 35 | 1308 | same-strand | PPE-SVP subfamily C-terminal region |
| 5 | PF00072.26 | 0.89 | 31 | 499 | same-strand | Response regulator receiver domain |
| 6 | PF00486.30 | 0.89 | 31 | 499 | same-strand | Transcriptional regulatory protein, C terminal |
| 7 | PF00512.27 | 0.94 | 33 | 2172 | same-strand | His Kinase A (phospho-acceptor) domain |
| 8 | PF02518.28 | 0.94 | 33 | 2172 | same-strand | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
| 9 | PF00672.27 | 0.86 | 30 | 2585 | same-strand | HAMP domain |
| 10 | PF00004.31 | 0.83 | 29 | 5722 | same-strand | ATPase family associated with various cellular activities (AAA) |
| 11 | PF11203.10 | 0.97 | 34 | 4527 | same-strand | Putative type VII ESX secretion system translocon, EccE |
| 12 | PF08817.12 | 0.97 | 34 | 1263 | same-strand | WXG100 protein secretion system (Wss), protein YukD |
| 13 | PF14011.8 | 0.97 | 34 | 91 | same-strand | EspG family |
| 14 | PF19053.2 | 0.86 | 30 | 1263.0 | same-strand | EccD-like transmembrane domain |
++ More..