Result : P77527
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Protein DafA (DnaK-DnaJ assembly factor A) |
| NCBI Accession ID | Y07826.2 |
| Organism | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) |
| Left | 3588 |
| Right | 3824 |
| Strand | + |
| Nucleotide Sequence | ATGCTCGCGCGTAGCGGTTGGCTTTCCCTCGAGGCCCTCTCCGAGTACGGCCTTTCCCTGGCGGCCGTGCGGGCCTACGTGGAGATCGGCTTCGTGGAGCCTTTGGAGGTGGGCGGGGCCTGGTACTTCCGGGAGGAGGACCTCCTGAGGATGGCCAAGGCCGAACGCATCCGCAAGGACCTCGGGGCCAACCTCATCGGGGCGGCCCTGGTGGTGGAGATCCTGGAGCGCACTTAG |
| Sequence | MLARSGWLSLEALSEYGLSLAAVRAYVEIGFVEPLEVGGAWYFREEDLLRMAKAERIRKDLGANLIGAALVVEILERT |
| Source of smORF | Swiss-Prot |
| Function | Required for correct assembly of the DnaK-DnaJ complex in the resting state. Seems to stabilize this ternary complex until it is replaced by substrate proteins under heat-shock conditions. |
| Pubmed ID | 8663379 10092456 |
| Domain | CDD:413393 |
| Functional Category | Others |
| Uniprot ID | P77527 |
| ORF Length (Amino Acid) | 78 |
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| Conservation Analysis |
No. of Species: 9
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 1415492 | 1415728 | - | NC_006461.1 | Thermus thermophilus HB8 |
| 2 | 1744690 | 1744929 | - | NZ_CP010822.1 | Thermus aquaticus Y51MC23 |
| 3 | 576900 | 577136 | + | NZ_CP014141.1 | Thermus parvatiensis |
| 4 | 1367735 | 1367971 | + | NZ_CP038452.1 | Thermus caldilimi |
| 5 | 520329 | 520565 | + | NZ_CP016312.1 | Thermus brockianus |
| 6 | 630283 | 630519 | + | NC_019386.1 | Thermus oshimai JL-2 |
| 7 | 433327 | 433569 | - | NC_014212.1 | Meiothermus silvanus DSM 9946 |
| 8 | 416719 | 416961 | + | NC_015387.1 | Marinithermus hydrothermalis DSM 14884 |
| 9 | 1913145 | 1913381 | - | NC_014761.1 | Oceanithermus profundus DSM 14977 |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NC_006461.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF00004.31 | 1.0 | 9 | 3382 | opposite-strand | ATPase family associated with various cellular activities (AAA) |
| 2 | PF07728.16 | 0.67 | 6 | 174 | same-strand | AAA domain (dynein-related subfamily) |
| 3 | PF01556.20 | 0.89 | 8 | -13.0 | same-strand | DnaJ C terminal domain |
| 4 | PF00226.33 | 1.0 | 9 | -13 | same-strand | DnaJ domain |
| 5 | PF01025.21 | 1.0 | 9 | 832 | same-strand | GrpE |
| 6 | PF00012.22 | 0.89 | 8 | 1438.5 | same-strand | Hsp70 protein |
| 7 | PF01434.20 | 0.89 | 8 | 3400.5 | opposite-strand | Peptidase family M41 |
| 8 | PF17862.3 | 0.89 | 8 | 3400.5 | opposite-strand | AAA+ lid domain |
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