Result : P76334
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Cell division protein DrpB (Division ring protein B) |
| NCBI Accession ID | |
| Organism | Escherichia coli (strain K12) |
| Left | |
| Right | |
| Strand | |
| Nucleotide Sequence | |
| Sequence | MEYGSTKMEERLSRSPGGKLALWAFYTWCGYFVWAMARYIWVMSRIPDAPVSGFESDLGSTAGKWLGALVGFLFMALVGALLGSIAWYTRPRPARSRRYE |
| Source of smORF | Swiss-Prot |
| Function | A non-essential division protein that localizes to the septal ring in low ionic strength medium. {ECO:0000255|HAMAP-Rule:MF_00857}.; Localizes to the septal ring in about 30% of observed cells before cell constriction occurs; localization occurs in low ionic strength medium (0 NaCl) and requires FtsZ but not FtsEX. Overexpression partially restores correct FtsI localization to the division septum in an ftsEX deletion. Isolated as a multicopy suppressor of an ftsEX deletion mutant; it does not suppress other cell division defects (e.g. ftsA, ftsI, ftsQ or ftsZ). {ECO:0000269|Pubmed:32900831}. |
| Pubmed ID | 9278503 16738553 15919996 32900831 |
| Domain | |
| Functional Category | Others |
| Uniprot ID | P76334 |
| ORF Length (Amino Acid) | 100 |
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| Conservation Analysis |
No. of Species: 31
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 2033119 | 2033421 | - | NC_000913.3 | Escherichia coli str. K-12 substr. MG1655 |
| 2 | 2621352 | 2621654 | - | NZ_CP061527.1 | Shigella dysenteriae |
| 3 | 2596654 | 2596956 | - | NZ_LR134340.1 | Escherichia marmotae |
| 4 | 1962122 | 1962424 | - | NZ_AP014857.1 | Escherichia albertii |
| 5 | 982547 | 982816 | - | NZ_CP057657.1 | Escherichia fergusonii |
| 6 | 3029699 | 3029968 | - | NZ_CP009756.1 | Enterobacter cloacae |
| 7 | 1958018 | 1958299 | + | NZ_CP046672.1 | Raoultella ornithinolytica |
| 8 | 5308639 | 5308920 | - | NZ_CP026047.1 | Raoultella planticola |
| 9 | 1895430 | 1895711 | + | NZ_CP041247.1 | Raoultella electrica |
| 10 | 2152251 | 2152532 | + | NZ_CP060111.1 | Klebsiella michiganensis |
| 11 | 2931640 | 2931909 | - | NC_015968.1 | Enterobacter soli |
| 12 | 2230560 | 2230841 | + | NZ_CP036175.1 | Klebsiella huaxiensis |
| 13 | 2797784 | 2798056 | - | NZ_CP012871.1 | [Enterobacter] lignolyticus |
| 14 | 1730840 | 1731112 | + | NZ_CP013990.1 | Leclercia adecarboxylata |
| 15 | 1748100 | 1748381 | + | NZ_CP045845.1 | Kluyvera intermedia |
| 16 | 2144636 | 2144905 | - | NC_013716.1 | Citrobacter rodentium ICC168 |
| 17 | 1854190 | 1854471 | + | NZ_CP054254.1 | Klebsiella variicola |
| 18 | 1786144 | 1786425 | + | NZ_CP065838.1 | Klebsiella quasipneumoniae |
| 19 | 144019 | 144282 | - | NZ_CP042941.1 | Atlantibacter hermannii |
| 20 | 1919637 | 1919918 | + | NZ_LR134475.1 | Klebsiella aerogenes |
| 21 | 3424436 | 3424711 | - | NC_016845.1 | Klebsiella pneumoniae subsp. pneumoniae HS11286 |
| 22 | 4289977 | 4290267 | - | NZ_LT556085.1 | Citrobacter amalonaticus |
| 23 | 2009854 | 2010135 | + | NZ_CP050508.1 | Raoultella terrigena |
| 24 | 2643680 | 2643970 | + | NZ_CP045205.1 | Citrobacter telavivensis |
| 25 | 2076617 | 2076883 | - | NC_003197.2 | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |
| 26 | 1662488 | 1662760 | + | NZ_LR134201.1 | Cedecea lapagei |
| 27 | 1740182 | 1740454 | + | NZ_CP023525.1 | Cedecea neteri |
| 28 | 1600551 | 1600814 | + | NC_017910.1 | Shimwellia blattae DSM 4481 = NBRC 105725 |
| 29 | 85865 | 86131 | - | NZ_CP053416.1 | Salmonella bongori |
| 30 | 1729647 | 1729895 | + | NZ_AP023184.1 | Buttiauxella agrestis |
| 31 | 4493507 | 4493770 | - | NZ_CP040428.1 | Jejubacter calystegiae |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NZ_LR134340.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF05661.14 | 0.84 | 26 | 3771.0 | same-strand | Protein of unknown function (DUF808) |
| 2 | PF00892.22 | 0.87 | 27 | 2675 | opposite-strand | EamA-like transporter family |
| 3 | PF03852.17 | 0.9 | 28 | 2209.5 | same-strand | DNA mismatch endonuclease Vsr |
| 4 | PF00145.19 | 0.9 | 28 | 802.0 | same-strand | C-5 cytosine-specific DNA methylase |
| 5 | PF18284.3 | 0.9 | 28 | 802.0 | same-strand | DNA methylase N-terminal domain |
| 6 | PF01966.24 | 0.84 | 26 | 43.5 | same-strand | HD domain |
| 7 | PF00267.23 | 0.81 | 25 | 627.5 | opposite-strand | Gram-negative porin |
| 8 | PF06167.14 | 0.65 | 20 | 2271.0 | opposite-strand | Glucose-regulated metallo-peptidase M90 |
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