Result : P60326
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | DNA-directed RNA polymerase subunit omega (RNAP omega subunit) (EC 2.7.7.6) (RNA polymerase omega subunit) (Transcriptase subunit omega) |
| NCBI Accession ID | AE001439.1 |
| Organism | Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99) |
| Left | 792571 |
| Right | 792795 |
| Strand | - |
| Nucleotide Sequence | TTGAAAAAAGAGAGAACAGAGAGTTTAGTCGCTCAAGCCTTAAAAAATATTGGGAATGATCGCTACATGCTAGATAATTTGGTTTTCGCTCGTGTGAAGCAACTAAACGCTGGAGCCAAAACTTTAGTGAATATGGACCCTAAGCGTCATAAATTAGTGGATATTGCTATCAGAGAAATCGCTGAAGGGAAAATTGATATAGACAGGATAGATGAACGAAATTGA |
| Sequence | MKKERTESLVAQALKNIGNDRYMLDNLVFARVKQLNAGAKTLVNMDPKRHKLVDIAIREIAEGKIDIDRIDERN |
| Source of smORF | Swiss-Prot |
| Function | Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). {ECO:0000250}. |
| Pubmed ID | 9923682 |
| Domain | CDD:417484 |
| Functional Category | Others |
| Uniprot ID | P60326 |
| ORF Length (Amino Acid) | 74 |
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| Conservation Analysis |
No. of Species: 13
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 559034 | 559258 | + | NC_008229.1 | Helicobacter acinonychis str. Sheeba |
| 2 | 780211 | 780435 | - | NC_017379.1 | Helicobacter pylori Puno135 |
| 3 | 1491937 | 1492161 | - | NC_017735.1 | Helicobacter cetorum MIT 99-5656 |
| 4 | 810521 | 810745 | - | NC_004917.1 | Helicobacter hepaticus ATCC 51449 |
| 5 | 363036 | 363260 | - | NZ_AP018676.1 | Helicobacter cinaedi |
| 6 | 238044 | 238250 | + | NC_005090.1 | Wolinella succinogenes DSM 1740 |
| 7 | 244275 | 244499 | + | NZ_LN907858.1 | Helicobacter typhlonius |
| 8 | 330711 | 330929 | - | NC_014810.2 | Helicobacter felis ATCC 49179 |
| 9 | 681562 | 681771 | + | NZ_LS483446.1 | Helicobacter mustelae |
| 10 | 1198595 | 1198816 | - | NZ_CP014991.1 | Helicobacter himalayensis |
| 11 | 1045910 | 1046113 | - | NZ_CP063087.1 | Helicobacter winghamensis |
| 12 | 862639 | 862848 | + | NC_014935.1 | Nitratifractor salsuginis DSM 16511 |
| 13 | 647959 | 648177 | + | NZ_CP012544.1 | Campylobacter showae |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NC_017379.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF00696.30 | 0.92 | 12 | 43.0 | same-strand | Amino acid kinase family |
| 2 | PF13328.8 | 1.0 | 13 | 10 | same-strand | HD domain |
| 3 | PF04607.19 | 1.0 | 13 | 10 | same-strand | Region found in RelA / SpoT proteins |
| 4 | PF02824.23 | 1.0 | 13 | 10 | same-strand | TGS domain |
| 5 | PF00579.27 | 1.0 | 13 | 2196 | same-strand | tRNA synthetases class I (W and Y) |
| 6 | PF01479.27 | 0.62 | 8 | 2192.5 | same-strand | S4 domain |
| 7 | PF03060.17 | 1.0 | 13 | 3408 | same-strand | Nitronate monooxygenase |
| 8 | PF01520.20 | 1.0 | 13 | 4498 | same-strand | N-acetylmuramoyl-L-alanine amidase |
| 9 | PF01966.24 | 0.92 | 12 | 10.0 | same-strand | HD domain |
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