Result : P58091
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Antitoxin ParD1 |
| NCBI Accession ID | AE005673.1 |
| Organism | Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) |
| Left | 968965 |
| Right | 969231 |
| Strand | - |
| Nucleotide Sequence | ATGGCGAGCAAGAACACCTCCGTCGTCCTGGGCGATCACTTCCAGGCGTTCATCGACAGCCAGGTCGCTGACGGGCGCTACGGCTCGGCCAGCGAAGTCATCCGCGCGGGGCTGAGGCTCCTCGAAGAGAACGAAGCGAAGCTCGCGGCCCTCCGCGCCGCCCTGATCGAAGGCGAGGAGAGCGGCTTTATCGAGGACTTCGACTTCGACGCCTTTATCGAGGAAAGGTCTAGGGCATCCGCTCCGCAGGGGTTCCATGAGGAATGA |
| Sequence | MASKNTSVVLGDHFQAFIDSQVADGRYGSASEVIRAGLRLLEENEAKLAALRAALIEGEESGFIEDFDFDAFIEERSRASAPQGFHEE |
| Source of smORF | Swiss-Prot |
| Function | Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE1, but no other RelE or ParE toxin. May act as a DNA gyrase inhibitor (By similarity). {ECO:0000250, ECO:0000269|Pubmed:20487277}. |
| Pubmed ID | 11259647 15718296 20487277 20143871 |
| Domain | CDD:419885,CDD:425357 |
| Functional Category | Antitoxin_type_2 |
| Uniprot ID | P58091 |
| ORF Length (Amino Acid) | 88 |
++ More..
| Conservation Analysis |
No. of Species: 115
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 994996 | 995262 | - | NC_011916.1 | Caulobacter vibrioides NA1000 |
| 2 | 771505 | 771750 | + | NC_009719.1 | Parvibaculum lavamentivorans DS-1 |
| 3 | 816794 | 817018 | + | NZ_CP027668.1 | Phreatobacter cathodiphilus |
| 4 | 452006 | 452251 | - | NZ_CP053923.1 | Defluviicoccus vanus |
| 5 | 179754 | 180002 | - | NZ_CP054025.1 | Rhizobium indicum |
| 6 | 2256955 | 2257212 | - | NZ_CP026100.1 | Caulobacter flavus |
| 7 | 294172 | 294417 | - | NZ_CP045073.1 | Paracoccus kondratievae |
| 8 | 1185143 | 1185388 | - | NZ_CP045073.1 | Paracoccus kondratievae |
| 9 | 696632 | 696877 | - | NZ_CP045072.1 | Paracoccus kondratievae |
| 10 | 549934 | 550179 | + | NZ_CP017147.1 | Bosea vaviloviae |
| 11 | 3739451 | 3739702 | + | NZ_CP027850.1 | Caulobacter segnis |
| 12 | 1465490 | 1465735 | + | NC_020059.1 | Rhizobium tropici CIAT 899 |
| 13 | 301213 | 301485 | - | NZ_CP019240.1 | Rhodoferax antarcticus |
| 14 | 1749691 | 1749948 | + | NZ_CP024422.1 | Paracoccus yeei |
| 15 | 701552 | 701794 | + | NZ_CP022742.1 | Vibrio qinghaiensis |
| 16 | 703174 | 703416 | + | NZ_CP022742.1 | Vibrio qinghaiensis |
| 17 | 421160 | 421408 | - | NZ_CP071681.1 | Rhizobium ruizarguesonis |
| 18 | 1228105 | 1228329 | - | NZ_AP019700.1 | Stella humosa |
| 19 | 4157740 | 4157979 | - | NZ_CP020931.1 | Marinobacter salarius |
| 20 | 1811351 | 1811569 | + | NZ_CP044069.1 | Vibrio vulnificus |
| 21 | 1859406 | 1859624 | + | NZ_CP044069.1 | Vibrio vulnificus |
| 22 | 1250585 | 1250827 | + | NZ_CP009355.1 | Vibrio tubiashii ATCC 19109 |
| 23 | 2016638 | 2016871 | - | NZ_CP060789.1 | Tessaracoccus defluvii |
| 24 | 483470 | 483712 | - | NZ_CP061081.1 | Marinomonas arctica |
| 25 | 2421469 | 2421711 | - | NZ_CP019875.1 | Komagataeibacter nataicola |
| 26 | 3466944 | 3467186 | + | NZ_CP050139.1 | Komagataeibacter rhaeticus |
| 27 | 347919 | 348161 | - | NZ_AP014525.1 | Vibrio cholerae MS6 |
| 28 | 1867327 | 1867545 | + | NZ_CP043869.1 | Neptunomonas concharum |
| 29 | 777103 | 777348 | - | NZ_AP014636.1 | Vibrio tritonius |
| 30 | 5133 | 5381 | - | NZ_AP014570.1 | Serpentinomonas mccroryi |
| 31 | 3612165 | 3612404 | + | NZ_CP021425.1 | Oleiphilus messinensis |
| 32 | 831324 | 831557 | - | NC_018010.1 | Belliella baltica DSM 15883 |
| 33 | 2118058 | 2118288 | - | NZ_AP022562.1 | Mycobacterium novum |
| 34 | 4492543 | 4492773 | + | NC_015576.1 | Mycolicibacter sinensis |
| 35 | 2558045 | 2558284 | + | NC_017857.3 | Methylophaga nitratireducenticrescens |
| 36 | 1719204 | 1719449 | + | NZ_CP032694.1 | Rhizobium jaguaris |
| 37 | 3557935 | 3558186 | - | NZ_CP020809.1 | Mycobacterium dioxanotrophicus |
| 38 | 1582199 | 1582417 | - | NC_011753.2 | Vibrio atlanticus |
| 39 | 36063 | 36302 | - | NZ_CP041661.1 | Catenovulum sediminis |
| 40 | 2772737 | 2772979 | - | NC_010814.1 | Geobacter lovleyi SZ |
| 41 | 480685 | 480927 | + | NZ_CP035689.1 | Vibrio metoecus |
| 42 | 2749911 | 2750144 | + | NZ_LT906473.1 | Corynebacterium cystitidis |
| 43 | 2543433 | 2543684 | - | NZ_CP011971.1 | Steroidobacter denitrificans |
| 44 | 185478 | 185720 | + | NZ_CP017565.1 | Paraburkholderia sprentiae WSM5005 |
| 45 | 12387 | 12626 | - | NZ_CP027860.1 | Ahniella affigens |
| 46 | 1179008 | 1179250 | - | NZ_AP014568.1 | Serpentinomonas raichei |
| 47 | 90551 | 90802 | - | NC_022654.1 | Mycobacterium kansasii ATCC 12478 |
| 48 | 2659286 | 2659531 | - | NZ_CP014056.2 | Grimontia hollisae |
| 49 | 11985 | 12230 | + | NZ_CP040756.1 | Paracoccus liaowanqingii |
| 50 | 1858258 | 1858503 | + | NZ_CP013450.1 | Burkholderia cenocepacia |
| 51 | 3102955 | 3103194 | + | NZ_CP019628.1 | Pseudoalteromonas aliena |
| 52 | 296679 | 296921 | - | NC_004757.1 | Nitrosomonas europaea ATCC 19718 |
| 53 | 4623020 | 4623259 | + | NZ_CP020465.1 | Cognaticolwellia beringensis |
| 54 | 3097607 | 3097852 | + | NZ_CP011503.1 | Burkholderia pyrrocinia |
| 55 | 954138 | 954383 | - | NZ_CP012040.1 | Cyclobacterium amurskyense |
| 56 | 1026651 | 1026896 | - | NC_015914.1 | Cyclobacterium marinum DSM 745 |
| 57 | 72518 | 72766 | + | NC_020560.1 | Sinorhizobium meliloti 2011 |
| 58 | 3554180 | 3554404 | + | NZ_CP060092.1 | Teredinibacter purpureus |
| 59 | 1112361 | 1112585 | - | NZ_CP060092.1 | Teredinibacter purpureus |
| 60 | 685400 | 685624 | - | NZ_CP060084.1 | Teredinibacter haidensis |
| 61 | 291642 | 291884 | + | NZ_CP051461.1 | Polaromonas vacuolata |
| 62 | 8809 | 9057 | + | NZ_CP064064.1 | Brucella anthropi |
| 63 | 555817 | 556059 | - | NZ_CP040022.1 | Salinivibrio kushneri |
| 64 | 2203974 | 2204225 | - | NC_000962.3 | Mycobacterium tuberculosis H37Rv |
| 65 | 840834 | 841085 | + | NZ_CP018911.1 | Glycocaulis alkaliphilus |
| 66 | 535478 | 535711 | + | NZ_CP031941.1 | Nostoc sphaeroides |
| 67 | 4313008 | 4313250 | - | NC_005125.1 | Gloeobacter violaceus PCC 7421 |
| 68 | 1459168 | 1459407 | + | NZ_CP072844.1 | Psychrosphaera aestuarii |
| 69 | 522594 | 522833 | + | NZ_CP011036.1 | Pseudoalteromonas nigrifaciens |
| 70 | 3699827 | 3700060 | - | NZ_CP054698.1 | Nostoc edaphicum CCNP1411 |
| 71 | 943334 | 943585 | - | NZ_CP007202.1 | Siansivirga zeaxanthinifaciens CC-SAMT-1 |
| 72 | 2984026 | 2984268 | - | NC_015321.1 | Fluviicola taffensis DSM 16823 |
| 73 | 1355437 | 1355682 | + | NZ_CP009831.1 | Burkholderia multivorans ATCC BAA-247 |
| 74 | 554702 | 554953 | + | NZ_CP037755.1 | Pseudocnuella soli |
| 75 | 488830 | 489060 | - | NZ_CP037755.1 | Pseudocnuella soli |
| 76 | 2148676 | 2148933 | + | NZ_AP022615.1 | Mycobacterium heidelbergense |
| 77 | 2247984 | 2248235 | - | NC_015848.1 | Mycobacterium canettii CIPT 140010059 |
| 78 | 1851484 | 1851735 | + | NZ_AP022613.1 | Mycobacterium conspicuum |
| 79 | 628934 | 629176 | + | NZ_CP008849.1 | Alteromonas australica |
| 80 | 4749089 | 4749340 | + | NZ_AP022616.1 | Mycolicibacterium phocaicum |
| 81 | 44160 | 44405 | - | NZ_CP035902.1 | Burkholderia glumae |
| 82 | 3653263 | 3653508 | - | NZ_CP019419.1 | Polaribacter reichenbachii |
| 83 | 1410295 | 1410519 | + | NZ_CP047045.1 | Terricaulis silvestris |
| 84 | 2326141 | 2326383 | - | NZ_CP046670.1 | Alteromonas mediterranea |
| 85 | 245601 | 245840 | - | NZ_CP004387.1 | Alcanivorax pacificus W11-5 |
| 86 | 4481356 | 4481607 | + | NZ_CP009360.4 | Mycobacterium avium subsp. hominissuis |
| 87 | 638383 | 638598 | + | NZ_AP012273.1 | Thiolapillus brandeum |
| 88 | 2751187 | 2751429 | + | NZ_CP029186.1 | Flavobacterium album |
| 89 | 3258040 | 3258279 | - | NZ_CP013189.1 | Pseudohongiella spirulinae |
| 90 | 803381 | 803620 | + | NZ_CP042218.1 | Luteimonas granuli |
| 91 | 1206246 | 1206464 | - | NZ_CP038810.1 | Flavobacterium sangjuense |
| 92 | 4675 | 4920 | + | NC_017957.2 | Tistrella mobilis KA081020-065 |
| 93 | 1134389 | 1134637 | + | NZ_CP029255.1 | Flavobacterium crocinum |
| 94 | 3366701 | 3366928 | + | NZ_CP047984.1 | Pontibacter russatus |
| 95 | 2586388 | 2586603 | + | NZ_CP045571.1 | Acidithiobacillus thiooxidans ATCC 19377 |
| 96 | 2762962 | 2763210 | - | NZ_CP041637.1 | Formosa sediminum |
| 97 | 1560310 | 1560558 | - | NC_014041.1 | Zunongwangia profunda SM-A87 |
| 98 | 1733985 | 1734236 | - | NC_014759.1 | Marivirga tractuosa DSM 4126 |
| 99 | 3804718 | 3804969 | - | NZ_AP022563.1 | Mycolicibacterium duvalii |
| 100 | 4271095 | 4271346 | - | NZ_CP025791.1 | Flavivirga eckloniae |
| 101 | 2506647 | 2506889 | + | NC_008571.1 | Gramella forsetii KT0803 |
| 102 | 2960961 | 2961188 | - | NZ_CP033920.1 | Chryseobacterium carnipullorum |
| 103 | 2037571 | 2037813 | - | NZ_CP013355.1 | Lutibacter profundi |
| 104 | 161549 | 161773 | + | NZ_CP053698.1 | Empedobacter stercoris |
| 105 | 1540820 | 1541044 | - | NZ_CP053698.1 | Empedobacter stercoris |
| 106 | 2690674 | 2690898 | + | NZ_CP053698.1 | Empedobacter stercoris |
| 107 | 3260161 | 3260388 | - | NZ_CP039934.1 | Myroides fluvii |
| 108 | 1235645 | 1235878 | + | NZ_AP017369.1 | Corynebacterium suranareeae |
| 109 | 279343 | 279570 | + | NZ_CP015067.2 | Elizabethkingia anophelis |
| 110 | 2347413 | 2347664 | - | NZ_CP014337.1 | Elizabethkingia bruuniana |
| 111 | 638930 | 639178 | + | NC_013960.1 | Nitrosococcus halophilus Nc 4 |
| 112 | 2566487 | 2566723 | - | NC_015675.1 | Mesorhizobium opportunistum WSM2075 |
| 113 | 1457067 | 1457297 | - | NZ_CP022111.1 | Nitrospirillum amazonense CBAmc |
| 114 | 2171249 | 2171482 | + | NZ_CP035806.1 | Leucobacter triazinivorans |
| 115 | 4614786 | 4615028 | + | NC_015844.1 | Zobellia galactanivorans |
| 116 | 2725616 | 2725864 | + | NC_014315.1 | Nitrosococcus watsonii C-113 |
| 117 | 4636869 | 4637114 | + | NZ_CP018171.1 | Mesorhizobium oceanicum |
| 118 | 2889917 | 2890174 | - | NZ_CP017477.1 | Polaribacter vadi |
| 119 | 1335305 | 1335529 | - | NZ_CP012836.1 | Algoriphagus sanaruensis |
| 120 | 1339813 | 1340064 | + | NZ_AP022570.1 | Mycolicibacterium poriferae |
| 121 | 3082502 | 3082744 | + | NZ_CP020822.1 | Tenacibaculum maritimum |
| 122 | 600790 | 601032 | + | NZ_CP061703.1 | Mesoflavibacter profundi |
| 123 | 5467026 | 5467274 | - | NC_009441.1 | Flavobacterium johnsoniae UW101 |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NC_011916.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF05016.17 | 0.82 | 94 | -3.0 | same-strand | ParE toxin of type II toxin-antitoxin system, parDE |
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