| Protein name |
Lantibiotic actagardine (Gardimycin) |
| NCBI Accession ID |
FJ547091.1 |
| Organism |
Actinoplanes garbadinensis |
| Left |
21572 |
| Right |
21766 |
| Strand |
+ |
| Nucleotide Sequence |
ATGTCTGCTCTCGCCATCGAGAAGTCCTGGAAGGACGTCGACCTCCGTGACGGGGCGACCAGCCACCCGGCCGGCCTCGGCTTCGGCGAGCTCACCTTCGAGGACCTTCGCGAGGACCGCACCATCTACGCCGCCAGCAGCGGCTGGGTGTGCACCCTGACGATCGAGTGCGGCACCGTGATCTGCGCCTGCTGA |
| Sequence |
MSALAIEKSWKDVDLRDGATSHPAGLGFGELTFEDLREDRTIYAASSGWVCTLTIECGTVICAC |
| Source of smORF |
Swiss-Prot |
| Function |
Has potent antibacterial activity against some Gram-positive bacteria (Pubmed:19400806). Has good antistreptococcal activity. Inhibits cell wall biosynthesis by binding to lipid II and blocking transglycosylation (Pubmed:9449277). {ECO:0000269|Pubmed:19400806, ECO:0000269|Pubmed:9449277}. |
| Pubmed ID |
19400806
2211371
7737178
9449277
9219543
|
| Domain |
|
| Functional Category |
Antimicrobial |
| Uniprot ID |
P56650
|
| ORF Length (Amino Acid) |
64 |