| Protein name |
Lantibiotic mersacidin |
| NCBI Accession ID |
Z47559.1 |
| Organism |
Bacillus sp. (strain HIL-Y85/54728) |
| Left |
22 |
| Right |
228 |
| Strand |
+ |
| Nucleotide Sequence |
ATGAGTCAAGAAGCTATCATTCGTTCATGGAAAGATCCTTTTTCCCGTGAAAATTCTACACAAAATCCAGCTGGTAACCCATTCAGTGAGCTGAAAGAAGCACAAATGGATAAGTTAGTAGGTGCGGGAGACATGGAAGCAGCATGTACTTTTACATTGCCTGGTGGCGGCGGTGTTTGTACTCTAACTTCTGAATGTATTTGTTAA |
| Sequence |
MSQEAIIRSWKDPFSRENSTQNPAGNPFSELKEAQMDKLVGAGDMEAACTFTLPGGGGVCTLTSECIC |
| Source of smORF |
Swiss-Prot |
| Function |
Kills a number of Gram-positive bacteria. Acts at the level of cell wall biosynthesis by interfering with bacterial peptidoglycan biosynthesis. Specifically inhibits the conversion of the lipid II intermediate into polymeric nascent glycan strands by transglycosylation. May interact with the peptidoglycan precursor rather than with the enzyme. |
| Pubmed ID |
7737474
10831439
9210483
9119018
10818347
|
| Domain |
CDD:333722,CDD:304651 |
| Functional Category |
Antimicrobial |
| Uniprot ID |
P43683
|
| ORF Length (Amino Acid) |
68 |