Result : P33229
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Endodeoxyribonuclease toxin RalR (DNase RalR) (EC 3.1.-.-) (Restriction alleviation and modification enhancement protein) (Toxin RalR) |
| NCBI Accession ID | U00096.3 |
| Organism | Escherichia coli (strain K12) |
| Left | 1413733 |
| Right | 1413927 |
| Strand | - |
| Nucleotide Sequence | ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCGAGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAACCACTGGAAATAATAATGGAGGTGTTCATGTATAA |
| Sequence | MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV |
| Source of smORF | Swiss-Prot |
| Function | Toxic component of a type I toxin-antitoxin (TA) system. Upon overexpression inhibits growth and reduces colony-forming units in both the presence and absence of the Rac prophage, cells become filamentous. Has deoxyribonuclease activity (probably endonucleolytic), does not digest RNA. Its toxic effects are neutralized by sRNA antitoxin RalA, which is encoded in trans on the opposite DNA strand (Pubmed:24748661). Has RAL-like activity (Pubmed:7476171). {ECO:0000269|Pubmed:24748661, ECO:0000269|Pubmed:7476171}. |
| Pubmed ID | 8244937 9097039 9278503 16738553 7476171 24748661 |
| Domain | CDD:415457 |
| Functional Category | Toxin_type_1 |
| Uniprot ID | P33229 |
| ORF Length (Amino Acid) | 64 |
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| Conservation Analysis |
No. of Species: 4
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 1413733 | 1413927 | - | NC_000913.3 | Escherichia coli str. K-12 substr. MG1655 |
| 2 | 2344109 | 2344303 | + | NZ_LR134340.1 | Escherichia marmotae |
| 3 | 102910 | 103107 | + | NZ_CP045203.1 | Citrobacter telavivensis |
| 4 | 255391 | 255588 | + | NZ_CP041248.1 | Raoultella electrica |
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