Result : P0C077
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | mRNA interferase toxin RelE (EC 3.1.-.-) (Endoribonuclease RelE) (Toxin RelE) |
| NCBI Accession ID | X02405.1 |
| Organism | Escherichia coli (strain K12) |
| Left | 733 |
| Right | 1020 |
| Strand | + |
| Nucleotide Sequence | ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAAAAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTAAGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAAAGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA |
| Sequence | MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGKRERSEVYSEAVKRIL |
| Source of smORF | Swiss-Prot |
| Function | Toxic component of a type II toxin-antitoxin (TA) system (Pubmed:9767574). A sequence-specific, ribosome-dependent mRNA endoribonuclease that inhibits translation during amino acid starvation (the stringent response). In vitro acts by cleaving mRNA with high codon specificity in the ribosomal A site between positions 2 and 3. The stop codon UAG is cleaved at a fast rate while UAA and UGA are cleaved with intermediate and slow rates. In vitro mRNA cleavage can also occur in the ribosomal E site after peptide release from peptidyl-tRNA in the P site as well as on free 30S subunits (Pubmed:12526800). In vivo cuts frequently in the first 100 codons, most frequently after the second and third base and rarely near the stop codon (Pubmed:21324908). Overexpression of RelE results in the inhibition of bacterial growth and a sharp decrease in colony-forming ability which is neutralized by the labile cognate antitoxin RelB. Overexpression also sharply increases persisters (cells that neither grow nor die in the presence of bactericidal agents and are largely responsible for high levels of biofilm tolerance to antimicrobials) (Pubmed:15576765). mRNA interferases play a role in bacterial persistence to antibiotics; overexpression of this protein induces persisters resistant to ciprofloxacin and ampicillin (Pubmed:21788497). Plays a role in dormancy when expressed in high-density cells in the absence of antitoxin RelB; amino acid starvation and an unidentified extracellular factor promote dormancy, while expression of antitoxin RelB restores cell culturability (Pubmed:22210768). Acts with RelB as a corepressor of relBE transcription, considerably increasing the repression of RelB alone. 2 RelB dimers bind to 2 operator sequences; DNA-binding and repression is stronger when complexed with toxin/corepressor RelE by conditional cooperativity (Pubmed:9767574, Pubmed:19747491, Pubmed:18501926, Pubmed:22981948). {ECO:0000269|Pubmed:11274135, ECO:0000269|Pubmed:11717402, ECO:0000269|Pubmed:12123459, ECO:0000269|Pubmed:12526800, ECO:0000269|Pubmed:15576765, ECO:0000269|Pubmed:18501926, ECO:0000269|Pubmed:18532983, ECO:0000269|Pubmed:19747491, ECO:0000269|Pubmed:20005802, ECO:0000269|Pubmed:21324908, ECO:0000269|Pubmed:21788497, ECO:0000269|Pubmed:22210768, ECO:0000269|Pubmed:22981948, ECO:0000269|Pubmed:24251350, ECO:0000269|Pubmed:9767574}.; Seems to be a principal mediator of cell death in liquid media (Pubmed:19707553). Implicated in hydroxy radical-mediated cell death induced by hydroxyurea treatment (Pubmed:20005847). {ECO:0000269|Pubmed:19707553, ECO:0000269|Pubmed:20005847}.; Cross-talk can occur between different TA systems. Ectopic expression of this toxin induces transcription of 7 tested TA systems (dinJ/yafQ, hicAB, mazEF, mqsRA, prlF(sohA)/yhaV, relBEF and yefM/yoeB) with specific cleavage of the relBEF mRNA produced immediately upstream and within the relB coding sequence. The cleaved mRNA can be translated into RelE, leading to a positive feedback cycle of RelE expression. The relBEF operon is required for transcription of the mazEF TA system operon during amino acid starvation. {ECO:0000269|Pubmed:23432955}. |
| Pubmed ID | 2990907 9097039 9278503 16738553 9767574 11274135 11717402 12123459 12526800 15576765 19707553 18501926 18532983 19747491 20005847 21324908 21788497 22210768 23432955 24251350 19215780 20005802 19297318 22981948 |
| Domain | CDD:419697 |
| Functional Category | RNA-binding_and_Toxin_type_2 |
| Uniprot ID | P0C077 |
| ORF Length (Amino Acid) | 95 |
++ More..
| Conservation Analysis |
No. of Species: 190
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 58770 | 59057 | - | NZ_CP011600.1 | Phytobacter ursingii |
| 2 | 25884 | 26171 | - | NZ_CP011601.1 | Phytobacter ursingii |
| 3 | 240462 | 240749 | - | NZ_CP061512.1 | Mixta calida |
| 4 | 1581699 | 1581986 | - | NC_004337.2 | Shigella flexneri 2a str. 301 |
| 5 | 1645346 | 1645633 | - | NC_000913.3 | Escherichia coli str. K-12 substr. MG1655 |
| 6 | 2721975 | 2722262 | + | NZ_CP050508.1 | Raoultella terrigena |
| 7 | 1493177 | 1493464 | + | NC_017910.1 | Shimwellia blattae DSM 4481 = NBRC 105725 |
| 8 | 91652 | 91939 | + | NZ_CP033743.1 | Citrobacter freundii |
| 9 | 2893832 | 2894119 | - | NZ_CP054058.1 | Scandinavium goeteborgense |
| 10 | 1790363 | 1790656 | - | NZ_CP027756.1 | Pseudomonas synxantha |
| 11 | 3991381 | 3991671 | + | NZ_CP009365.1 | Pseudomonas soli |
| 12 | 115170 | 115457 | - | NZ_CP034150.1 | Pantoea agglomerans |
| 13 | 150743 | 151030 | + | NZ_CP034150.1 | Pantoea agglomerans |
| 14 | 6063711 | 6064013 | + | NZ_CP014870.1 | Pseudomonas silesiensis |
| 15 | 91546 | 91827 | + | NZ_CP014870.1 | Pseudomonas silesiensis |
| 16 | 2216668 | 2216955 | - | NZ_CP031146.1 | Pseudomonas plecoglossicida |
| 17 | 541529 | 541813 | + | NZ_CP063425.1 | Kosakonia pseudosacchari |
| 18 | 4052290 | 4052574 | + | NC_015554.1 | Alteromonas naphthalenivorans |
| 19 | 4540314 | 4540601 | - | NZ_CP022562.1 | Pseudomonas monteilii |
| 20 | 3528032 | 3528316 | - | NZ_CP022562.1 | Pseudomonas monteilii |
| 21 | 2721750 | 2722034 | + | NZ_CP023567.1 | Erwinia pyrifoliae |
| 22 | 2729399 | 2729683 | + | NZ_CP023567.1 | Erwinia pyrifoliae |
| 23 | 533081 | 533365 | - | NZ_CP023567.1 | Erwinia pyrifoliae |
| 24 | 525432 | 525716 | - | NZ_CP023567.1 | Erwinia pyrifoliae |
| 25 | 981267 | 981554 | + | NZ_CP023567.1 | Erwinia pyrifoliae |
| 26 | 5312836 | 5313120 | + | NZ_CP014782.1 | Shewanella psychrophila |
| 27 | 1744623 | 1744907 | - | NZ_LR134494.1 | Serratia quinivorans |
| 28 | 488755 | 489039 | + | NZ_AP022508.1 | Enterobacter bugandensis |
| 29 | 1339995 | 1340282 | - | NZ_CP020388.1 | Pluralibacter gergoviae |
| 30 | 762334 | 762618 | + | NZ_CP047495.1 | Pectobacterium brasiliense |
| 31 | 1485246 | 1485533 | + | NZ_CP047495.1 | Pectobacterium brasiliense |
| 32 | 1083321 | 1083605 | + | NZ_CP051652.1 | Pectobacterium carotovorum |
| 33 | 4753144 | 4753431 | + | NZ_CP051652.1 | Pectobacterium carotovorum |
| 34 | 2260622 | 2260906 | + | NZ_CP015750.1 | Pectobacterium wasabiae CFBP 3304 |
| 35 | 2152573 | 2152860 | + | NZ_CP015750.1 | Pectobacterium wasabiae CFBP 3304 |
| 36 | 3306319 | 3306603 | + | NZ_CP014137.1 | Brenneria goodwinii |
| 37 | 6119030 | 6119320 | - | NC_004578.1 | Pseudomonas syringae pv. tomato str. DC3000 |
| 38 | 4272100 | 4272384 | + | NZ_CP017482.1 | Pectobacterium polaris |
| 39 | 3850459 | 3850746 | - | NZ_CP017482.1 | Pectobacterium polaris |
| 40 | 4152418 | 4152705 | + | NZ_CP017482.1 | Pectobacterium polaris |
| 41 | 347267 | 347554 | - | NZ_CP007030.1 | Thiomicrospira aerophila AL3 |
| 42 | 4784 | 5065 | - | NC_013718.1 | Citrobacter rodentium ICC168 |
| 43 | 3023273 | 3023557 | - | NZ_CP045769.1 | Enterobacter cancerogenus |
| 44 | 1996659 | 1996988 | + | NZ_LR134167.1 | Avibacterium volantium |
| 45 | 1066371 | 1066655 | + | NZ_CP034036.1 | Brenneria nigrifluens DSM 30175 = ATCC 13028 |
| 46 | 3688857 | 3689171 | - | NZ_CP068551.1 | Pseudomonas khazarica |
| 47 | 845322 | 845645 | - | NZ_AP022642.1 | Pseudomonas otitidis |
| 48 | 5760706 | 5760996 | - | NZ_CP068034.2 | Pseudomonas syringae |
| 49 | 316801 | 317088 | - | NZ_CP060009.1 | Pseudomonas sediminis |
| 50 | 807290 | 807574 | - | NZ_CP009125.1 | Pectobacterium atrosepticum |
| 51 | 78934 | 79221 | - | NZ_CP009125.1 | Pectobacterium atrosepticum |
| 52 | 3688682 | 3688966 | + | NZ_CP016337.1 | Kosakonia sacchari |
| 53 | 3299014 | 3299298 | + | NZ_CP071320.1 | Serratia ureilytica |
| 54 | 1751468 | 1751752 | - | NZ_CP038662.1 | Serratia nematodiphila |
| 55 | 1892223 | 1892507 | + | NZ_CP037952.1 | Parashewanella spongiae |
| 56 | 2285829 | 2286113 | + | NZ_CP037952.1 | Parashewanella spongiae |
| 57 | 509945 | 510229 | + | NZ_CP027986.1 | Enterobacter sichuanensis |
| 58 | 4136017 | 4136301 | - | NZ_CP035129.1 | Kosakonia cowanii |
| 59 | 4813920 | 4814204 | - | NZ_CP014007.2 | Kosakonia oryzae |
| 60 | 3418043 | 3418333 | + | NZ_CP057657.1 | Escherichia fergusonii |
| 61 | 2913052 | 2913354 | + | NZ_CP061511.1 | Mixta calida |
| 62 | 4030425 | 4030712 | + | NZ_CP027107.1 | Cronobacter sakazakii |
| 63 | 3128571 | 3128861 | + | NC_012691.1 | Tolumonas auensis DSM 9187 |
| 64 | 612709 | 612990 | + | NC_012691.1 | Tolumonas auensis DSM 9187 |
| 65 | 374447 | 374734 | + | NZ_CP056030.1 | Pseudomonas eucalypticola |
| 66 | 582342 | 582632 | - | NZ_AP021889.1 | Thiosulfatimonas sediminis |
| 67 | 1824639 | 1824923 | - | NZ_AP021889.1 | Thiosulfatimonas sediminis |
| 68 | 2674073 | 2674363 | + | NC_002939.5 | Geobacter sulfurreducens PCA |
| 69 | 3271577 | 3271861 | + | NZ_CP033744.1 | Citrobacter freundii |
| 70 | 1846575 | 1846865 | + | NZ_CP032093.1 | Vibrio alfacsensis |
| 71 | 1803008 | 1803298 | + | NZ_CP044069.1 | Vibrio vulnificus |
| 72 | 85258 | 85548 | - | NZ_CP025792.1 | Vibrio jasicida 090810c |
| 73 | 5429526 | 5429816 | - | NZ_CP071706.1 | Pseudomonas donghuensis |
| 74 | 1547962 | 1548246 | + | NZ_CP061202.1 | Rhodobacter capsulatus |
| 75 | 347066 | 347356 | - | NZ_CP014055.2 | Grimontia hollisae |
| 76 | 492967 | 493257 | - | NZ_LT960611.1 | Vibrio tapetis subsp. tapetis |
| 77 | 75562 | 75843 | + | NZ_CP039701.1 | Vibrio cyclitrophicus |
| 78 | 1745777 | 1746058 | + | NZ_CP039700.1 | Vibrio cyclitrophicus |
| 79 | 3590975 | 3591259 | + | NZ_CP017279.1 | Enterobacter ludwigii |
| 80 | 777632 | 777883 | + | NZ_CP061081.1 | Marinomonas arctica |
| 81 | 2669698 | 2669985 | + | NZ_CP061081.1 | Marinomonas arctica |
| 82 | 860243 | 860560 | + | NZ_LR215729.2 | Pseudomonas marincola |
| 83 | 2070500 | 2070784 | - | NZ_CP070624.1 | Photobacterium damselae subsp. damselae |
| 84 | 777506 | 777796 | - | NZ_AP014636.1 | Vibrio tritonius |
| 85 | 776125 | 776415 | - | NZ_AP014636.1 | Vibrio tritonius |
| 86 | 1247102 | 1247392 | - | NZ_AP019657.1 | Vibrio ponticus |
| 87 | 1585901 | 1586185 | - | NC_011312.1 | Aliivibrio salmonicida LFI1238 |
| 88 | 1141981 | 1142265 | + | NZ_CP045205.1 | Citrobacter telavivensis |
| 89 | 4691698 | 4691982 | + | NC_003197.2 | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |
| 90 | 1626558 | 1626842 | - | NC_003197.2 | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |
| 91 | 34810 | 35106 | - | NZ_CP023525.1 | Cedecea neteri |
| 92 | 5296562 | 5296843 | + | NZ_CP014205.2 | Pseudomonas glycinae |
| 93 | 1171433 | 1171717 | - | NZ_LR134378.1 | Lautropia mirabilis |
| 94 | 816871 | 817194 | + | NZ_CP030241.1 | Moraxella bovis |
| 95 | 1006014 | 1006322 | - | NZ_CP030241.1 | Moraxella bovis |
| 96 | 2965037 | 2965324 | - | NZ_CP072844.1 | Psychrosphaera aestuarii |
| 97 | 2752263 | 2752553 | + | NZ_CP011078.1 | Yersinia ruckeri |
| 98 | 313631 | 313921 | - | NZ_CP016415.1 | Vibrio scophthalmi |
| 99 | 5242312 | 5242599 | + | NZ_CP049044.1 | Pseudomonas psychrophila |
| 100 | 22056 | 22343 | - | NZ_CP045299.1 | Kosakonia arachidis |
| 101 | 1281255 | 1281539 | + | NC_017187.1 | Aliarcobacter butzleri ED-1 |
| 102 | 3363324 | 3363611 | - | NZ_CP046293.1 | Yersinia intermedia |
| 103 | 2966926 | 2967216 | + | NZ_CP029640.1 | Paraburkholderia dokdonella |
| 104 | 2839746 | 2840030 | + | NZ_CP012023.1 | Celeribacter marinus |
| 105 | 1965633 | 1965923 | + | NZ_CP012023.1 | Celeribacter marinus |
| 106 | 3091902 | 3092192 | - | NZ_CP012023.1 | Celeribacter marinus |
| 107 | 2293862 | 2294149 | + | NZ_LN907827.1 | Erwinia gerundensis |
| 108 | 1328862 | 1329146 | - | NZ_CP053835.1 | Arcobacter defluvii |
| 109 | 523523 | 523807 | + | NC_016845.1 | Klebsiella pneumoniae subsp. pneumoniae HS11286 |
| 110 | 210237 | 210527 | + | NC_012962.1 | Photorhabdus asymbiotica |
| 111 | 3604175 | 3604462 | - | NC_012962.1 | Photorhabdus asymbiotica |
| 112 | 38918 | 39205 | + | NZ_CP026049.1 | Raoultella planticola |
| 113 | 3326804 | 3327085 | - | NZ_CP070503.1 | Pseudomonas atacamensis |
| 114 | 2837827 | 2838108 | - | NZ_CP013461.1 | Burkholderia stagnalis |
| 115 | 102969 | 103256 | - | NZ_CP038855.1 | Pantoea vagans |
| 116 | 1212146 | 1212436 | + | NZ_CP026111.1 | Paraburkholderia terrae |
| 117 | 3269810 | 3270100 | + | NZ_CP009781.1 | Yersinia aldovae 670-83 |
| 118 | 2601340 | 2601627 | + | NC_013173.1 | Desulfomicrobium baculatum DSM 4028 |
| 119 | 414546 | 414836 | - | NZ_AP014525.1 | Vibrio cholerae MS6 |
| 120 | 431062 | 431349 | + | NZ_AP014525.1 | Vibrio cholerae MS6 |
| 121 | 460530 | 460820 | + | NZ_CP035689.1 | Vibrio metoecus |
| 122 | 1065394 | 1065693 | - | NC_014836.1 | Desulfurispirillum indicum S5 |
| 123 | 4855551 | 4855838 | + | NZ_CP065044.1 | Pectobacterium aroidearum |
| 124 | 4555495 | 4555782 | - | NZ_CP065044.1 | Pectobacterium aroidearum |
| 125 | 1042298 | 1042585 | + | NZ_LS483470.1 | Leminorella richardii |
| 126 | 4819839 | 4820126 | + | NZ_CP034938.1 | Pectobacterium odoriferum |
| 127 | 380442 | 380729 | + | NZ_CP034938.1 | Pectobacterium odoriferum |
| 128 | 849902 | 850180 | + | NZ_CP035928.1 | Malaciobacter pacificus |
| 129 | 253292 | 253573 | + | NZ_CP017944.1 | Phyllobacterium zundukense |
| 130 | 1500548 | 1500835 | - | NZ_CP017689.1 | Thalassotalea crassostreae |
| 131 | 4107898 | 4108188 | - | NC_020908.1 | Octadecabacter arcticus 238 |
| 132 | 4992802 | 4993092 | - | NC_020908.1 | Octadecabacter arcticus 238 |
| 133 | 271784 | 272074 | + | NC_005126.1 | Photorhabdus laumondii subsp. laumondii TTO1 |
| 134 | 2662395 | 2662682 | - | NC_005126.1 | Photorhabdus laumondii subsp. laumondii TTO1 |
| 135 | 2489450 | 2489740 | + | NC_005126.1 | Photorhabdus laumondii subsp. laumondii TTO1 |
| 136 | 202851 | 203132 | + | NZ_CP061079.1 | Pseudomonas chlororaphis |
| 137 | 93252 | 93539 | + | NZ_CP040428.1 | Jejubacter calystegiae |
| 138 | 3179495 | 3179776 | - | NZ_CP020738.1 | Paraburkholderia acidophila |
| 139 | 1853992 | 1854279 | - | NZ_AP022345.1 | Fluviibacter phosphoraccumulans |
| 140 | 1695378 | 1695668 | + | NC_004757.1 | Nitrosomonas europaea ATCC 19718 |
| 141 | 1714296 | 1714592 | + | NC_004757.1 | Nitrosomonas europaea ATCC 19718 |
| 142 | 1622211 | 1622495 | + | NZ_CP045300.1 | Kosakonia arachidis |
| 143 | 2605905 | 2606189 | - | NZ_CP042652.1 | Pseudoarcobacter acticola |
| 144 | 2482396 | 2482683 | - | NZ_CP065640.1 | Serratia rubidaea |
| 145 | 392090 | 392377 | + | NZ_CP038498.1 | Pectobacterium punjabense |
| 146 | 3830859 | 3831140 | - | NC_021505.1 | Pseudomonas putida NBRC 14164 |
| 147 | 1336265 | 1336549 | - | NC_016629.1 | Desulfocurvibacter africanus subsp. africanus str. Walvis Bay |
| 148 | 3889 | 4173 | - | NZ_CP017756.1 | Cupriavidus malaysiensis |
| 149 | 2257831 | 2258115 | - | NZ_CP032097.1 | Arcobacter ellisii |
| 150 | 977786 | 978070 | - | NC_020304.1 | Desulfocapsa sulfexigens DSM 10523 |
| 151 | 3104031 | 3104321 | + | NZ_CP049134.1 | Paraburkholderia tropica |
| 152 | 543908 | 544192 | - | NZ_CP029206.1 | Actinobacillus porcitonsillarum |
| 153 | 1939383 | 1939664 | + | NC_012779.2 | Edwardsiella ictaluri 93-146 |
| 154 | 3661904 | 3662185 | - | NZ_CP006664.1 | Edwardsiella anguillarum ET080813 |
| 155 | 613435 | 613731 | - | NZ_CP021425.1 | Oleiphilus messinensis |
| 156 | 502455 | 502739 | - | NZ_CP060401.1 | Xenorhabdus nematophila |
| 157 | 4760347 | 4760634 | + | NZ_CP011104.1 | Photorhabdus thracensis |
| 158 | 2396190 | 2396480 | + | NZ_CP019948.1 | Methylocystis bryophila |
| 159 | 3024315 | 3024605 | + | NZ_CP046909.1 | Paraburkholderia acidiphila |
| 160 | 1751761 | 1752042 | - | NZ_CP016043.1 | Edwardsiella hoshinae |
| 161 | 3420993 | 3421274 | - | NZ_CP023706.1 | Edwardsiella tarda |
| 162 | 2848659 | 2848940 | - | NZ_CP013416.1 | Burkholderia ubonensis |
| 163 | 521098 | 521388 | + | NZ_CP007201.1 | Sulfurospirillum multivorans DSM 12446 |
| 164 | 1104284 | 1104565 | + | NZ_CP028339.1 | Thauera aromatica K172 |
| 165 | 4450397 | 4450684 | - | NZ_CP027723.1 | Pseudomonas orientalis |
| 166 | 763830 | 764117 | - | NZ_LS483250.1 | Moritella yayanosii |
| 167 | 3661034 | 3661315 | - | NZ_CP062252.1 | Pseudomonas allokribbensis |
| 168 | 8582 | 8869 | + | NC_010580.1 | Beijerinckia indica subsp. indica ATCC 9039 |
| 169 | 402193 | 402483 | + | NC_018002.1 | Sulfurospirillum barnesii SES-3 |
| 170 | 30094 | 30378 | + | NC_011852.1 | Glaesserella parasuis SH0165 |
| 171 | 894920 | 895201 | + | NZ_CP045302.1 | Azotobacter salinestris |
| 172 | 4803064 | 4803303 | + | NZ_CP045302.1 | Azotobacter salinestris |
| 173 | 543219 | 543509 | + | NZ_CP017111.1 | Sulfurospirillum halorespirans DSM 13726 |
| 174 | 4506302 | 4506580 | + | NZ_AP014857.1 | Escherichia albertii |
| 175 | 2315170 | 2315454 | + | NZ_CP035088.1 | Pseudomonas viciae |
| 176 | 4002947 | 4003240 | - | NZ_LS483422.1 | Providencia heimbachae |
| 177 | 1481354 | 1481635 | + | NZ_HG938353.1 | Neorhizobium galegae bv. orientalis str. HAMBI 540 |
| 178 | 1193641 | 1193931 | + | NZ_CP023464.1 | Pseudoalteromonas atlantica |
| 179 | 2754962 | 2755243 | + | NZ_CP011835.1 | Azotobacter chroococcum |
| 180 | 1534455 | 1534742 | - | NZ_CP009787.1 | Yersinia rohdei |
| 181 | 170008 | 170241 | + | NC_007511.1 | Burkholderia lata |
| 182 | 4561468 | 4561749 | - | NC_012560.1 | Azotobacter vinelandii DJ |
| 183 | 619814 | 620104 | - | NZ_CP010802.1 | Desulfuromonas soudanensis |
| 184 | 2040513 | 2040812 | - | NZ_CP041070.1 | Arcobacter anaerophilus |
| 185 | 2739750 | 2740052 | + | NZ_CP014646.1 | Thauera humireducens |
| 186 | 5197568 | 5197849 | - | NZ_CP013232.1 | Collimonas fungivorans |
| 187 | 2590690 | 2590986 | - | NZ_CP040517.1 | Luteithermobacter gelatinilyticus |
| 188 | 2055677 | 2055976 | - | NC_018691.1 | Alcanivorax dieselolei B5 |
| 189 | 1240505 | 1240792 | - | NC_006512.1 | Idiomarina loihiensis L2TR |
| 190 | 672674 | 672973 | - | NC_013851.1 | Allochromatium vinosum DSM 180 |
| 191 | 4175454 | 4175735 | - | NZ_CP012661.1 | Defluviimonas alba |
| 192 | 166089 | 166376 | + | NZ_CP059567.1 | Neisseria shayeganii |
| 193 | 3253365 | 3253598 | + | NZ_CP019240.1 | Rhodoferax antarcticus |
| 194 | 45534 | 45821 | - | NZ_CP023568.1 | Erwinia pyrifoliae |
| 195 | 10857 | 11144 | - | NZ_CP023568.1 | Erwinia pyrifoliae |
| 196 | 2401781 | 2402065 | + | NC_018645.1 | Desulfobacula toluolica Tol2 |
| 197 | 3075317 | 3075601 | + | NC_018645.1 | Desulfobacula toluolica Tol2 |
| 198 | 805153 | 805434 | + | NC_011761.1 | Acidithiobacillus ferrooxidans ATCC 23270 |
| 199 | 1335313 | 1335594 | + | NZ_CP011504.1 | Burkholderia pyrrocinia |
| 200 | 1518925 | 1519212 | - | NZ_CP063164.1 | Sulfurovum indicum |
| 201 | 1347693 | 1347983 | + | NZ_CP012946.1 | Blastochloris viridis |
| 202 | 256349 | 256618 | + | NZ_CP059564.1 | Alysiella filiformis |
| 203 | 2229800 | 2230081 | + | NC_015942.1 | Acidithiobacillus ferrivorans SS3 |
| 204 | 2075545 | 2075826 | - | NZ_CP011568.3 | Pandoraea thiooxydans |
| 205 | 3063841 | 3064125 | + | NC_017857.3 | Methylophaga nitratireducenticrescens |
| 206 | 4695729 | 4696010 | - | NZ_CP065838.1 | Klebsiella quasipneumoniae |
| 207 | 1588453 | 1588731 | - | NC_020528.1 | Sinorhizobium meliloti 2011 |
| 208 | 2383855 | 2384139 | - | NZ_CP012543.1 | Campylobacter rectus |
| 209 | 5957758 | 5958048 | + | NZ_CP013480.3 | Pandoraea norimbergensis |
| 210 | 54320 | 54601 | - | NZ_CP012541.1 | Campylobacter concisus |
| 211 | 928742 | 929029 | + | NZ_CP022605.1 | [Ochrobactrum] quorumnocens |
| 212 | 5154049 | 5154330 | - | NZ_CP013236.1 | Collimonas pratensis |
| 213 | 3677639 | 3677923 | + | NZ_CP067057.1 | Rahnella aceris |
| 214 | 5817908 | 5818210 | - | NZ_CP048833.1 | Pseudomonas multiresinivorans |
| 215 | 40131 | 40418 | - | NZ_LN681226.1 | Legionella hackeliae |
| 216 | 1963987 | 1964244 | - | NZ_CP062804.1 | Cupriavidus basilensis |
| 217 | 23834 | 24115 | + | NZ_AP018688.1 | Vibrio rumoiensis |
| 218 | 31081 | 31347 | + | NZ_CP044485.1 | Acinetobacter schindleri |
| 219 | 52336 | 52629 | - | NZ_CP071768.1 | Acinetobacter towneri |
| 220 | 24951 | 25202 | - | NZ_CP071768.1 | Acinetobacter towneri |
| 221 | 1784444 | 1784725 | - | NC_013959.1 | Sideroxydans lithotrophicus ES-1 |
| 222 | 2274280 | 2274573 | + | NZ_CP071766.1 | Acinetobacter towneri |
| 223 | 3970183 | 3970449 | + | NZ_CP009460.1 | Dickeya fangzhongdai |
| 224 | 4379370 | 4379669 | + | NC_016112.1 | Methylotuvimicrobium alcaliphilum 20Z |
| 225 | 3252809 | 3253102 | + | NZ_CP062147.1 | Komagataeibacter hansenii |
| 226 | 4670747 | 4671046 | + | NZ_CP035467.1 | Methylotuvimicrobium buryatense |
| 227 | 499325 | 499573 | + | NZ_LR134340.1 | Escherichia marmotae |
| 228 | 682499 | 682768 | + | NZ_CP046027.1 | Neisseria brasiliensis |
| 229 | 111617 | 111901 | - | NZ_CP040760.1 | Paracoccus liaowanqingii |
| 230 | 1348358 | 1348645 | - | NC_007969.1 | Psychrobacter cryohalolentis K5 |
| 231 | 1524603 | 1524890 | + | NC_007204.1 | Psychrobacter arcticus 273-4 |
++ More..
| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NZ_CP034150.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF02604.21 | 0.65 | 124 | -10 | same-strand | Antitoxin Phd YefM, type II toxin-antitoxin system |
++ More..