Result : P0ADG0
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Acetolactate synthase isozyme 1 small subunit (EC 2.2.1.6) (Acetohydroxy-acid synthase I small subunit) (AHAS-I) (ALS-I) |
| NCBI Accession ID | AE005174.2 |
| Organism | Escherichia coli O157:H7 |
| Left | 4710260 |
| Right | 4710550 |
| Strand | - |
| Nucleotide Sequence | ATGCAAAACACAACTCATGACAACGTGATTCTGGAACTCACCGTTCGCAACCATCCGGGCGTAATGACCCACGTTTGTGGCCTTTTTGCCCGCCGCGCTTTTAACGTTGAAGGCATTCTTTGTCTGCCGATTCAGGACAGCGACAAAAGCCATATCTGGCTACTGGTCAATGACGACCAGCGTCTGGAGCAGATGATAAGCCAAATCGATAAGCTGGAAGATGTGGTGAAAGTGCAGCGTAATCAGTCCGATCCGACGATGTTTAACAAGATTGCAGTGTTTTTTCAGTAA |
| Sequence | MQNTTHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPIQDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ |
| Source of smORF | Swiss-Prot |
| Function | The ORF matches to the profile of cl09141. Profile Description: ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme. The ACT domain is a structural motif of 70-90 amino acids that functions in the control of metabolism, solute transport and signal transduction. They are thus found in a variety of different proteins in a variety of different arrangements. In mammalian phenylalanine hydroxylase the domain forms no contacts but promotes an allosteric effect despite the apparent lack of ligand binding. |
| Pubmed ID | 11206551 11258796 |
| Domain | CDD:415594 |
| Functional Category | Others |
| Uniprot ID | P0ADG0 |
| ORF Length (Amino Acid) | 96 |
++ More..
| Conservation Analysis |
No. of Species: 128
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 2923207 | 2923497 | + | NZ_CP057657.1 | Escherichia fergusonii |
| 2 | 3850802 | 3851092 | - | NC_000913.3 | Escherichia coli str. K-12 substr. MG1655 |
| 3 | 3829518 | 3829808 | - | NZ_AP014857.1 | Escherichia albertii |
| 4 | 4641402 | 4641692 | - | NC_002695.2 | Escherichia coli O157:H7 str. Sakai |
| 5 | 4103069 | 4103359 | + | NZ_CP061527.1 | Shigella dysenteriae |
| 6 | 24081 | 24371 | + | NZ_LR134340.1 | Escherichia marmotae |
| 7 | 3900338 | 3900628 | + | NC_004337.2 | Shigella flexneri 2a str. 301 |
| 8 | 2446967 | 2447257 | + | NZ_CP044098.1 | Citrobacter portucalensis |
| 9 | 2632592 | 2632882 | - | NZ_CP033744.1 | Citrobacter freundii |
| 10 | 1335522 | 1335812 | - | NZ_LT556085.1 | Citrobacter amalonaticus |
| 11 | 3458184 | 3458474 | + | NZ_CP038469.1 | Citrobacter tructae |
| 12 | 3995635 | 3995925 | - | NC_003197.2 | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |
| 13 | 32860 | 33150 | + | NZ_CP050508.1 | Raoultella terrigena |
| 14 | 421613 | 421903 | - | NZ_CP045205.1 | Citrobacter telavivensis |
| 15 | 10132 | 10422 | - | NC_009792.1 | Citrobacter koseri ATCC BAA-895 |
| 16 | 4301190 | 4301480 | + | NC_013716.1 | Citrobacter rodentium ICC168 |
| 17 | 1812185 | 1812475 | - | NZ_CP053416.1 | Salmonella bongori |
| 18 | 29852 | 30142 | + | NZ_CP045845.1 | Kluyvera intermedia |
| 19 | 26187 | 26477 | + | NZ_CP041247.1 | Raoultella electrica |
| 20 | 1693676 | 1693966 | - | NZ_CP026047.1 | Raoultella planticola |
| 21 | 33040 | 33330 | + | NZ_CP046672.1 | Raoultella ornithinolytica |
| 22 | 4594280 | 4594567 | - | NZ_CP012871.1 | [Enterobacter] lignolyticus |
| 23 | 35248 | 35535 | + | NZ_AP022508.1 | Enterobacter bugandensis |
| 24 | 2416797 | 2417084 | - | NZ_AP019007.1 | Enterobacter oligotrophicus |
| 25 | 36058 | 36345 | + | NC_015968.1 | Enterobacter soli |
| 26 | 20430 | 20720 | + | NZ_CP054058.1 | Scandinavium goeteborgense |
| 27 | 3537987 | 3538274 | - | NZ_CP045769.1 | Enterobacter cancerogenus |
| 28 | 3268272 | 3268559 | + | NZ_CP017279.1 | Enterobacter ludwigii |
| 29 | 94848 | 95138 | - | NZ_CP036175.1 | Klebsiella huaxiensis |
| 30 | 510123 | 510413 | + | NZ_CP051548.1 | Phytobacter diazotrophicus |
| 31 | 4643588 | 4643878 | + | NZ_CP011602.1 | Phytobacter ursingii |
| 32 | 33190 | 33477 | + | NZ_CP027986.1 | Enterobacter sichuanensis |
| 33 | 30590 | 30877 | + | NZ_CP017184.1 | Enterobacter roggenkampii |
| 34 | 2550833 | 2551120 | - | NZ_CP025034.2 | Enterobacter sp. SGAir0187 |
| 35 | 35343 | 35630 | + | NZ_CP043318.1 | Enterobacter chengduensis |
| 36 | 3517865 | 3518152 | + | NZ_CP023529.1 | Lelliottia amnigena |
| 37 | 36829 | 37116 | + | NZ_CP009756.1 | Enterobacter cloacae |
| 38 | 85124 | 85414 | + | NZ_CP060111.1 | Klebsiella michiganensis |
| 39 | 4741283 | 4741570 | - | NZ_CP013990.1 | Leclercia adecarboxylata |
| 40 | 33856 | 34143 | + | NZ_LR134475.1 | Klebsiella aerogenes |
| 41 | 28870 | 29157 | + | NZ_CP065838.1 | Klebsiella quasipneumoniae |
| 42 | 5264429 | 5264716 | - | NC_016845.1 | Klebsiella pneumoniae subsp. pneumoniae HS11286 |
| 43 | 28947 | 29234 | + | NZ_CP054254.1 | Klebsiella variicola |
| 44 | 931876 | 932166 | + | NZ_CP020388.1 | Pluralibacter gergoviae |
| 45 | 26274 | 26558 | + | NZ_CP035129.1 | Kosakonia cowanii |
| 46 | 5287363 | 5287611 | - | NZ_CP015113.1 | Kosakonia radicincitans |
| 47 | 3072644 | 3072892 | - | NZ_CP016337.1 | Kosakonia sacchari |
| 48 | 4830587 | 4830835 | - | NZ_CP063425.1 | Kosakonia pseudosacchari |
| 49 | 3189439 | 3189687 | - | NZ_CP045300.1 | Kosakonia arachidis |
| 50 | 26556 | 26804 | + | NZ_CP014007.2 | Kosakonia oryzae |
| 51 | 1756559 | 1756840 | + | NZ_CP042941.1 | Atlantibacter hermannii |
| 52 | 3760504 | 3760752 | - | NZ_CP023525.1 | Cedecea neteri |
| 53 | 3416096 | 3416344 | - | NZ_LR134201.1 | Cedecea lapagei |
| 54 | 56961 | 57209 | - | NZ_CP016948.1 | Serratia surfactantfaciens |
| 55 | 733602 | 733850 | - | NZ_CP038662.1 | Serratia nematodiphila |
| 56 | 1905819 | 1906067 | + | NZ_CP014136.1 | Gibbsiella quercinecans |
| 57 | 4332015 | 4332263 | + | NZ_CP071320.1 | Serratia ureilytica |
| 58 | 724936 | 725202 | - | NZ_LR134494.1 | Serratia quinivorans |
| 59 | 663742 | 664035 | - | NZ_CP042220.2 | Dickeya poaceiphila |
| 60 | 814897 | 815163 | - | NZ_LT906479.1 | Serratia ficaria |
| 61 | 688504 | 688770 | - | NZ_CP048784.1 | Serratia liquefaciens |
| 62 | 2259608 | 2259901 | - | NZ_CP065640.1 | Serratia rubidaea |
| 63 | 4201882 | 4202130 | + | NZ_CP034938.1 | Pectobacterium odoriferum |
| 64 | 3319386 | 3319634 | - | NZ_AP023184.1 | Buttiauxella agrestis |
| 65 | 747409 | 747675 | - | NC_015567.1 | Serratia plymuthica AS9 |
| 66 | 3007060 | 3007308 | + | NZ_CP017482.1 | Pectobacterium polaris |
| 67 | 4933903 | 4934151 | - | NZ_CP015749.1 | Pectobacterium parmentieri |
| 68 | 2348608 | 2348856 | - | NZ_CP047495.1 | Pectobacterium brasiliense |
| 69 | 922144 | 922437 | + | NZ_CP015750.1 | Pectobacterium wasabiae CFBP 3304 |
| 70 | 678712 | 678960 | - | NZ_CP051652.1 | Pectobacterium carotovorum |
| 71 | 4175047 | 4175340 | + | NZ_CP009125.1 | Pectobacterium atrosepticum |
| 72 | 698859 | 699155 | - | NC_012880.1 | Musicola paradisiaca Ech703 |
| 73 | 3854796 | 3855089 | + | NZ_LT615367.1 | Dickeya aquatica |
| 74 | 4008472 | 4008720 | + | NZ_CP038498.1 | Pectobacterium punjabense |
| 75 | 744779 | 745045 | - | NZ_CP034036.1 | Brenneria nigrifluens DSM 30175 = ATCC 13028 |
| 76 | 5178939 | 5179187 | - | NZ_CP014137.1 | Brenneria goodwinii |
| 77 | 823135 | 823383 | - | NZ_CP065044.1 | Pectobacterium aroidearum |
| 78 | 660787 | 661080 | - | NC_012912.1 | Dickeya chrysanthemi Ech1591 |
| 79 | 542576 | 542869 | + | NZ_CP023009.1 | Lonsdalea britannica |
| 80 | 3162751 | 3162999 | + | NZ_CP034035.1 | Brenneria rubrifaciens |
| 81 | 5209375 | 5209623 | + | NZ_CP007044.2 | Chania multitudinisentens RB-25 |
| 82 | 2678705 | 2678971 | - | NZ_CP011254.1 | Serratia fonticola |
| 83 | 3983441 | 3983734 | + | NZ_CP025799.1 | Dickeya zeae |
| 84 | 487268 | 487561 | - | NZ_CP065534.1 | Lonsdalea populi |
| 85 | 4167153 | 4167446 | + | NZ_CP031560.1 | Dickeya dianthicola |
| 86 | 4150930 | 4151223 | + | NC_014500.1 | Dickeya dadantii 3937 |
| 87 | 3580596 | 3580889 | - | NZ_CP009460.1 | Dickeya fangzhongdai |
| 88 | 2142705 | 2142995 | - | NZ_CP029331.1 | Thauera hydrothermalis |
| 89 | 1330062 | 1330355 | + | NZ_CP015137.1 | Dickeya solani IPO 2222 |
| 90 | 144591 | 144839 | + | NZ_CP014646.1 | Thauera humireducens |
| 91 | 1195302 | 1195550 | + | NZ_CP016210.1 | Azoarcus olearius |
| 92 | 3630531 | 3630779 | - | NZ_CP018839.1 | Thauera chlorobenzoica |
| 93 | 1237146 | 1237394 | + | NZ_CP028339.1 | Thauera aromatica K172 |
| 94 | 416805 | 417062 | - | NZ_CP009781.1 | Yersinia aldovae 670-83 |
| 95 | 1892620 | 1892865 | - | NZ_LS483470.1 | Leminorella richardii |
| 96 | 1808156 | 1808395 | - | NZ_CP032487.1 | Yersinia hibernica |
| 97 | 2811805 | 2812095 | + | NC_006513.1 | Aromatoleum aromaticum EbN1 |
| 98 | 762915 | 763205 | - | NZ_CP059467.1 | Aromatoleum bremense |
| 99 | 2289053 | 2289310 | - | NZ_CP043727.1 | Yersinia canariae |
| 100 | 2094600 | 2094884 | + | NZ_LR134531.1 | Pragia fontium |
| 101 | 441517 | 441765 | + | NC_016803.1 | Pseudodesulfovibrio mercurii |
| 102 | 4000928 | 4001218 | + | NZ_CP059560.1 | Aromatoleum petrolei |
| 103 | 2317848 | 2318084 | + | NZ_CP046293.1 | Yersinia intermedia |
| 104 | 4455542 | 4455826 | + | NZ_CP031123.2 | Providencia huaxiensis |
| 105 | 3840428 | 3840712 | + | NC_010554.1 | Proteus mirabilis HI4320 |
| 106 | 1784654 | 1784947 | - | NZ_CP034752.1 | Jinshanibacter zhutongyuii |
| 107 | 635349 | 635633 | + | NZ_LS483422.1 | Providencia heimbachae |
| 108 | 2361138 | 2361404 | + | NZ_CP011118.1 | Yersinia enterocolitica |
| 109 | 1952634 | 1952918 | + | NZ_CP026364.1 | Proteus hauseri |
| 110 | 1881020 | 1881268 | - | NC_014844.1 | Pseudodesulfovibrio aespoeensis Aspo-2 |
| 111 | 248147 | 248431 | - | NZ_CP029736.1 | Providencia rettgeri |
| 112 | 1789970 | 1790263 | - | NZ_CP029185.2 | Limnobaculum parvum |
| 113 | 583519 | 583803 | + | NZ_CP048796.1 | Providencia vermicola |
| 114 | 356733 | 357017 | + | NZ_CP047349.1 | Proteus terrae subsp. cibarius |
| 115 | 4205736 | 4205972 | + | NZ_CP007230.1 | Yersinia similis |
| 116 | 674873 | 675109 | + | NZ_CP009787.1 | Yersinia rohdei |
| 117 | 3229941 | 3230189 | - | NZ_CP046400.1 | Pseudodesulfovibrio cashew |
| 118 | 2046580 | 2046816 | - | NZ_LR134373.1 | Yersinia pseudotuberculosis |
| 119 | 672632 | 672877 | - | NZ_LT907975.1 | Pseudodesulfovibrio profundus |
| 120 | 415724 | 415975 | + | NC_017310.1 | Desulfovibrio vulgaris RCH1 |
| 121 | 3538107 | 3538373 | - | NZ_CP064781.1 | Azospira restricta |
| 122 | 1303831 | 1304091 | - | NZ_AP018558.1 | Hydrogenophilus thermoluteolus |
| 123 | 574246 | 574497 | - | NZ_AP017378.1 | Desulfovibrio ferrophilus |
| 124 | 1845455 | 1845712 | - | NC_013173.1 | Desulfomicrobium baculatum DSM 4028 |
| 125 | 1127583 | 1127849 | + | NZ_CP022579.1 | Oryzomicrobium terrae |
| 126 | 2972145 | 2972393 | + | NZ_CP043998.1 | Clostridium diolis |
| 127 | 2219971 | 2220207 | + | NZ_CP030775.1 | Clostridium butyricum |
| 128 | 1925875 | 1926111 | - | NC_022571.1 | Clostridium saccharobutylicum DSM 13864 |
| 129 | 3479907 | 3480161 | - | NC_020291.1 | Clostridium saccharoperbutylacetonicum N1-4(HMT) |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NZ_CP057657.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF02776.20 | 1.0 | 128 | 4 | same-strand | Thiamine pyrophosphate enzyme, N-terminal TPP binding domain |
| 2 | PF02775.23 | 1.0 | 128 | 4 | same-strand | Thiamine pyrophosphate enzyme, C-terminal TPP binding domain |
| 3 | PF00205.24 | 1.0 | 128 | 4 | same-strand | Thiamine pyrophosphate enzyme, central domain |
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