Result : P0AD91
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Tryptophanase operon leader peptide |
| NCBI Accession ID | AE005174.2 |
| Organism | Escherichia coli O157:H7 |
| Left | 4746125 |
| Right | 4746199 |
| Strand | + |
| Nucleotide Sequence | ATGAATATCTTACATATATGTGTGACCTCAAAATGGTTCAATATTGACAACAAGATTGTCGATCACCGCCCTTGA |
| Sequence | MNILHICVTSKWFNIDNKIVDHRP |
| Source of smORF | Swiss-Prot |
| Function | The ORF matches to the profile of TIGR02616. Profile Description: tryptophanase leader peptide. Members of this family are the apparent leader peptides of tryptophanase operons in Esherichia coli, Vibrio cholerae, Photobacterium profundum, Haemophilus influenzae type b, and related species. All members of the seed alignment are examples ORFs upstream of tryptophanase, with a start codon, a conserved single Trp residue, and several other conserved residues. It is suggested (Konan KV and Yanofsky C) that the nascent peptide interacts with the ribosome once (if) the ribosome reaches the stop codon. Note that this model describes a much broader set (and shorter protein region) than pfam08053. [Energy metabolism, Amino acids and amines, Transcription, Other] |
| Pubmed ID | 11206551 11258796 |
| Domain | CDD:274233 |
| Functional Category | Others |
| Uniprot ID | P0AD91 |
| ORF Length (Amino Acid) | 24 |
++ More..
| Conservation Analysis |
No. of Species: 11
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 4677269 | 4677343 | + | NC_002695.2 | Escherichia coli O157:H7 str. Sakai |
| 2 | 3863018 | 3863092 | + | NZ_AP014857.1 | Escherichia albertii |
| 3 | 3888435 | 3888509 | + | NC_000913.3 | Escherichia coli str. K-12 substr. MG1655 |
| 4 | 2885440 | 2885514 | - | NZ_CP057657.1 | Escherichia fergusonii |
| 5 | 2679880 | 2679954 | - | NZ_CP019706.1 | Pantoea alhagi |
| 6 | 3863473 | 3863547 | - | NC_004337.2 | Shigella flexneri 2a str. 301 |
| 7 | 4445211 | 4445285 | - | NZ_LR134340.1 | Escherichia marmotae |
| 8 | 1218411 | 1218485 | - | NZ_LT556085.1 | Citrobacter amalonaticus |
| 9 | 4774749 | 4774823 | + | NZ_CP013990.1 | Leclercia adecarboxylata |
| 10 | 3424099 | 3424173 | - | NZ_CP038469.1 | Citrobacter tructae |
| 11 | 2231933 | 2232004 | + | NZ_CP012871.1 | [Enterobacter] lignolyticus |
| 12 | 461177 | 461251 | + | NZ_CP045205.1 | Citrobacter telavivensis |
++ More..
| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NZ_AP014857.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF00825.20 | 0.73 | 8 | 3583 | same-strand | Ribonuclease P |
| 2 | PF14849.8 | 0.73 | 8 | 1713 | same-strand | YidC periplasmic domain |
| 3 | PF02096.22 | 0.73 | 8 | 1713 | same-strand | 60Kd inner membrane protein |
| 4 | PF12631.9 | 0.73 | 8 | 243 | same-strand | MnmE helical domain |
| 5 | PF10396.11 | 0.73 | 8 | 243 | same-strand | GTP-binding protein TrmE N-terminus |
| 6 | PF01926.25 | 0.64 | 7 | 243.0 | same-strand | 50S ribosome-binding GTPase |
| 7 | PF01212.23 | 1.0 | 11 | 224.5 | same-strand | Beta-eliminating lyase |
| 8 | PF03222.15 | 0.91 | 10 | 1730 | same-strand | Tryptophan/tyrosine permease family |
| 9 | PF07690.18 | 0.64 | 7 | 3107.0 | same-strand | Major Facilitator Superfamily |
| 10 | PF03466.22 | 0.64 | 7 | 4257.0 | same-strand | LysR substrate binding domain |
| 11 | PF00126.29 | 0.73 | 8 | 4256 | same-strand | Bacterial regulatory helix-turn-helix protein, lysR family |
| 12 | PF11638.10 | 0.64 | 7 | 4706 | opposite-strand | DnaA N-terminal domain |
++ More..