Result : P0ABT1
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | DNA polymerase III subunit theta (EC 2.7.7.7) |
| NCBI Accession ID | AE005674.2 |
| Organism | Shigella flexneri |
| Left | 1888980 |
| Right | 1889210 |
| Strand | + |
| Nucleotide Sequence | ATGCTGAAGAATCTGGCTAAACTGGATCAAACAGAAATGGATAAAGTGAATGTCGATTTGGCGGCGGCCGGGGTGGCTTTTAAAGAACGCTACAATATGCCGGTGATCGCTGAAGCGGTTGAACGTGAACAGCCAGAACATTTGCGCAGCTGGTTTCGCGAGCGGCTTATTGCCCACCGTTTGGCTTCGGTCAATCTGTCACGTTTACCTTACGAGCCCAAACTTAAATAA |
| Sequence | MLKNLAKLDQTEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQPEHLRSWFRERLIAHRLASVNLSRLPYEPKLK |
| Source of smORF | Swiss-Prot |
| Function | DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity). {ECO:0000250}.; The exact function of the theta subunit is unknown. {ECO:0000250}. |
| Pubmed ID | 12384590 12704152 |
| Domain | CDD:419852 |
| Functional Category | Others |
| Uniprot ID | P0ABT1 |
| ORF Length (Amino Acid) | 76 |
++ More..
| Conservation Analysis |
No. of Species: 144
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 2496760 | 2496990 | + | NZ_CP061527.1 | Shigella dysenteriae |
| 2 | 1888980 | 1889210 | + | NC_004337.2 | Shigella flexneri 2a str. 301 |
| 3 | 1925108 | 1925338 | + | NC_000913.3 | Escherichia coli str. K-12 substr. MG1655 |
| 4 | 2527076 | 2527306 | + | NC_002695.2 | Escherichia coli O157:H7 str. Sakai |
| 5 | 1924775 | 1925005 | - | NZ_LR134340.1 | Escherichia marmotae |
| 6 | 1866311 | 1866541 | + | NZ_AP014857.1 | Escherichia albertii |
| 7 | 2000864 | 2001094 | + | NC_013716.1 | Citrobacter rodentium ICC168 |
| 8 | 220950 | 221135 | - | NZ_CP057657.1 | Escherichia fergusonii |
| 9 | 4469556 | 4469786 | + | NZ_CP053416.1 | Salmonella bongori |
| 10 | 197580 | 197810 | - | NZ_CP016337.1 | Kosakonia sacchari |
| 11 | 2871329 | 2871559 | + | NZ_CP063425.1 | Kosakonia pseudosacchari |
| 12 | 95575 | 95805 | - | NZ_CP045300.1 | Kosakonia arachidis |
| 13 | 2194825 | 2195055 | - | NZ_CP014007.2 | Kosakonia oryzae |
| 14 | 3009758 | 3009988 | + | NZ_CP015113.1 | Kosakonia radicincitans |
| 15 | 1949794 | 1949979 | - | NZ_CP035129.1 | Kosakonia cowanii |
| 16 | 1970051 | 1970281 | + | NC_003197.2 | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |
| 17 | 2530619 | 2530849 | + | NZ_CP012264.1 | Cronobacter condimenti 1330 |
| 18 | 1426505 | 1426699 | + | NZ_CP038469.1 | Citrobacter tructae |
| 19 | 4504442 | 4504636 | - | NZ_CP044098.1 | Citrobacter portucalensis |
| 20 | 634080 | 634274 | + | NZ_CP033744.1 | Citrobacter freundii |
| 21 | 877806 | 878036 | - | NZ_CP027107.1 | Cronobacter sakazakii |
| 22 | 1612710 | 1612940 | - | NZ_CP013940.1 | Cronobacter malonaticus LMG 23826 |
| 23 | 2571472 | 2571702 | + | NZ_CP012257.1 | Cronobacter universalis NCTC 9529 |
| 24 | 2561500 | 2561730 | + | NZ_CP011602.1 | Phytobacter ursingii |
| 25 | 2794721 | 2794951 | + | NZ_AP022508.1 | Enterobacter bugandensis |
| 26 | 1806442 | 1806672 | - | NZ_LR134201.1 | Cedecea lapagei |
| 27 | 1447015 | 1447245 | - | NZ_CP012268.1 | Cronobacter muytjensii ATCC 51329 |
| 28 | 2668500 | 2668730 | + | NZ_CP012266.1 | Cronobacter dublinensis subsp. dublinensis LMG 23823 |
| 29 | 2228282 | 2228512 | - | NZ_CP060111.1 | Klebsiella michiganensis |
| 30 | 1875127 | 1875357 | - | NZ_CP045845.1 | Kluyvera intermedia |
| 31 | 1096814 | 1097044 | - | NC_009792.1 | Citrobacter koseri ATCC BAA-895 |
| 32 | 4334819 | 4335049 | + | NZ_CP040428.1 | Jejubacter calystegiae |
| 33 | 2772252 | 2772482 | - | NZ_CP045205.1 | Citrobacter telavivensis |
| 34 | 2699192 | 2699422 | + | NZ_CP012871.1 | [Enterobacter] lignolyticus |
| 35 | 4170309 | 4170539 | + | NZ_LT556085.1 | Citrobacter amalonaticus |
| 36 | 1779739 | 1779969 | - | NZ_CP054058.1 | Scandinavium goeteborgense |
| 37 | 2451099 | 2451353 | - | NZ_CP054058.1 | Scandinavium goeteborgense |
| 38 | 1896563 | 1896793 | - | NZ_AP023184.1 | Buttiauxella agrestis |
| 39 | 4473737 | 4473922 | - | NZ_CP025034.2 | Enterobacter sp. SGAir0187 |
| 40 | 1972088 | 1972318 | - | NZ_CP041247.1 | Raoultella electrica |
| 41 | 5230674 | 5230904 | + | NZ_CP026047.1 | Raoultella planticola |
| 42 | 2046590 | 2046820 | - | NZ_CP046672.1 | Raoultella ornithinolytica |
| 43 | 673639 | 673869 | - | NZ_CP045769.1 | Enterobacter cancerogenus |
| 44 | 2818166 | 2818351 | + | NZ_CP017184.1 | Enterobacter roggenkampii |
| 45 | 2747621 | 2747806 | + | NC_015968.1 | Enterobacter soli |
| 46 | 2905307 | 2905492 | + | NZ_CP009756.1 | Enterobacter cloacae |
| 47 | 3013977 | 3014162 | + | NZ_CP043318.1 | Enterobacter chengduensis |
| 48 | 2816071 | 2816256 | + | NZ_CP027986.1 | Enterobacter sichuanensis |
| 49 | 2038733 | 2038918 | + | NZ_CP017279.1 | Enterobacter ludwigii |
| 50 | 2319016 | 2319246 | - | NZ_CP036175.1 | Klebsiella huaxiensis |
| 51 | 1988244 | 1988474 | - | NZ_LR134475.1 | Klebsiella aerogenes |
| 52 | 621569 | 621754 | + | NZ_AP019007.1 | Enterobacter oligotrophicus |
| 53 | 2086867 | 2087097 | - | NZ_CP050508.1 | Raoultella terrigena |
| 54 | 1929986 | 1930216 | - | NZ_CP054254.1 | Klebsiella variicola |
| 55 | 4076872 | 4077066 | + | NZ_CP020388.1 | Pluralibacter gergoviae |
| 56 | 3787855 | 3788085 | + | NZ_CP051548.1 | Phytobacter diazotrophicus |
| 57 | 1564102 | 1564296 | + | NZ_CP023529.1 | Lelliottia amnigena |
| 58 | 1880489 | 1880719 | - | NZ_CP023525.1 | Cedecea neteri |
| 59 | 3522432 | 3522662 | - | NZ_CP042941.1 | Atlantibacter hermannii |
| 60 | 1861965 | 1862195 | - | NZ_CP065838.1 | Klebsiella quasipneumoniae |
| 61 | 3355210 | 3355440 | + | NC_016845.1 | Klebsiella pneumoniae subsp. pneumoniae HS11286 |
| 62 | 1863421 | 1863651 | - | NZ_CP013990.1 | Leclercia adecarboxylata |
| 63 | 2358222 | 2358407 | + | NC_017910.1 | Shimwellia blattae DSM 4481 = NBRC 105725 |
| 64 | 2594336 | 2594563 | + | NZ_CP026377.1 | Mixta gaviniae |
| 65 | 3238147 | 3238389 | + | NZ_CP026377.1 | Mixta gaviniae |
| 66 | 2800045 | 2800275 | + | NC_014306.1 | Erwinia billingiae Eb661 |
| 67 | 3408535 | 3408762 | - | NZ_CP019706.1 | Pantoea alhagi |
| 68 | 3247337 | 3247582 | - | NZ_CP019706.1 | Pantoea alhagi |
| 69 | 2462838 | 2463065 | + | NZ_CP061511.1 | Mixta calida |
| 70 | 1031342 | 1031584 | - | NZ_CP061511.1 | Mixta calida |
| 71 | 1704467 | 1704697 | + | NZ_CP028271.1 | Mixta intestinalis |
| 72 | 1713200 | 1713430 | - | NC_010694.1 | Erwinia tasmaniensis Et1/99 |
| 73 | 2186205 | 2186435 | + | NZ_CP023567.1 | Erwinia pyrifoliae |
| 74 | 1787973 | 1788206 | - | NZ_CP045720.1 | Pantoea eucalypti |
| 75 | 2097131 | 2097361 | + | NC_013961.1 | Erwinia amylovora CFBP1430 |
| 76 | 983993 | 984223 | - | NZ_CP017482.1 | Pectobacterium polaris |
| 77 | 2242704 | 2242934 | - | NZ_CP065044.1 | Pectobacterium aroidearum |
| 78 | 724474 | 724704 | + | NZ_CP049115.1 | Pantoea stewartii |
| 79 | 2290807 | 2291040 | + | NZ_CP034148.1 | Pantoea agglomerans |
| 80 | 2075327 | 2075557 | - | NC_017554.1 | Pantoea ananatis PA13 |
| 81 | 1980272 | 1980514 | - | NC_017554.1 | Pantoea ananatis PA13 |
| 82 | 4134439 | 4134681 | + | NC_017554.1 | Pantoea ananatis PA13 |
| 83 | 1778980 | 1779213 | - | NZ_CP038853.1 | Pantoea vagans |
| 84 | 1843360 | 1843590 | + | NZ_CP015749.1 | Pectobacterium parmentieri |
| 85 | 1988069 | 1988299 | + | NZ_CP014137.1 | Brenneria goodwinii |
| 86 | 3929365 | 3929595 | - | NZ_CP015750.1 | Pectobacterium wasabiae CFBP 3304 |
| 87 | 4351715 | 4351909 | + | NZ_CP065640.1 | Serratia rubidaea |
| 88 | 2239706 | 2239936 | + | NZ_LN907827.1 | Erwinia gerundensis |
| 89 | 2073974 | 2074204 | + | NZ_CP034035.1 | Brenneria rubrifaciens |
| 90 | 2173761 | 2173991 | - | NZ_CP038498.1 | Pectobacterium punjabense |
| 91 | 3770547 | 3770777 | - | NZ_CP047495.1 | Pectobacterium brasiliense |
| 92 | 2612410 | 2612640 | + | NZ_CP051652.1 | Pectobacterium carotovorum |
| 93 | 2750386 | 2750616 | + | NZ_CP034938.1 | Pectobacterium odoriferum |
| 94 | 2646707 | 2646937 | + | NZ_CP034036.1 | Brenneria nigrifluens DSM 30175 = ATCC 13028 |
| 95 | 2291879 | 2292109 | - | NZ_CP009125.1 | Pectobacterium atrosepticum |
| 96 | 5067697 | 5067927 | - | NZ_CP014136.1 | Gibbsiella quercinecans |
| 97 | 5259038 | 5259268 | + | NZ_CP011254.1 | Serratia fonticola |
| 98 | 2069345 | 2069530 | - | NZ_LR134494.1 | Serratia quinivorans |
| 99 | 2097149 | 2097379 | - | NZ_LT906479.1 | Serratia ficaria |
| 100 | 4056108 | 4056338 | + | NZ_CP007044.2 | Chania multitudinisentens RB-25 |
| 101 | 2956365 | 2956595 | - | NZ_CP023536.1 | Providencia alcalifaciens |
| 102 | 2013534 | 2013719 | - | NZ_CP048784.1 | Serratia liquefaciens |
| 103 | 2153642 | 2153872 | - | NZ_CP048796.1 | Providencia vermicola |
| 104 | 2044191 | 2044376 | - | NC_015567.1 | Serratia plymuthica AS9 |
| 105 | 2976018 | 2976248 | + | NZ_CP029736.1 | Providencia rettgeri |
| 106 | 1715194 | 1715424 | + | NZ_CP031123.2 | Providencia huaxiensis |
| 107 | 2078776 | 2079006 | - | NZ_LS483422.1 | Providencia heimbachae |
| 108 | 2026502 | 2026687 | - | NZ_CP038662.1 | Serratia nematodiphila |
| 109 | 2529054 | 2529284 | + | NC_013892.1 | Xenorhabdus bovienii SS-2004 |
| 110 | 1908530 | 1908760 | + | NZ_CP067057.1 | Rahnella aceris |
| 111 | 3030581 | 3030766 | + | NZ_CP071320.1 | Serratia ureilytica |
| 112 | 1341497 | 1341682 | - | NZ_CP016948.1 | Serratia surfactantfaciens |
| 113 | 1729718 | 1729948 | - | NZ_FO704550.1 | Xenorhabdus doucetiae |
| 114 | 3192769 | 3192999 | + | NC_005126.1 | Photorhabdus laumondii subsp. laumondii TTO1 |
| 115 | 2460748 | 2460972 | + | NZ_CP050150.1 | Hafnia alvei |
| 116 | 649622 | 649852 | + | NZ_CP011078.1 | Yersinia ruckeri |
| 117 | 3842616 | 3842849 | + | NZ_CP026364.1 | Proteus hauseri |
| 118 | 1946565 | 1946792 | - | NZ_CP006569.1 | Sodalis praecaptivus |
| 119 | 1945303 | 1945533 | - | NZ_CP072455.1 | Xenorhabdus budapestensis |
| 120 | 4150747 | 4150977 | - | NZ_CP011104.1 | Photorhabdus thracensis |
| 121 | 2077171 | 2077401 | - | NC_012962.1 | Photorhabdus asymbiotica |
| 122 | 1465913 | 1466143 | + | NZ_CP016176.1 | Xenorhabdus hominickii |
| 123 | 2252721 | 2252954 | + | NZ_CP015581.1 | Tatumella citrea |
| 124 | 1477575 | 1477805 | - | NZ_FO704551.1 | Xenorhabdus poinarii G6 |
| 125 | 2546753 | 2546983 | + | NZ_CP046293.1 | Yersinia intermedia |
| 126 | 236382 | 236615 | + | NZ_CP046293.1 | Yersinia intermedia |
| 127 | 943143 | 943370 | - | NZ_CP046293.1 | Yersinia intermedia |
| 128 | 3238291 | 3238521 | - | NZ_CP054043.1 | Yersinia mollaretii ATCC 43969 |
| 129 | 2111667 | 2111894 | + | NZ_CP016043.1 | Edwardsiella hoshinae |
| 130 | 2050384 | 2050617 | - | NZ_CP043727.1 | Yersinia canariae |
| 131 | 1713879 | 1714103 | + | NC_010554.1 | Proteus mirabilis HI4320 |
| 132 | 1978736 | 1978966 | + | NZ_CP060401.1 | Xenorhabdus nematophila |
| 133 | 2569391 | 2569621 | + | NZ_LR134373.1 | Yersinia pseudotuberculosis |
| 134 | 2279711 | 2279944 | + | NZ_CP047349.1 | Proteus terrae subsp. cibarius |
| 135 | 3237439 | 3237669 | + | NZ_CP023009.1 | Lonsdalea britannica |
| 136 | 2029029 | 2029262 | - | NZ_CP011118.1 | Yersinia enterocolitica |
| 137 | 1993033 | 1993263 | + | NZ_CP065534.1 | Lonsdalea populi |
| 138 | 3674128 | 3674358 | - | NZ_CP007230.1 | Yersinia similis |
| 139 | 162804 | 163031 | + | NZ_CP023706.1 | Edwardsiella tarda |
| 140 | 2291810 | 2292040 | - | NC_014500.1 | Dickeya dadantii 3937 |
| 141 | 2565078 | 2565308 | + | NC_012912.1 | Dickeya chrysanthemi Ech1591 |
| 142 | 2250452 | 2250682 | - | NZ_CP031560.1 | Dickeya dianthicola |
| 143 | 4444298 | 4444528 | - | NZ_CP015137.1 | Dickeya solani IPO 2222 |
| 144 | 2511145 | 2511375 | + | NC_012880.1 | Musicola paradisiaca Ech703 |
| 145 | 1658454 | 1658681 | - | NC_012779.2 | Edwardsiella ictaluri 93-146 |
| 146 | 1506167 | 1506355 | - | NZ_CP032487.1 | Yersinia hibernica |
| 147 | 912441 | 912671 | + | NZ_CP009787.1 | Yersinia rohdei |
| 148 | 474423 | 474653 | + | NZ_CP009460.1 | Dickeya fangzhongdai |
| 149 | 2321106 | 2321339 | + | NZ_LT615367.1 | Dickeya aquatica |
| 150 | 3565702 | 3565929 | - | NZ_CP006664.1 | Edwardsiella anguillarum ET080813 |
| 151 | 2259695 | 2259925 | + | NZ_CP042220.2 | Dickeya poaceiphila |
| 152 | 2237943 | 2238173 | - | NZ_CP025799.1 | Dickeya zeae |
| 153 | 828513 | 828698 | + | NZ_CP009781.1 | Yersinia aldovae 670-83 |
| 154 | 30192 | 30437 | - | NZ_CP026049.1 | Raoultella planticola |
| 155 | 106210 | 106455 | - | NZ_CP036176.1 | Klebsiella huaxiensis |
| 156 | 87023 | 87274 | - | NZ_CP049117.1 | Pantoea stewartii |
| 157 | 5611 | 5865 | - | NZ_CP026048.1 | Raoultella planticola |
| 158 | 136737 | 136991 | - | NZ_CP065839.1 | Klebsiella quasipneumoniae |
| 159 | 97295 | 97549 | - | NZ_CP054255.1 | Klebsiella variicola |
| 160 | 72852 | 73106 | - | NZ_CP041250.1 | Raoultella electrica |
| 161 | 96376 | 96630 | - | NC_016846.1 | Klebsiella pneumoniae subsp. pneumoniae HS11286 |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NZ_CP061527.1
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF10709.11 | 0.9 | 129 | 1426.5 | opposite-strand | Protein of unknown function (DUF2511) |
| 2 | PF05425.15 | 0.82 | 118 | 546 | opposite-strand | Copper resistance protein D |
| 3 | PF04234.14 | 0.81 | 116 | 162 | opposite-strand | CopC domain |
| 4 | PF00929.26 | 0.64 | 92 | 782 | same-strand | Exonuclease |
| 5 | PF02897.17 | 0.81 | 116 | 808 | opposite-strand | Prolyl oligopeptidase, N-terminal beta-propeller domain |
| 6 | PF00326.23 | 0.79 | 114 | 808 | opposite-strand | Prolyl oligopeptidase family |
++ More..