ProsmORF-pred
Result : P05834
Protein Information
Information Type Description
Protein name Bacteriocin microcin B17 (MccB17)
NCBI Accession ID
Organism Escherichia coli
Left
Right
Strand
Nucleotide Sequence
Sequence MELKASEFGVVLSVDALKLSRQSPLGVGIGGGGGGGGGGSCGGQGGGCGGCSNGCSGGNGGSGGSGSHI
Source of smORF Swiss-Prot
Function This glycine-rich peptide antibiotic inhibits DNA replication in many enteric bacteria, that leads to induction of the SOS repair system, massive DNA degradation and cell death. B17 inhibits type II topoisomerase by trapping an enzyme - DNA cleavable complex. {ECO:0000269|Pubmed:1846808}.
Pubmed ID 3329729 2644225 2835580 8183941 1846808 9545435
Domain
Functional Category Antimicrobial
Uniprot ID P05834
ORF Length (Amino Acid) 69
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