Result : A0A140ND86
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Antitoxin DinJ |
| NCBI Accession ID | CP001665.1 |
| Organism | Escherichia coli (strain B / BL21-DE3) |
| Left | 3531308 |
| Right | 3531568 |
| Strand | + |
| Nucleotide Sequence | ATGGCTGCTAACGCGTTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGGGCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAAGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGCCTAATCAATTAACCATTCAATCAATTAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTATTTGATAAATTAGGAATTTAA |
| Sequence | MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVAREKALPFDLREPNQLTIQSIKNSEAGVDVHKAKDADDLFDKLGI |
| Source of smORF | Swiss-Prot |
| Function | Antitoxin component of a type II toxin-antitoxin (TA) system (Pubmed:24923448). A labile antitoxin that counteracts the effect of cognate toxin YafQ (Pubmed:24923448). The YafQ-DinJ heterotetramer binds the consensus sequence 5'-TTTGAGCTACA-3' in the dinJ promoter; DinJ also binds DNA but not as well as the YafQ-DinJ complex (Pubmed:24923448). Binding to the dinJ represses expression of the promoter (By similarity). {ECO:0000250|UniProtKB:Q47150, ECO:0000269|Pubmed:24923448}. |
| Pubmed ID | 24923448 |
| Domain | CDD:412776 |
| Functional Category | Antitoxin_type_2_and_DNA-binding |
| Uniprot ID | A0A140ND86 |
| ORF Length (Amino Acid) | 86 |
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| Conservation Analysis |
No. of Species: 23
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 246242 | 246502 | - | NC_000913.3 | Escherichia coli str. K-12 substr. MG1655 |
| 2 | 284208 | 284468 | - | NC_002695.2 | Escherichia coli O157:H7 str. Sakai |
| 3 | 3363706 | 3363966 | + | NZ_CP061527.1 | Shigella dysenteriae |
| 4 | 3679982 | 3680242 | - | NC_003197.2 | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |
| 5 | 2202904 | 2203164 | + | NZ_CP011104.1 | Photorhabdus thracensis |
| 6 | 3209571 | 3209849 | + | NZ_CP060401.1 | Xenorhabdus nematophila |
| 7 | 284122 | 284382 | - | NZ_CP014527.1 | Haematospirillum jordaniae |
| 8 | 5320 | 5580 | - | NZ_CP014527.1 | Haematospirillum jordaniae |
| 9 | 5546532 | 5546792 | - | NC_008786.1 | Verminephrobacter eiseniae EF01-2 |
| 10 | 3212130 | 3212393 | - | NC_008786.1 | Verminephrobacter eiseniae EF01-2 |
| 11 | 1455496 | 1455756 | - | NZ_CP053627.1 | Xylella taiwanensis |
| 12 | 3752979 | 3753236 | - | NZ_CP023525.1 | Cedecea neteri |
| 13 | 65814 | 66074 | + | NZ_CP010401.1 | Bartonella ancashensis |
| 14 | 16477 | 16758 | + | NZ_AP017660.1 | Sphingobium cloacae |
| 15 | 2537382 | 2537663 | + | NZ_CP018221.1 | Tardibacter chloracetimidivorans |
| 16 | 3407078 | 3407359 | - | NC_014006.1 | Sphingobium japonicum UT26S |
| 17 | 22437 | 22718 | - | NZ_CP020541.1 | Sphingobium herbicidovorans |
| 18 | 571117 | 571389 | - | NZ_CP058235.1 | Bartonella alsatica |
| 19 | 227470 | 227733 | - | NC_015178.1 | Acidiphilium multivorum AIU301 |
| 20 | 952658 | 952921 | - | NZ_CP053923.1 | Defluviicoccus vanus |
| 21 | 1258110 | 1258373 | + | NZ_AP019864.1 | Rickettsia heilongjiangensis |
| 22 | 1247400 | 1247663 | + | NC_010263.3 | Rickettsia rickettsii str. Iowa |
| 23 | 1247038 | 1247301 | + | NC_003103.1 | Rickettsia conorii str. Malish 7 |
| 24 | 1254016 | 1254279 | + | NC_016639.1 | Rickettsia slovaca 13-B |
| 25 | 464140 | 464403 | + | NZ_AP019563.1 | Rickettsia asiatica |
| 26 | 465171 | 465434 | - | NZ_LN794217.1 | Rickettsia monacensis |
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