Result : O32583
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Sulfur carrier protein ThiS (Thiamine biosynthesis protein ThiS) |
| NCBI Accession ID | M88701.1 |
| Organism | Escherichia coli (strain K12) |
| Left | 3520 |
| Right | 3720 |
| Strand | + |
| Nucleotide Sequence | ATGCAGATCCTGTTTAACGATCAAGCGATGCAGTGCGCCGCCGGGCAAACTGTTCACGAACTACTGGAGCAACTCGACCAACGACAAGCGGGCGCGGCCCTGGCGATTAATCAGCAAATCGTCCCGCGTGAGCAGTGGGCGCAACATATCGTGCAGGATGGCGACCAGATCCTGCTTTTTCAGGTTATTGCAGGGGGTTGA |
| Sequence | MQILFNDQAMQCAAGQTVHELLEQLDQRQAGAALAINQQIVPREQWAQHIVQDGDQILLFQVIAGG |
| Source of smORF | Swiss-Prot |
| Function | Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate. {ECO:0000269|Pubmed:9632726}. |
| Pubmed ID | 8432721 8265357 9278503 16738553 9632726 10082377 11438688 11135670 16388576 |
| Domain | CDD:421700 |
| Functional Category | Others |
| Uniprot ID | O32583 |
| ORF Length (Amino Acid) | 66 |
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| Conservation Analysis |
No. of Species: 121
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 4192637 | 4192837 | - | NC_000913.3 | Escherichia coli str. K-12 substr. MG1655 |
| 2 | 4211470 | 4211670 | - | NC_004337.2 | Shigella flexneri 2a str. 301 |
| 3 | 125907 | 126107 | - | NZ_CP061527.1 | Shigella dysenteriae |
| 4 | 5001589 | 5001789 | - | NC_002695.2 | Escherichia coli O157:H7 str. Sakai |
| 5 | 3134750 | 3134950 | - | NZ_CP057657.1 | Escherichia fergusonii |
| 6 | 4164090 | 4164290 | - | NZ_AP014857.1 | Escherichia albertii |
| 7 | 231607 | 231807 | - | NZ_LR134340.1 | Escherichia marmotae |
| 8 | 4378937 | 4379137 | - | NC_003197.2 | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |
| 9 | 831216 | 831416 | - | NZ_CP045205.1 | Citrobacter telavivensis |
| 10 | 839894 | 840094 | + | NZ_LT556085.1 | Citrobacter amalonaticus |
| 11 | 2959263 | 2959463 | - | NZ_CP033744.1 | Citrobacter freundii |
| 12 | 2111472 | 2111672 | + | NZ_CP044098.1 | Citrobacter portucalensis |
| 13 | 3142809 | 3143009 | + | NZ_CP038469.1 | Citrobacter tructae |
| 14 | 5594109 | 5594309 | - | NZ_CP015113.1 | Kosakonia radicincitans |
| 15 | 246398 | 246598 | - | NZ_CP063425.1 | Kosakonia pseudosacchari |
| 16 | 3401777 | 3401977 | - | NZ_CP016337.1 | Kosakonia sacchari |
| 17 | 2774771 | 2774971 | + | NC_009792.1 | Citrobacter koseri ATCC BAA-895 |
| 18 | 5131354 | 5131554 | + | NZ_CP014007.2 | Kosakonia oryzae |
| 19 | 3951056 | 3951256 | + | NC_013716.1 | Citrobacter rodentium ICC168 |
| 20 | 2891889 | 2892089 | + | NZ_CP045300.1 | Kosakonia arachidis |
| 21 | 4409277 | 4409477 | + | NZ_CP045845.1 | Kluyvera intermedia |
| 22 | 5875673 | 5875873 | + | NZ_CP060111.1 | Klebsiella michiganensis |
| 23 | 4290784 | 4290984 | + | NZ_CP011602.1 | Phytobacter ursingii |
| 24 | 3306614 | 3306814 | + | NZ_CP045769.1 | Enterobacter cancerogenus |
| 25 | 5008291 | 5008491 | + | NZ_CP041247.1 | Raoultella electrica |
| 26 | 5305752 | 5305952 | + | NZ_CP046672.1 | Raoultella ornithinolytica |
| 27 | 2004701 | 2004901 | - | NZ_CP026047.1 | Raoultella planticola |
| 28 | 168124 | 168324 | + | NZ_CP051548.1 | Phytobacter diazotrophicus |
| 29 | 3846025 | 3846225 | + | NC_017910.1 | Shimwellia blattae DSM 4481 = NBRC 105725 |
| 30 | 5328296 | 5328496 | + | NZ_CP050508.1 | Raoultella terrigena |
| 31 | 3730266 | 3730466 | - | NZ_CP023529.1 | Lelliottia amnigena |
| 32 | 4791899 | 4792099 | + | NZ_CP023525.1 | Cedecea neteri |
| 33 | 4366669 | 4366869 | + | NZ_LR134201.1 | Cedecea lapagei |
| 34 | 259238 | 259438 | - | NZ_CP009756.1 | Enterobacter cloacae |
| 35 | 2371157 | 2371357 | + | NZ_CP025034.2 | Enterobacter sp. SGAir0187 |
| 36 | 3458171 | 3458371 | - | NZ_CP017279.1 | Enterobacter ludwigii |
| 37 | 5818197 | 5818397 | + | NZ_CP036175.1 | Klebsiella huaxiensis |
| 38 | 4929617 | 4929817 | + | NZ_LR134475.1 | Klebsiella aerogenes |
| 39 | 246064 | 246264 | - | NZ_CP043318.1 | Enterobacter chengduensis |
| 40 | 4574075 | 4574275 | + | NZ_CP013990.1 | Leclercia adecarboxylata |
| 41 | 245017 | 245217 | - | NC_015968.1 | Enterobacter soli |
| 42 | 231172 | 231372 | - | NZ_CP017184.1 | Enterobacter roggenkampii |
| 43 | 2729411 | 2729611 | - | NZ_AP019007.1 | Enterobacter oligotrophicus |
| 44 | 233236 | 233436 | - | NZ_CP027986.1 | Enterobacter sichuanensis |
| 45 | 216993 | 217193 | - | NZ_AP022508.1 | Enterobacter bugandensis |
| 46 | 242015 | 242215 | - | NC_016845.1 | Klebsiella pneumoniae subsp. pneumoniae HS11286 |
| 47 | 5259722 | 5259922 | + | NZ_CP054254.1 | Klebsiella variicola |
| 48 | 295680 | 295880 | - | NZ_LR134494.1 | Serratia quinivorans |
| 49 | 4970205 | 4970405 | + | NZ_CP065838.1 | Klebsiella quasipneumoniae |
| 50 | 4309043 | 4309243 | + | NZ_CP054058.1 | Scandinavium goeteborgense |
| 51 | 269438 | 269638 | - | NZ_CP042220.2 | Dickeya poaceiphila |
| 52 | 295424 | 295624 | - | NZ_LT906479.1 | Serratia ficaria |
| 53 | 2145367 | 2145567 | - | NZ_CP053416.1 | Salmonella bongori |
| 54 | 1417422 | 1417622 | + | NZ_CP015750.1 | Pectobacterium wasabiae CFBP 3304 |
| 55 | 285582 | 285782 | - | NZ_CP048784.1 | Serratia liquefaciens |
| 56 | 4249117 | 4249317 | + | NZ_AP023184.1 | Buttiauxella agrestis |
| 57 | 523373 | 523573 | - | NC_005126.1 | Photorhabdus laumondii subsp. laumondii TTO1 |
| 58 | 3680148 | 3680348 | + | NZ_CP034035.1 | Brenneria rubrifaciens |
| 59 | 4750081 | 4750281 | - | NZ_CP016948.1 | Serratia surfactantfaciens |
| 60 | 3923485 | 3923685 | + | NZ_CP014137.1 | Brenneria goodwinii |
| 61 | 1931886 | 1932086 | + | NZ_CP011078.1 | Yersinia ruckeri |
| 62 | 260506 | 260706 | - | NZ_CP034938.1 | Pectobacterium odoriferum |
| 63 | 1833001 | 1833201 | - | NZ_CP065640.1 | Serratia rubidaea |
| 64 | 282906 | 283106 | - | NC_015567.1 | Serratia plymuthica AS9 |
| 65 | 273078 | 273278 | - | NZ_CP009125.1 | Pectobacterium atrosepticum |
| 66 | 4570867 | 4571067 | + | NZ_CP051652.1 | Pectobacterium carotovorum |
| 67 | 4410461 | 4410661 | + | NZ_CP035129.1 | Kosakonia cowanii |
| 68 | 362161 | 362361 | - | NZ_CP012266.1 | Cronobacter dublinensis subsp. dublinensis LMG 23823 |
| 69 | 2217907 | 2218107 | + | NZ_CP014136.1 | Gibbsiella quercinecans |
| 70 | 3675597 | 3675797 | + | NZ_CP012268.1 | Cronobacter muytjensii ATCC 51329 |
| 71 | 426948 | 427148 | - | NC_012962.1 | Photorhabdus asymbiotica |
| 72 | 3827002 | 3827202 | + | NZ_FO704550.1 | Xenorhabdus doucetiae |
| 73 | 3798404 | 3798604 | + | NZ_CP013940.1 | Cronobacter malonaticus LMG 23826 |
| 74 | 3078312 | 3078512 | + | NZ_CP027107.1 | Cronobacter sakazakii |
| 75 | 2939988 | 2940188 | + | NZ_CP060401.1 | Xenorhabdus nematophila |
| 76 | 4768528 | 4768728 | + | NZ_CP071320.1 | Serratia ureilytica |
| 77 | 269485 | 269685 | - | NZ_CP031560.1 | Dickeya dianthicola |
| 78 | 1525654 | 1525854 | - | NZ_CP040428.1 | Jejubacter calystegiae |
| 79 | 310819 | 311019 | - | NZ_LT615367.1 | Dickeya aquatica |
| 80 | 637983 | 638183 | + | NZ_CP023536.1 | Providencia alcalifaciens |
| 81 | 3811480 | 3811680 | + | NZ_CP015749.1 | Pectobacterium parmentieri |
| 82 | 3065178 | 3065378 | + | NZ_FO704551.1 | Xenorhabdus poinarii G6 |
| 83 | 4309172 | 4309372 | + | NC_012880.1 | Musicola paradisiaca Ech703 |
| 84 | 368301 | 368501 | - | NZ_CP012264.1 | Cronobacter condimenti 1330 |
| 85 | 4036057 | 4036257 | - | NZ_CP017482.1 | Pectobacterium polaris |
| 86 | 4377799 | 4377999 | + | NC_012912.1 | Dickeya chrysanthemi Ech1591 |
| 87 | 264528 | 264728 | - | NZ_CP038662.1 | Serratia nematodiphila |
| 88 | 3878312 | 3878512 | + | NC_013892.1 | Xenorhabdus bovienii SS-2004 |
| 89 | 581478 | 581678 | + | NZ_CP007044.2 | Chania multitudinisentens RB-25 |
| 90 | 235473 | 235673 | - | NZ_CP012871.1 | [Enterobacter] lignolyticus |
| 91 | 2503783 | 2503983 | + | NZ_CP009460.1 | Dickeya fangzhongdai |
| 92 | 3685320 | 3685520 | - | NZ_CP016176.1 | Xenorhabdus hominickii |
| 93 | 353158 | 353358 | - | NZ_CP012257.1 | Cronobacter universalis NCTC 9529 |
| 94 | 1423865 | 1424065 | + | NZ_CP042941.1 | Atlantibacter hermannii |
| 95 | 266054 | 266254 | - | NC_014500.1 | Dickeya dadantii 3937 |
| 96 | 2435730 | 2435930 | - | NZ_CP015137.1 | Dickeya solani IPO 2222 |
| 97 | 1876310 | 1876510 | - | NZ_CP047495.1 | Pectobacterium brasiliense |
| 98 | 419050 | 419250 | + | NZ_CP029736.1 | Providencia rettgeri |
| 99 | 2814663 | 2814863 | + | NZ_CP006664.1 | Edwardsiella anguillarum ET080813 |
| 100 | 282239 | 282439 | - | NZ_CP038498.1 | Pectobacterium punjabense |
| 101 | 2240455 | 2240655 | - | NZ_CP011254.1 | Serratia fonticola |
| 102 | 4663809 | 4664009 | + | NZ_CP065044.1 | Pectobacterium aroidearum |
| 103 | 276792 | 276992 | - | NZ_CP025799.1 | Dickeya zeae |
| 104 | 4247955 | 4248155 | - | NZ_CP031123.2 | Providencia huaxiensis |
| 105 | 1197018 | 1197218 | + | NZ_CP026364.1 | Proteus hauseri |
| 106 | 453632 | 453832 | - | NZ_LS483422.1 | Providencia heimbachae |
| 107 | 496797 | 496997 | + | NZ_CP020388.1 | Pluralibacter gergoviae |
| 108 | 4011451 | 4011651 | + | NZ_CP034752.1 | Jinshanibacter zhutongyuii |
| 109 | 3582072 | 3582272 | + | NZ_CP047349.1 | Proteus terrae subsp. cibarius |
| 110 | 3221129 | 3221329 | - | NZ_CP009787.1 | Yersinia rohdei |
| 111 | 404889 | 405089 | - | NZ_CP048796.1 | Providencia vermicola |
| 112 | 393556 | 393768 | - | NZ_CP072455.1 | Xenorhabdus budapestensis |
| 113 | 842637 | 842837 | + | NZ_CP054043.1 | Yersinia mollaretii ATCC 43969 |
| 114 | 4505104 | 4505304 | + | NZ_CP006569.1 | Sodalis praecaptivus |
| 115 | 3602089 | 3602289 | + | NZ_CP065534.1 | Lonsdalea populi |
| 116 | 4228719 | 4228886 | + | NZ_LR134373.1 | Yersinia pseudotuberculosis |
| 117 | 1972208 | 1972375 | - | NZ_CP007230.1 | Yersinia similis |
| 118 | 1440919 | 1441119 | + | NZ_CP011104.1 | Photorhabdus thracensis |
| 119 | 3511172 | 3511372 | + | NZ_LR134531.1 | Pragia fontium |
| 120 | 4346627 | 4346791 | + | NZ_CP046293.1 | Yersinia intermedia |
| 121 | 3287699 | 3287899 | + | NZ_CP067057.1 | Rahnella aceris |
| 122 | 1340551 | 1340751 | - | NZ_CP023009.1 | Lonsdalea britannica |
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| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NC_000913.3
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF06968.15 | 1.0 | 121 | 769.0 | same-strand | Biotin and Thiamin Synthesis associated domain |
| 2 | PF04055.23 | 1.0 | 121 | 769.0 | same-strand | Radical SAM superfamily |
| 3 | PF05690.16 | 1.0 | 121 | 2.0 | same-strand | Thiazole biosynthesis protein ThiG |
| 4 | PF00899.23 | 1.0 | 121 | -15.5 | same-strand | ThiF family |
| 5 | PF02581.19 | 1.0 | 121 | 732.0 | same-strand | Thiamine monophosphate synthase |
| 6 | PF01964.20 | 0.99 | 120 | 1367 | same-strand | Radical SAM ThiC family |
| 7 | PF13667.8 | 0.99 | 120 | 1367 | same-strand | ThiC-associated domain |
| 8 | PF04353.15 | 0.81 | 98 | 3558 | same-strand | Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ |
| 9 | PF00293.30 | 0.89 | 108 | 4152.0 | opposite-strand | NUDIX domain |
| 10 | PF09297.13 | 0.9 | 109 | 4154.0 | opposite-strand | NADH pyrophosphatase zinc ribbon domain |
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