Result : O32221
| Protein Information |
| Information Type | Description |
|---|---|
| Protein name | Copper chaperone CopZ (Copper-ion-binding protein) |
| NCBI Accession ID | AL009126.3 |
| Organism | Bacillus subtilis (strain 168) |
| Left | 3443613 |
| Right | 3443822 |
| Strand | - |
| Nucleotide Sequence | ATGGAACAAAAAACATTGCAAGTTGAAGGAATGTCTTGTCAGCACTGCGTCAAAGCAGTAGAAACAAGCGTAGGAGAACTGGACGGCGTCAGTGCCGTTCATGTCAATCTGGAAGCGGGTAAAGTCGATGTTTCGTTTGATGCTGACAAAGTATCAGTCAAAGATATTGCGGATGCGATAGAAGATCAGGGCTATGACGTAGCCAAGTGA |
| Sequence | MEQKTLQVEGMSCQHCVKAVETSVGELDGVSAVHVNLEAGKVDVSFDADKVSVKDIADAIEDQGYDVAK |
| Source of smORF | Swiss-Prot |
| Function | Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-transporting ATPase CopA. Functions in E.coli to transfer Cu(+) to CopA missing its first metal-binding domain (Pubmed:25899340). {ECO:0000269|Pubmed:25899340}. |
| Pubmed ID | 9384377 12644235 14663075 25899340 12238948 12600214 14621987 |
| Domain | CDD:412222 |
| Functional Category | Metal-binding |
| Uniprot ID | O32221 |
| ORF Length (Amino Acid) | 69 |
++ More..
| Conservation Analysis |
No. of Species: 163
| Sr.No. | Left Position | Right Position | Strand | NCBI Accession id | Species Name |
|---|---|---|---|---|---|
| 1 | 3443613 | 3443822 | - | NC_000964.3 | Bacillus subtilis subsp. subtilis str. 168 |
| 2 | 3256528 | 3256737 | - | NZ_CP048852.1 | Bacillus tequilensis |
| 3 | 3312193 | 3312402 | - | NZ_CP013984.1 | Bacillus inaquosorum |
| 4 | 3251938 | 3252147 | - | NZ_CP034943.1 | Bacillus subtilis subsp. spizizenii ATCC 6633 = JCM 2499 |
| 5 | 2810990 | 2811199 | + | NZ_CP029364.1 | Bacillus halotolerans |
| 6 | 3303585 | 3303794 | - | NZ_CP033052.1 | Bacillus vallismortis |
| 7 | 3229348 | 3229557 | - | NZ_CP051464.1 | Bacillus mojavensis |
| 8 | 3278959 | 3279165 | - | NZ_CP053376.1 | Bacillus amyloliquefaciens |
| 9 | 738566 | 738772 | + | NZ_CP011937.1 | Bacillus velezensis |
| 10 | 3401243 | 3401452 | - | NC_006270.3 | Bacillus licheniformis DSM 13 = ATCC 14580 |
| 11 | 3629563 | 3629772 | - | NZ_CP023665.1 | Bacillus paralicheniformis |
| 12 | 3813594 | 3813803 | - | NZ_LT603683.1 | Bacillus glycinifermentans |
| 13 | 1556213 | 1556419 | + | NZ_CP019699.1 | Novibacillus thermophilus |
| 14 | 1850045 | 1850251 | + | NZ_CP024035.1 | Priestia aryabhattai |
| 15 | 2261360 | 2261566 | + | NZ_CP043404.1 | Bacillus safensis |
| 16 | 3010807 | 3011013 | - | NZ_CP048104.1 | Kroppenstedtia pulmonis |
| 17 | 2801385 | 2801591 | - | NC_022524.1 | Bacillus infantis NRRL B-14911 |
| 18 | 333231 | 333437 | - | NZ_LR134089.1 | Staphylococcus saprophyticus |
| 19 | 699990 | 700196 | + | NZ_CP009416.1 | Jeotgalibacillus malaysiensis |
| 20 | 1262025 | 1262231 | + | NZ_CP041666.1 | Radiobacillus deserti |
| 21 | 4093361 | 4093567 | - | NZ_CP053989.1 | Niallia circulans |
| 22 | 3047480 | 3047686 | - | NZ_CP011150.1 | Bacillus altitudinis |
| 23 | 633916 | 634092 | + | NZ_CP031223.1 | Psychrobacillus glaciei |
| 24 | 514000 | 514188 | - | NZ_CP016538.2 | Planococcus maritimus |
| 25 | 516080 | 516268 | - | NZ_CP059540.1 | Planococcus maritimus |
| 26 | 2361914 | 2362120 | + | NZ_CP017786.1 | Bacillus xiamenensis |
| 27 | 4795591 | 4795797 | + | NZ_CP018866.1 | Sutcliffiella cohnii |
| 28 | 208308 | 208496 | - | NZ_CP013659.2 | Planococcus rifietoensis |
| 29 | 1100150 | 1100356 | - | NZ_CP031092.1 | Salicibibacter kimchii |
| 30 | 3516226 | 3516405 | + | NZ_CP031092.1 | Salicibibacter kimchii |
| 31 | 2551953 | 2552159 | + | NZ_CP031092.1 | Salicibibacter kimchii |
| 32 | 535104 | 535292 | - | NZ_CP016539.2 | Planococcus plakortidis |
| 33 | 3052833 | 3053009 | - | NZ_CP016539.2 | Planococcus plakortidis |
| 34 | 3071334 | 3071540 | - | NZ_CP016539.2 | Planococcus plakortidis |
| 35 | 1621749 | 1621955 | + | NZ_CP040336.1 | Bacillus luti |
| 36 | 3741681 | 3741887 | - | NC_011725.1 | Bacillus cereus B4264 |
| 37 | 2687383 | 2687589 | + | NZ_CP035485.1 | Salicibibacter halophilus |
| 38 | 356070 | 356276 | + | NZ_CP035485.1 | Salicibibacter halophilus |
| 39 | 1089665 | 1089871 | - | NZ_CP035485.1 | Salicibibacter halophilus |
| 40 | 3533507 | 3533713 | - | NC_007530.2 | Bacillus anthracis str. 'Ames Ancestor' |
| 41 | 1122839 | 1123045 | + | NZ_CP065425.1 | Heyndrickxia vini |
| 42 | 1406767 | 1406976 | + | NZ_CP022096.2 | Staphylococcus pettenkoferi |
| 43 | 1156213 | 1156419 | - | NZ_CP009709.1 | Weizmannia coagulans DSM 1 = ATCC 7050 |
| 44 | 211876 | 212082 | + | NZ_LS483476.1 | Lederbergia lentus |
| 45 | 4794880 | 4795086 | + | NZ_CP030926.1 | Peribacillus butanolivorans |
| 46 | 232862 | 233041 | + | NZ_CP038015.1 | Paenisporosarcina antarctica |
| 47 | 502522 | 502710 | - | NZ_CP016537.2 | Planococcus halocryophilus |
| 48 | 87112 | 87291 | - | NZ_CP017560.1 | Sporosarcina ureilytica |
| 49 | 2501743 | 2501952 | - | NZ_CP017962.1 | Virgibacillus halodenitrificans |
| 50 | 2465267 | 2465446 | - | NZ_CP017962.1 | Virgibacillus halodenitrificans |
| 51 | 590491 | 590667 | + | NC_002570.2 | Alkalihalobacillus halodurans C-125 |
| 52 | 3558751 | 3558957 | - | NZ_CP064875.1 | Bacillus toyonensis |
| 53 | 2489165 | 2489371 | + | NZ_CP041305.1 | Cytobacillus ciccensis |
| 54 | 485795 | 485983 | - | NZ_CP016540.2 | Planococcus versutus |
| 55 | 503158 | 503346 | - | NZ_CP016543.2 | Planococcus donghaensis |
| 56 | 387071 | 387277 | - | NZ_CP008724.1 | Staphylococcus xylosus |
| 57 | 3388430 | 3388636 | - | NZ_CP016020.1 | Bacillus weihaiensis |
| 58 | 577762 | 577968 | + | NZ_CP016020.1 | Bacillus weihaiensis |
| 59 | 573095 | 573301 | + | NZ_CP068053.1 | Peribacillus psychrosaccharolyticus |
| 60 | 2293092 | 2293301 | - | NZ_AP021853.1 | Sporolactobacillus terrae |
| 61 | 3738787 | 3738993 | - | NZ_CP032365.1 | Bacillus wiedmannii |
| 62 | 331771 | 331977 | - | NZ_CP017704.1 | Peribacillus simplex NBRC 15720 = DSM 1321 |
| 63 | 96599 | 96775 | - | NZ_CP022437.1 | Virgibacillus necropolis |
| 64 | 1568267 | 1568446 | + | NZ_CP022437.1 | Virgibacillus necropolis |
| 65 | 3308335 | 3308541 | - | NZ_CP023704.1 | Caldibacillus thermoamylovorans |
| 66 | 2608736 | 2608942 | + | NZ_LR134304.1 | Staphylococcus schweitzeri |
| 67 | 1253393 | 1253581 | + | NZ_CP013661.2 | Planococcus kocurii |
| 68 | 44975 | 45181 | - | NC_013792.1 | Alkalihalobacillus pseudofirmus OF4 |
| 69 | 2061685 | 2061897 | + | NZ_CP065712.1 | Staphylococcus auricularis |
| 70 | 2333366 | 2333572 | - | NZ_CP018199.1 | Staphylococcus succinus |
| 71 | 511687 | 511875 | - | NZ_CP019401.1 | Planococcus faecalis |
| 72 | 2647869 | 2648075 | + | NC_007795.1 | Staphylococcus aureus subsp. aureus NCTC 8325 |
| 73 | 538217 | 538405 | - | NZ_CP016534.2 | Planococcus antarcticus DSM 14505 |
| 74 | 86512 | 86718 | + | NZ_CP029797.1 | Paraliobacillus zengyii |
| 75 | 1483704 | 1483910 | - | NZ_CP017705.1 | Brevibacillus laterosporus DSM 25 |
| 76 | 1497868 | 1498047 | + | NZ_CP024848.1 | Oceanobacillus zhaokaii |
| 77 | 206288 | 206494 | - | NZ_CP034248.1 | Paenibacillus lentus |
| 78 | 492353 | 492559 | - | NZ_CP064056.1 | Staphylococcus lloydii |
| 79 | 369566 | 369772 | - | NZ_LR134242.1 | Staphylococcus warneri |
| 80 | 4190822 | 4191028 | - | NZ_CP042593.1 | Bacillus dafuensis |
| 81 | 2472620 | 2472826 | + | NZ_LT906460.1 | Staphylococcus simiae |
| 82 | 1749990 | 1750196 | + | NZ_CP007601.1 | Staphylococcus capitis subsp. capitis |
| 83 | 1462724 | 1462900 | - | NZ_CP038012.1 | Sporosarcina pasteurii |
| 84 | 2619877 | 2620056 | - | NZ_CP038012.1 | Sporosarcina pasteurii |
| 85 | 2533235 | 2533441 | - | NC_016627.1 | Acetivibrio clariflavus DSM 19732 |
| 86 | 1880142 | 1880348 | - | NZ_CP014022.1 | Staphylococcus lugdunensis |
| 87 | 1966530 | 1966739 | - | NC_013791.2 | Alkalihalobacillus pseudofirmus OF4 |
| 88 | 1110220 | 1110426 | + | NC_022737.1 | Staphylococcus pasteuri SP1 |
| 89 | 404729 | 404941 | + | NZ_LT906462.1 | Mammaliicoccus stepanovicii |
| 90 | 272364 | 272570 | + | NZ_CP010820.1 | Lysinibacillus fusiformis |
| 91 | 4815612 | 4815818 | - | NZ_CP010820.1 | Lysinibacillus fusiformis |
| 92 | 795793 | 795999 | + | NZ_CP015378.1 | Fictibacillus phosphorivorans |
| 93 | 3927415 | 3927624 | + | NZ_CP022983.1 | Cytobacillus kochii |
| 94 | 2765802 | 2765978 | + | NZ_CP017703.1 | Aeribacillus pallidus |
| 95 | 2196502 | 2196678 | + | NZ_CP017703.1 | Aeribacillus pallidus |
| 96 | 2918387 | 2918563 | + | NZ_CP017703.1 | Aeribacillus pallidus |
| 97 | 38690 | 38896 | + | NZ_CP006837.1 | Lysinibacillus varians |
| 98 | 40296 | 40502 | - | NZ_CP019980.1 | Lysinibacillus sphaericus |
| 99 | 4183 | 4389 | - | NZ_CP019980.1 | Lysinibacillus sphaericus |
| 100 | 2366689 | 2366898 | - | NZ_CP011366.1 | Salinicoccus halodurans |
| 101 | 688339 | 688545 | - | NZ_CP022315.1 | Virgibacillus phasianinus |
| 102 | 2474743 | 2474922 | + | NZ_CP022315.1 | Virgibacillus phasianinus |
| 103 | 2493703 | 2493882 | + | NZ_CP022315.1 | Virgibacillus phasianinus |
| 104 | 725912 | 726091 | - | NZ_CP022315.1 | Virgibacillus phasianinus |
| 105 | 2460896 | 2461072 | - | NZ_CP011361.2 | Salimicrobium jeotgali |
| 106 | 1604399 | 1604575 | - | NZ_CP012152.1 | Anoxybacillus gonensis |
| 107 | 2356766 | 2356942 | + | NZ_CP061336.1 | Ruminiclostridium herbifermentans |
| 108 | 1636399 | 1636575 | + | NZ_CP015438.1 | Anoxybacillus amylolyticus |
| 109 | 2060469 | 2060645 | + | NZ_CP070511.1 | Parageobacillus toebii |
| 110 | 2166391 | 2166567 | + | NZ_CP070511.1 | Parageobacillus toebii |
| 111 | 3112516 | 3112722 | - | NZ_CP021850.1 | Pseudoclostridium thermosuccinogenes |
| 112 | 1651620 | 1651820 | + | NZ_CP026520.1 | Paenibacillus chitinolyticus |
| 113 | 1645940 | 1646146 | - | NZ_CP064060.1 | Anoxybacillus caldiproteolyticus |
| 114 | 925520 | 925696 | + | NC_006510.1 | Geobacillus kaustophilus HTA426 |
| 115 | 53200 | 53376 | + | NZ_CP061470.1 | Geobacillus zalihae |
| 116 | 3057037 | 3057213 | - | NZ_CP018058.1 | Geobacillus thermocatenulatus |
| 117 | 398292 | 398468 | + | NZ_CP061472.1 | Geobacillus thermoleovorans |
| 118 | 726748 | 726927 | + | NC_014377.1 | Thermosediminibacter oceani DSM 16646 |
| 119 | 2348405 | 2348611 | + | NZ_CP013114.1 | Staphylococcus equorum |
| 120 | 1194631 | 1194813 | + | NC_004193.1 | Oceanobacillus iheyensis HTE831 |
| 121 | 2464569 | 2464745 | - | NZ_CP014342.1 | Geobacillus subterraneus |
| 122 | 2428926 | 2429102 | - | NZ_CP014342.1 | Geobacillus subterraneus |
| 123 | 587722 | 587898 | + | NZ_CP024109.1 | Bacillus cytotoxicus |
| 124 | 465871 | 466077 | - | NZ_AP018587.1 | Staphylococcus caprae |
| 125 | 1069387 | 1069599 | + | NZ_CP013023.1 | Paenibacillus bovis |
| 126 | 2150375 | 2150581 | - | NZ_CP048649.1 | Aminipila butyrica |
| 127 | 2774828 | 2775004 | - | NZ_CP016622.1 | Parageobacillus thermoglucosidasius |
| 128 | 1935523 | 1935726 | + | NZ_CP022657.1 | Tumebacillus algifaecis |
| 129 | 1544409 | 1544585 | + | NZ_CP012024.1 | Bacillus smithii |
| 130 | 3329250 | 3329429 | + | NZ_CP008876.1 | Terribacillus goriensis |
| 131 | 2301759 | 2301932 | + | NZ_CP014616.1 | Sporosarcina psychrophila |
| 132 | 2062931 | 2063128 | - | NC_011898.1 | Ruminiclostridium cellulolyticum H10 |
| 133 | 435751 | 435951 | + | NZ_CP009428.1 | Paenibacillus odorifer |
| 134 | 1517439 | 1517618 | + | NZ_CP020772.1 | Halobacillus mangrovi |
| 135 | 1476044 | 1476214 | + | NZ_CP020772.1 | Halobacillus mangrovi |
| 136 | 619505 | 619705 | + | NZ_CP019659.1 | Paenibacillus larvae subsp. larvae |
| 137 | 1745305 | 1745481 | + | NZ_CP016502.1 | Acetivibrio thermocellus DSM 2360 |
| 138 | 2786845 | 2787054 | - | NC_014376.1 | [Clostridium] saccharolyticum WM1 |
| 139 | 3524546 | 3524746 | + | NZ_CP016809.1 | Paenibacillus ihbetae |
| 140 | 2646564 | 2646767 | - | NZ_CP016809.1 | Paenibacillus ihbetae |
| 141 | 2769180 | 2769380 | + | NZ_CP045298.1 | Paenibacillus brasilensis |
| 142 | 5143802 | 5144002 | - | NZ_CP020028.1 | Paenibacillus kribbensis |
| 143 | 2116642 | 2116842 | + | NC_016641.1 | Paenibacillus terrae HPL-003 |
| 144 | 3398536 | 3398712 | - | NC_017668.1 | Halobacillus halophilus DSM 2266 |
| 145 | 2901179 | 2901358 | - | NC_017668.1 | Halobacillus halophilus DSM 2266 |
| 146 | 4631981 | 4632187 | + | NZ_CP014167.1 | Paenibacillus yonginensis |
| 147 | 2024161 | 2024367 | - | NZ_CP040676.1 | Exiguobacterium mexicanum |
| 148 | 546392 | 546592 | + | NZ_CP013652.1 | Paenibacillus naphthalenovorans |
| 149 | 458902 | 459105 | + | NZ_CP009286.1 | Paenibacillus stellifer |
| 150 | 3796309 | 3796485 | - | NZ_LR134338.1 | Brevibacillus brevis |
| 151 | 3239916 | 3240095 | - | NZ_CP040924.1 | Clostridium thermarum |
| 152 | 1608800 | 1609000 | - | NZ_CP045295.1 | Paenibacillus cellulositrophicus |
| 153 | 3294857 | 3295057 | - | NZ_CP045295.1 | Paenibacillus cellulositrophicus |
| 154 | 2609059 | 2609259 | - | NZ_CP045293.1 | Paenibacillus guangzhouensis |
| 155 | 4794376 | 4794576 | + | NZ_CP033433.1 | Cohnella candidum |
| 156 | 1625705 | 1625905 | - | NZ_CP011058.1 | Paenibacillus beijingensis |
| 157 | 3114634 | 3114834 | + | NZ_CP041217.1 | Saccharibacillus brassicae |
| 158 | 4540303 | 4540506 | - | NZ_CP021434.1 | Tumebacillus avium |
| 159 | 2214618 | 2214797 | - | NZ_CP015108.1 | Sporosarcina ureae |
| 160 | 7482462 | 7482662 | + | NZ_CP021780.1 | Paenibacillus donghaensis |
| 161 | 2409852 | 2410052 | + | NZ_CP048429.1 | Paenibacillus jilunlii |
| 162 | 508417 | 508617 | + | NZ_CP009287.1 | Paenibacillus graminis |
| 163 | 2385564 | 2385764 | + | NZ_CP068595.1 | Paenibacillus sonchi |
| 164 | 565597 | 565797 | + | NZ_LN831776.1 | Paenibacillus riograndensis SBR5 |
| 165 | 3973666 | 3973869 | + | NZ_CP035492.1 | Paenibacillus protaetiae |
| 166 | 2324140 | 2324310 | - | NZ_AP019308.1 | Paenibacillus baekrokdamisoli |
| 167 | 450420 | 450620 | + | NZ_CP034346.1 | Paenibacillus lutimineralis |
| 168 | 1325277 | 1325453 | - | NZ_CP019573.1 | Abyssicoccus albus |
| 169 | 370332 | 370508 | + | NZ_CP054482.1 | Macrococcus bohemicus |
| 170 | 5505551 | 5505739 | + | NZ_AP022588.1 | Mycolicibacterium sediminis |
| 171 | 467372 | 467572 | + | NZ_CP009285.1 | Paenibacillus borealis |
| 172 | 2214238 | 2214441 | + | NZ_CP034118.1 | Staphylospora marina |
| 173 | 80254 | 80460 | + | NZ_CP026312.1 | Salinigranum rubrum |
| 174 | 1968068 | 1968268 | + | NZ_AP017312.1 | Aneurinibacillus soli |
| 175 | 5340092 | 5340265 | + | NZ_CP043474.1 | Mycobacterium grossiae |
| 176 | 348733 | 348936 | + | NZ_CP004078.1 | Paenibacillus sabinae T27 |
| 177 | 4305258 | 4305458 | + | NZ_CP054614.1 | Paenibacillus barcinonensis |
| 178 | 385082 | 385285 | + | NZ_CP009288.1 | Paenibacillus durus |
| 179 | 648823 | 648999 | - | NZ_AP022617.1 | Mycolicibacterium monacense |
| 180 | 2122660 | 2122866 | - | NZ_CP040863.1 | Rodentibacter heylii |
| 181 | 2885965 | 2886171 | - | NC_016111.1 | Streptomyces cattleya NRRL 8057 = DSM 46488 |
| 182 | 3863715 | 3863894 | + | NZ_CP011253.3 | Pandoraea oxalativorans |
| 183 | 1509645 | 1509824 | - | NZ_LT906435.1 | Pandoraea sputorum |
| 184 | 347958 | 348134 | - | NZ_AP022586.1 | Mycolicibacterium litorale |
| 185 | 2826673 | 2826849 | + | NZ_AP022605.1 | Mycobacterium doricum |
| 186 | 4323536 | 4323712 | + | NZ_AP022610.1 | Mycolicibacterium madagascariense |
| 187 | 2353819 | 2354001 | + | NZ_CP026111.1 | Paraburkholderia terrae |
| 188 | 3329552 | 3329734 | + | NZ_CP011568.3 | Pandoraea thiooxydans |
++ More..
| Neighborhood Conservation Analysis |
* Arrows marked in Genome Diagram shows ORFs; Multiple PFAMs can be mapped to a single ORF.
* 'Small ORF' represents the entry/query analyzed.
* Image generated using 'gggenes'(R-Package).
Neighborhood Representative Chosen(Species): NC_000964.3
| Sr.No. | Domain | Co-occurrence Frequency | No. of species in which domain occurs with smORF | Median distance b/w smORF and domain bearing ORFs | Orientation relative to smORF | PFAM Information |
|---|---|---|---|---|---|---|
| 1 | PF00122.22 | 0.91 | 148 | 82 | same-strand | E1-E2 ATPase |
| 2 | PF00702.28 | 0.91 | 148 | 82.5 | same-strand | haloacid dehalogenase-like hydrolase |
| 3 | PF00403.28 | 0.91 | 148 | 82.5 | same-strand | Heavy-metal-associated domain |
| 4 | PF02583.19 | 0.74 | 121 | 84.0 | same-strand | Metal-sensitive transcriptional repressor |
++ More..